What does CUSIP 76243J105 represent in this 13F holders report?

CUSIP 76243J105 is the security identifier for RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock used to aggregate holder disclosures.

How many institutions held RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock in Q4 2022?

116 institutional investors reported RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock for Q4 2022. Use the holders table for investor-level position and value details.

RHYTHM PHARMACEUTICALS, INC. - Common Stock (RYTM)

CUSIP: 76243J105

Q4 2022 13F Holders as of 31 Dec 2022

Type / Class: Equity / Common Stock
Shares outstanding: 68,385,438
Total 13F shares: 62,378,764
Share change: +2,854,547
Total reported value: $1,816,485,551
Put/Call ratio: 79%
Price per share: $29.12
Number of holders: 116
Value change: +$85,568,575
Number of buys: 66
Number of sells: 37

Quarterly Holders Quick Answers

What is CUSIP 76243J105?
CUSIP 76243J105 identifies RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2023
Previous quarter: Q3 2022

Recent filing periods for CUSIP 76243J105:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
PRIMECAP MANAGEMENT CO/CA/	13F	Company	10%	7,026,892	$172,159,000	—	30 Sep 2022	13F
FEDERATED HERMES, INC.	13F	Company	9.2%	6,306,866	$154,518,000	—	30 Sep 2022	13F
BAKER BROS. ADVISORS LP	13F	Company	8.9%	6,062,702	$148,536,000	—	30 Sep 2022	13F
RA CAPITAL MANAGEMENT, L.P.	13F	Company	8%	5,471,067	$134,041,000	—	30 Sep 2022	13F
GOLDMAN SACHS GROUP INC	13F	Company	7%	4,777,178	$117,040,000	—	30 Sep 2022	13F
NEA Management Company, LLC	13F	Company	7.2%	4,912,306	$108,316,000	—	30 Sep 2022	13F
BlackRock Finance, Inc.	13F	Company	5.2%	3,537,499	$86,667,000	—	30 Sep 2022	13F
STATE STREET CORP	13F	Company	4.6%	3,127,905	$76,634,000	—	30 Sep 2022	13F
VANGUARD GROUP INC	13F	Company	3.3%	2,234,272	$54,739,000	—	30 Sep 2022	13F
Frazier Life Sciences Management, L.P.	13F	Company	2.8%	1,894,000	$46,403,000	—	30 Sep 2022	13F
Rock Springs Capital Management LP	13F	Company	2.6%	1,760,865	$43,141,000	—	30 Sep 2022	13F
ALKEON CAPITAL MANAGEMENT LLC	13F	Company	2.5%	1,705,000	$41,773,000	—	30 Sep 2022	13F
JANUS HENDERSON GROUP PLC	13F	Company	2.3%	1,561,083	$38,247,000	—	30 Sep 2022	13F
FMR LLC	13F	Company	2%	1,370,948	$33,588,000	—	30 Sep 2022	13F
Opaleye Management Inc.	13F	Company	1.2%	810,000	$19,845,000	—	30 Sep 2022	13F
Polar Capital Holdings Plc	13F	Company	1%	714,739	$17,511,000	—	30 Sep 2022	13F
Assenagon Asset Management S.A.	13F	Company	0.69%	470,410	$11,525,000	—	30 Sep 2022	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.57%	388,112	$9,508,000	—	30 Sep 2022	13F
Samsara BioCapital, LLC	13F	Company	0.5%	345,293	$8,460,000	—	30 Sep 2022	13F
CITIGROUP INC	13F	Company	0.4%	272,187	$6,669,000	—	30 Sep 2022	13F
Rafferty Asset Management, LLC	13F	Company	0.38%	262,288	$6,426,000	—	30 Sep 2022	13F
VOLORIDGE INVESTMENT MANAGEMENT, LLC	13F	Company	0.36%	243,408	$5,963,000	—	30 Sep 2022	13F
