Security key
76243J105
RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM)
CUSIP: 76243J105
Q2 2025 13F Holders as of 30 Jun 2025
- Type / Class
- Equity / Common Stock, $0.001 par value per share
- Shares outstanding
- 69,012,275
- Total 13F shares
- 66,543,505
- Share change
- +1,932,077
- Total reported value
- $4,204,958,379
- Put/Call ratio
- 274%
- Price per share
- $63.19
- Number of holders
- 225
- Value change
- +$136,584,141
- Number of buys
- 125
- Number of sells
- 105
Report period
Q2 2025
Institutions
225
Top holders
10
RYTM full security history
Newer quarter: Q3 2025
Previous quarter: Q1 2025
RHYTHM PHARMACEUTICALS, INC. SEC filings
RHYTHM PHARMACEUTICALS, INC. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 76243J105
Recent filing periods:
Top shareholders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP |
13D/G
13F
|
Company |
8.9%
|
5,604,483
|
$360,984,750 | $0 | 31 Mar 2025 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
6.9%
from 13D/G
|
6,854,755
|
$363,096,374 | — | 31 Mar 2025 | |
| GOLDMAN SACHS GROUP INC |
13D/G
13F
|
THE GOLDMAN SACHS GROUP, INC. · Company |
3%
|
1,818,932
|
$117,157,406 | $0 | 31 Dec 2024 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
|
Company |
8.8%
|
6,084,412
|
$322,291,304 | — | 31 Mar 2025 | |
| PRIMECAP MANAGEMENT CO/CA/ |
13F
|
Company |
8.4%
|
5,787,322
|
$306,554,446 | — | 31 Mar 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
5%
|
3,444,926
|
$182,477,729 | — | 31 Mar 2025 | |
| NEA Management Company, LLC |
13F
|
Company |
4.2%
|
2,909,956
|
$154,140,369 | — | 31 Mar 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
3.7%
|
2,548,445
|
$134,991,132 | — | 31 Mar 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.9%
|
1,970,733
|
$104,389,727 | — | 31 Mar 2025 | |
| FMR LLC |
13F
|
Company |
2.4%
|
1,688,375
|
$89,433,248 | — | 31 Mar 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
2.4%
|
1,655,350
|
$90,747,654 | — | 31 Mar 2025 | |
| FEDERATED HERMES, INC. |
13F
|
Company |
2.3%
|
1,591,871
|
$84,321,407 | — | 31 Mar 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
2.1%
|
1,458,022
|
$77,231,425 | — | 31 Mar 2025 | |
| WESTFIELD CAPITAL MANAGEMENT CO LP |
13F
|
Company |
1.9%
|
1,341,092
|
$71,037,643 | — | 31 Mar 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.9%
|
1,287,168
|
$68,196,935 | — | 31 Mar 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
1.7%
|
1,199,053
|
$63,515,000 | — | 31 Mar 2025 | |
| Checkpoint Capital L.P. |
13F
|
Company |
1.3%
|
907,240
|
$48,056,503 | — | 31 Mar 2025 | |
| Rock Springs Capital Management LP |
13F
|
Company |
1.2%
|
834,188
|
$44,186,938 | — | 31 Mar 2025 | |
| ALKEON CAPITAL MANAGEMENT LLC |
13F
|
Company |
1.2%
|
817,700
|
$43,313,569 | — | 31 Mar 2025 | |
| Frazier Life Sciences Management, L.P. |
13F
|
Company |
0.98%
|
678,760
|
$35,953,917 | — | 31 Mar 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
0.96%
|
659,431
|
$34,930,060 | — | 31 Mar 2025 | |
| LOOMIS SAYLES & CO L P |
13F
|
Company |
0.88%
|
605,764
|
$32,087,000 | — | 31 Mar 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.78%
|
536,206
|
$28,402,833 | — | 31 Mar 2025 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.78%
|
535,103
|
$28,344,405 | — | 31 Mar 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.73%
|
504,049
|
