RHYTHM PHARMACEUTICALS, INC. - Common Stock (RYTM)

CUSIP: 76243J105

Q2 2025 13F Holders as of 30 Jun 2025

Type / Class
Equity / Common Stock
Shares outstanding
67,341,788
Total 13F shares
66,543,505
Share change
+1,932,077
Total reported value
$4,204,958,379
Put/Call ratio
274%
Price per share
$63.19
Number of holders
225
Value change
+$136,584,141
Number of buys
125
Number of sells
105

Quarterly Holders Quick Answers

What is CUSIP 76243J105?
CUSIP 76243J105 identifies RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock in SEC institutional holdings data.

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Top shareholders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
BlackRock, Inc.
13F 13D/G
Company
6.9%
from 13D/G
6,854,755
$363,096,374 31 Mar 2025
BAKER BROS. ADVISORS LP
13D/G 13F
Company
8.9%
5,604,483
$360,984,750 $0 31 Mar 2025
RA CAPITAL MANAGEMENT, L.P.
13F
Company
9%
6,084,412
$322,291,304 31 Mar 2025
13F
PRIMECAP MANAGEMENT CO/CA/
13F
Company
8.6%
5,787,322
$306,554,446 31 Mar 2025
13F
PERCEPTIVE ADVISORS LLC
13D/G 13F
Company
6.8%
4,423,441
$284,913,835 $0 31 Mar 2025
VANGUARD GROUP INC
13F
Company
5.1%
3,444,926
$182,477,729 31 Mar 2025
13F
NEA Management Company, LLC
13F
Company
4.3%
2,909,956
$154,140,369 31 Mar 2025
13F
GOLDMAN SACHS GROUP INC
13D/G 13F
THE GOLDMAN SACHS GROUP, INC. · Company
3%
1,818,932
$117,157,406 $0 31 Dec 2024
STATE STREET CORP
13F
Company
2.9%
1,970,733
$104,389,727 31 Mar 2025
13F
JANUS HENDERSON GROUP PLC
13F
Company
2.5%
1,655,350
$90,747,654 31 Mar 2025
13F
FMR LLC
13F
Company
2.5%
1,688,375
$89,433,248 31 Mar 2025
13F
FEDERATED HERMES, INC.
13F
Company
2.4%
1,591,871
$84,321,407 31 Mar 2025
13F
DRIEHAUS CAPITAL MANAGEMENT LLC
13F
Company
2.2%
1,458,022
$77,231,425 31 Mar 2025
13F
WESTFIELD CAPITAL MANAGEMENT CO LP
13F
Company
2%
1,341,092
$71,037,643 31 Mar 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.9%
1,287,168
$68,196,935 31 Mar 2025
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
1.8%
1,199,053
$63,515,000 31 Mar 2025
13F
Checkpoint Capital L.P.
13F
Company
1.3%
907,240
$48,056,503 31 Mar 2025
13F
Rock Springs Capital Management LP
13F
Company
1.2%
834,188
$44,186,938 31 Mar 2025
13F
ALKEON CAPITAL MANAGEMENT LLC
13F
Company
1.2%
817,700
$43,313,569 31 Mar 2025
13F
Frazier Life Sciences Management, L.P.
13F
Company
1%
678,760
$35,953,917 31 Mar 2025
13F
Hood River Capital Management LLC
13F
Company
0.98%
659,431
$34,930,060 31 Mar 2025
13F
LOOMIS SAYLES & CO L P
13F
Company
0.9%
605,764
$32,087,000 31 Mar 2025
13F
NORTHERN TRUST CORP
13F
Company
0.8%
536,206
$28,402,833 31 Mar 2025
13F
MARSHALL WACE, LLP
13F
Company
0.79%
535,103
$28,344,405 31 Mar 2025
13F
MORGAN STANLEY
13F
Company
0.75%
504,049
$26,699,494 31 Mar 2025
13F
Polar Capital Holdings Plc
13F
Company
0.74%
500,000
$26,485,000 31 Mar 2025