MORGAN STANLEY	13F	Company	0.34%	230,172	$5,639,000	—	30 Sep 2022	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.33%	223,131	$5,466,000	—	30 Sep 2022	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.32%	218,406	$5,351,000	—	30 Sep 2022	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	0.31%	214,522	$5,256,000	—	30 Sep 2022	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.3%	204,269	$5,005,000	—	30 Sep 2022	13F
Informed Momentum Co LLC	13F	Company	0.29%	198,699	$4,868,000	—	30 Sep 2022	13F
Walleye Capital LLC	13F	Company	0.28%	191,373	$4,689,000	—	30 Sep 2022	13F
Parkman Healthcare Partners LLC	13F	Company	0.27%	187,989	$4,606,000	—	30 Sep 2022	13F
D. E. Shaw & Co., Inc.	13F	Company	0.27%	183,069	$4,485,000	—	30 Sep 2022	13F
RICE HALL JAMES & ASSOCIATES, LLC	13F	Company	0.25%	170,357	$4,174,000	—	30 Sep 2022	13F
Altium Capital Management LLC	13F	Company	0.25%	170,000	$4,165,000	—	30 Sep 2022	13F
BARCLAYS PLC	13F	Company	0.24%	164,353	$4,027,000	—	30 Sep 2022	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	0.22%	153,213	$3,754,000	—	30 Sep 2022	13F
NORTHERN TRUST CORP	13F	Company	0.17%	114,109	$2,796,000	—	30 Sep 2022	13F
Cubist Systematic Strategies, LLC	13F	Company	0.16%	111,511	$2,732,000	—	30 Sep 2022	13F
Swiss National Bank	13F	Company	0.13%	89,600	$2,195,000	—	30 Sep 2022	13F
TUDOR INVESTMENT CORP ET AL	13F	Company	0.12%	83,796	$2,053,000	—	30 Sep 2022	13F
BNP PARIBAS FINANCIAL MARKETS	13F	Company	0.12%	80,933	$1,982,858	—	30 Sep 2022	13F
Prosight Management, LP	13F	Company	0.12%	80,000	$1,960,000	—	30 Sep 2022	13F
Global IMC LLC	13F	Company	0.12%	78,976	$1,935,000	—	30 Sep 2022	13F
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC)	13F	Company	0.11%	72,375	$1,773,000	—	30 Sep 2022	13F
Ghost Tree Capital, LLC	13F	Company	0.1%	65,000	$1,593,000	—	30 Sep 2022	13F
VOYA INVESTMENT MANAGEMENT LLC	13F	Company	0.09%	63,595	$1,558,078	—	30 Sep 2022	13F
Squarepoint Ops LLC	13F	Company	0.08%	57,994	$1,421,000	—	30 Sep 2022	13F
CITADEL ADVISORS LLC	13F	Company	0.08%	55,835	$1,368,000	—	30 Sep 2022	13F
Hennion & Walsh Asset Management, Inc.	13F	Company	0.08%	51,802	$1,269,000	—	30 Sep 2022	13F
Schonfeld Strategic Advisors LLC	13F	Company	0.07%	48,903	$1,198,000	—	30 Sep 2022	13F
Nuveen Asset Management, LLC	13F	Company	0.06%	40,290	$987,000	—	30 Sep 2022	13F

Institutional Holders of RHYTHM PHARMACEUTICALS, INC. - Common Stock (RYTM) as of Q4 2022

As of 31 Dec 2022, RHYTHM PHARMACEUTICALS, INC. - Common Stock (RYTM) was held by 116 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 62,378,764 shares. The largest 10 holders included PRIMECAP MANAGEMENT CO/CA/, BAKER BROS. ADVISORS LP, FEDERATED HERMES, INC., RA CAPITAL MANAGEMENT, L.P., GOLDMAN SACHS GROUP INC, NEA Management Company, LLC, BlackRock Inc., STATE STREET CORP, VANGUARD GROUP INC, and ALKEON CAPITAL MANAGEMENT LLC. This page lists 116 institutional shareholders reporting positions in this security for the Q4 2022 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2022 vs Q3 2022 Across Filers

Q3 2022 holders

Q4 2022 holders

116

Holder diff

Investor	Q3 2022 Shares	Q4 2022 Shares	Share Diff	Share Chg %	Q3 2022 Value $	Q4 2022 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.