RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM)

CUSIP: 76243J105

Q1 2025 13F Holders as of 31 Mar 2025

Type / Class
Equity / Common Stock, $0.001 par value per share
Shares outstanding
69,012,275
Total 13F shares
64,595,384
Share change
-340,676
Total reported value
$3,424,910,613
Put/Call ratio
16%
Price per share
$52.97
Number of holders
226
Value change
-$18,829,096
Number of buys
126
Number of sells
88

Security key

76243J105

Report period

Q1 2025

Institutions

226

Top holders

10

Top shareholders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
BAKER BROS. ADVISORS LP
13D/G 13F
Company
8.9%
5,604,483
$360,984,750 $0 31 Mar 2025
BlackRock, Inc.
13F 13D/G
Company
6.9%
from 13D/G
6,950,715
$389,101,041 31 Dec 2024
GOLDMAN SACHS GROUP INC
13D/G 13F
THE GOLDMAN SACHS GROUP, INC. · Company
3%
1,818,932
$117,157,406 $0 31 Dec 2024
PRIMECAP MANAGEMENT CO/CA/
13F
Company
9.5%
6,571,190
$367,855,216 31 Dec 2024
13F
RA CAPITAL MANAGEMENT, L.P.
13F
Company
8.8%
6,084,412
$340,605,384 31 Dec 2024
13F
PERCEPTIVE ADVISORS LLC
13F
Company
5.3%
3,680,473
$206,032,879 31 Dec 2024
13F
VANGUARD GROUP INC
13F
Company
5%
3,442,600
$192,716,749 31 Dec 2024
13F
NEA Management Company, LLC
13F
Company
4.2%
2,909,956
$162,899,337 31 Dec 2024
13F
Frazier Life Sciences Management, L.P.
13F
Company
2.7%
1,869,808
$104,671,852 31 Dec 2024
13F
STATE STREET CORP
13F
Company
2.7%
1,840,870
$103,051,903 31 Dec 2024
13F
FEDERATED HERMES, INC.
13F
Company
2.2%
1,549,635
$86,748,568 31 Dec 2024
13F
Polar Capital Holdings Plc
13F
Company
2.2%
1,500,000
$83,970,000 31 Dec 2024
13F
DRIEHAUS CAPITAL MANAGEMENT LLC
13F
Company
1.9%
1,290,975
$72,268,780 31 Dec 2024
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.8%
1,255,799
$70,315,740 31 Dec 2024
13F
JANUS HENDERSON GROUP PLC
13F
Company
1.8%
1,219,554
$68,309,431 31 Dec 2024
13F
ALKEON CAPITAL MANAGEMENT LLC
13F
Company
1.7%
1,167,700
$65,367,846 31 Dec 2024
13F
Rock Springs Capital Management LP
13F
Company
1.7%
1,162,718
$65,088,954 31 Dec 2024
13F
Checkpoint Capital L.P.
13F
Company
1.1%
727,982
$40,752,432 31 Dec 2024
13F
MARSHALL WACE, LLP
13F
Company
1%
692,803
$38,783,112 31 Dec 2024
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
0.99%
685,152
$38,355,000 31 Dec 2024
13F
Hood River Capital Management LLC
13F
Company
0.93%
643,691
$36,033,822 31 Dec 2024
13F
LOOMIS SAYLES & CO L P
13F
Company
0.9%
618,485
$34,623,000 31 Dec 2024
13F
MORGAN STANLEY
13F
Company
0.81%
560,087
$31,353,729 31 Dec 2024
13F
NORTHERN TRUST CORP
13F
Company
0.79%
545,314
$30,526,678 31 Dec 2024
13F
Opaleye Management Inc.
13F
Company
0.72%
500,000
$27,990,000 31 Dec 2024
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.64%
440,250
$24,645,195 31 Dec 2024
13F
Cormorant Asset Management, LP
13F
Company
0.58%
400,000
$22,392,000 31 Dec 2024
13F
ORBIMED ADVISORS LLC
13F
Company
0.58%
400,000
$22,392,000 31 Dec 2024
13F
Sofinnova Investments, Inc.
13F
Company
0.58%
397,428
$22,248,019 31 Dec 2024
13F
VOLORIDGE INVESTMENT MANAGEMENT, LLC
13F
Company
0.55%
380,537
$21,302,461 31 Dec 2024
13F
Pictet Asset Management Holding SA
13F
Company
0.54%
375,349
$21,012,037 31 Dec 2024
13F
S.c.a. Candriam
13F
Individual
0.48%
332,392
$18,607,304 31 Dec 2024
13F
Invesco Ltd.
13F
Company
0.44%
302,846
$16,953,320 31 Dec 2024
13F
SILVERARC CAPITAL MANAGEMENT, LLC
13F
Company
0.4%
273,896
$15,332,698 31 Dec 2024
13F
FRANKLIN RESOURCES INC
13F
Company
0.39%
268,205
$15,014,116 31 Dec 2024
13F
JPMORGAN CHASE & CO
13F
Company
0.38%
264,585
$14,811,468 31 Dec 2024
13F
UBS Group AG
13F
Company
0.37%
254,264
$14,233,698 31 Dec 2024
13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC
13F
Company
0.32%
218,544
$12,234,093 31 Dec 2024
13F
STEMPOINT CAPITAL LP
13F
Company
0.3%
208,016
$11,644,736 31 Dec 2024
13F
NORGES BANK
13F
Company
0.3%
205,649
$11,512,231 31 Dec 2024
13F
Samsara BioCapital, LLC
13F
Company
0.25%
172,647
$9,664,779 31 Dec 2024
13F
LORD, ABBETT & CO. LLC
13F
Company
0.23%
160,651
$8,993,000 31 Dec 2024
13F
Integral Health Asset Management, LLC
13F
Company
0.22%
150,000
$8,397,000 31 Dec 2024
13F
Bank of New York Mellon Corp
13F
Company
0.21%
148,246
$8,298,812 31 Dec 2024
13F
Nuveen Asset Management, LLC
13F
Company
0.21%
146,903
$8,223,630 31 Dec 2024
13F
Walleye Capital LLC
13F
Company
0.21%
144,342
$8,080,265 31 Dec 2024
13F
BALYASNY ASSET MANAGEMENT L.P.
13F
Company
0.2%
138,363
$7,745,561 31 Dec 2024
13F
BARCLAYS PLC
13F
Company
0.2%
135,397
$7,579,525 31 Dec 2024
13F
FIRST TRUST ADVISORS LP
13F
Company
0.17%
118,337
$6,624,505 31 Dec 2024
13F
FMR LLC
13F
Company
0.16%
113,109
$6,331,867 31 Dec 2024
13F

Institutional Holders of RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) as of Q1 2025

As of 31 Mar 2025, RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) was held by 226 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 64,595,384 shares. The largest 10 holders included BlackRock, Inc., RA CAPITAL MANAGEMENT, L.P., PRIMECAP MANAGEMENT CO/CA/, BAKER BROS. ADVISORS LP, VANGUARD GROUP INC, NEA Management Company, LLC, PERCEPTIVE ADVISORS LLC, STATE STREET CORP, FMR LLC, and JANUS HENDERSON GROUP PLC. This page lists 227 institutional shareholders reporting positions in this security for the Q1 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q1 2025 vs Q4 2024 Across Filers

Q4 2024 holders
202
Q1 2025 holders
226
Holder diff
24
Investor Q4 2024 Shares Q1 2025 Shares Share Diff Share Chg % Q4 2024 Value $ Q1 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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