13F
Opaleye Management Inc.
13F
Company
0.73%
490,000
$25,955,300 31 Mar 2025
13F
Sofinnova Investments, Inc.
13F
Company
0.66%
446,839
$23,669,062 31 Mar 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.66%
445,429
$23,594,374 31 Mar 2025
13F
VOLORIDGE INVESTMENT MANAGEMENT, LLC
13F
Company
0.63%
422,868
$22,399,318 31 Mar 2025
13F
ORBIMED ADVISORS LLC
13F
Company
0.56%
380,000
$20,128,600 31 Mar 2025
13F
BALYASNY ASSET MANAGEMENT L.P.
13F
Company
0.53%
355,712
$18,842,065 31 Mar 2025
13F
SILVERARC CAPITAL MANAGEMENT, LLC
13F
Company
0.5%
337,605
$17,882,937 31 Mar 2025
13F
FRANKLIN RESOURCES INC
13F
Company
0.48%
326,160
$17,276,695 31 Mar 2025
13F
S.c.a. Candriam
13F
Individual
0.43%
291,469
$15,439,113 31 Mar 2025
13F
Siren, L.L.C.
13F
Individual
0.41%
277,533
$14,700,923 31 Mar 2025
13F
UBS Group AG
13F
Company
0.4%
272,108
$14,413,561 31 Mar 2025
13F
Invesco Ltd.
13F
Company
0.39%
261,902
$13,872,949 31 Mar 2025
13F
Pictet Asset Management Holding SA
13F
Company
0.39%
259,346
$13,853,913 31 Mar 2025
13F
COMERICA BANK
13F
Company
0.36%
244,754
$12,964,619 31 Mar 2025
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.32%
217,379
$11,514,566 31 Mar 2025
13F
Qube Research & Technologies Ltd
13F
Company
0.32%
216,193
$11,451,743 31 Mar 2025
13F
Cubist Systematic Strategies, LLC
13F
Company
0.26%
173,822
$9,207,355 31 Mar 2025
13F
Cormorant Asset Management, LP
13F
Company
0.22%
150,000
$7,945,500 31 Mar 2025
13F
Nuveen, LLC
13F
Company
0.22%
147,301
$7,802,534 31 Mar 2025
13F
Bank of New York Mellon Corp
13F
Company
0.22%
146,585
$7,764,607 31 Mar 2025
13F
JPMORGAN CHASE & CO
13F
Company
0.21%
143,640
$7,608,611 31 Mar 2025
13F
PANAGORA ASSET MANAGEMENT INC
13F
Company
0.21%
141,162
$7,477,351 31 Mar 2025
13F
Samsara BioCapital, LLC
13F
Company
0.21%
138,118
$7,316,110 31 Mar 2025
13F
LORD, ABBETT & CO. LLC
13F
Company
0.2%
135,360
$7,170,000 31 Mar 2025
13F

Institutional Holders of RHYTHM PHARMACEUTICALS, INC. - Common Stock (RYTM) as of Q2 2025

As of 30 Jun 2025, RHYTHM PHARMACEUTICALS, INC. - Common Stock (RYTM) was held by 225 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 66,543,505 shares. The largest 10 holders included BlackRock, Inc., BAKER BROS. ADVISORS LP, RA CAPITAL MANAGEMENT, L.P., PRIMECAP MANAGEMENT CO/CA/, VANGUARD GROUP INC, NEA Management Company, LLC, PERCEPTIVE ADVISORS LLC, FMR LLC, STATE STREET CORP, and GOLDMAN SACHS GROUP INC. This page lists 224 institutional shareholders reporting positions in this security for the Q2 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q2 2025 vs Q1 2025 Across Filers

Q1 2025 holders
226
Q2 2025 holders
225
Holder diff
-1
Investor Q1 2025 Shares Q2 2025 Shares Share Diff Share Chg % Q1 2025 Value $ Q2 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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