$26,699,494 | — | 31 Mar 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
0.72%
|
500,000
|
$26,485,000 | — | 31 Mar 2025 | |
| Opaleye Management Inc. |
13F
|
Company |
0.71%
|
490,000
|
$25,955,300 | — | 31 Mar 2025 | |
| Sofinnova Investments, Inc. |
13F
|
Company |
0.65%
|
446,839
|
$23,669,062 | — | 31 Mar 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.65%
|
445,429
|
$23,594,374 | — | 31 Mar 2025 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.61%
|
422,868
|
$22,399,318 | — | 31 Mar 2025 | |
| ORBIMED ADVISORS LLC |
13F
|
Company |
0.55%
|
380,000
|
$20,128,600 | — | 31 Mar 2025 | |
| BALYASNY ASSET MANAGEMENT L.P. |
13F
|
Company |
0.52%
|
355,712
|
$18,842,065 | — | 31 Mar 2025 | |
| SILVERARC CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.49%
|
337,605
|
$17,882,937 | — | 31 Mar 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.47%
|
326,160
|
$17,276,695 | — | 31 Mar 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.42%
|
291,469
|
$15,439,113 | — | 31 Mar 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
0.4%
|
277,533
|
$14,700,923 | — | 31 Mar 2025 | |
| UBS Group AG |
13F
|
Company |
0.39%
|
272,108
|
$14,413,561 | — | 31 Mar 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.38%
|
261,902
|
$13,872,949 | — | 31 Mar 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.38%
|
259,346
|
$13,853,913 | — | 31 Mar 2025 | |
| COMERICA BANK |
13F
|
Company |
0.35%
|
244,754
|
$12,964,619 | — | 31 Mar 2025 | |
| NORGES BANK |
13F
|
Company |
0.32%
|
223,484
|
$11,837,947 | — | 31 Mar 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.31%
|
217,379
|
$11,514,566 | — | 31 Mar 2025 | |
| Qube Research & Technologies Ltd |
13F
|
Company |
0.31%
|
216,193
|
$11,451,743 | — | 31 Mar 2025 | |
| Cubist Systematic Strategies, LLC |
13F
|
Company |
0.25%
|
173,822
|
$9,207,355 | — | 31 Mar 2025 | |
| Cormorant Asset Management, LP |
13F
|
Company |
0.22%
|
150,000
|
$7,945,500 | — | 31 Mar 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.21%
|
147,301
|
$7,802,534 | — | 31 Mar 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.21%
|
146,585
|
$7,764,607 | — | 31 Mar 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.21%
|
143,640
|
$7,608,611 | — | 31 Mar 2025 | |
| PANAGORA ASSET MANAGEMENT INC |
13F
|
Company |
0.2%
|
141,162
|
$7,477,351 | — | 31 Mar 2025 | |
| Samsara BioCapital, LLC |
13F
|
Company |
0.2%
|
138,118
|
$7,316,110 | — | 31 Mar 2025 |
Institutional Holders of RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) as of Q2 2025
As of 30 Jun 2025,
RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) was held by
225 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
66,543,505 shares.
The largest 10 holders included
BlackRock, Inc., BAKER BROS. ADVISORS LP, RA CAPITAL MANAGEMENT, L.P., PRIMECAP MANAGEMENT CO/CA/, VANGUARD GROUP INC, NEA Management Company, LLC, PERCEPTIVE ADVISORS LLC, FMR LLC, STATE STREET CORP, and GOLDMAN SACHS GROUP INC.
This page lists
225
institutional shareholders reporting positions in this security
for the Q2 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q2 2025 vs Q1 2025 Across Filers
Q1 2025 holders
226
Q2 2025 holders
225
Holder diff
-1
| Investor | Q1 2025 Shares | Q2 2025 Shares | Share Diff | Share Chg % | Q1 2025 Value $ | Q2 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.