RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM)

Q: What does CUSIP 76243J105 represent in this 13F holders report?

CUSIP 76243J105 is the security identifier for RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share used to aggregate holder disclosures.

Q: How many institutions held RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share in Q4 2022?

116 institutional investors reported RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share for Q4 2022. Use the holders table for investor-level position and value details.

CUSIP: 76243J105

Q4 2022 13F Holders as of 31 Dec 2022

Security type / class: Equity / Common Stock, $0.001 par value per share
Total 13F shares: 62,378,764
Total 13F value: $1,816,485,551
Share change: +2,854,547
Put/Call ratio: 79%
SEC-reported price per share: $29.12
Number of holders: 116
Value change: +$85,568,575
Number of buys: 66
Number of sells: 37
Shares outstanding: 69,012,275

Security key

76243J105

Report period

Q4 2022

Institutions

116

Top holders

RYTM full security history Ownership snapshot Full 13F holder table Newer quarter: Q1 2023 Previous quarter: Q3 2022 RHYTHM PHARMACEUTICALS, INC. SEC filings RHYTHM PHARMACEUTICALS, INC. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 76243J105

Newer quarter: Q1 2023 Previous quarter: Q3 2022

Recent filing periods:

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024

Ownership snapshot

Top reported holders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

PRIMECAP MANAGEMENT CO/CA/

Disclosed value leader

PRIMECAP MANAGEMENT CO/CA/

Comparable rows

15/15

Latest evidence

30 Sep 2022

13F Lead comparable stake: 10% Showing 1-6 of 15 holder rows.

Quick read

PRIMECAP MANAGEMENT CO/CA/ leads the comparable SEC ownership view at 10%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens PRIMECAP MANAGEMENT CO/CA/'s linked filing trail.

Comparable ownership Top 5

PRIMECAP MANAGEMENT CO/CA/ 10%

FEDERATED HERMES, INC. 9.1%

BAKER BROS. ADVISORS LP 8.8%

RA CAPITAL MANAGEMENT, L.P. 7.9%

NEA Management Company, LLC 7.1%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
PRIMECAP MANAGEMENT CO/CA/	13F Company 13F	10%	$172,159,000 7,026,892 shares	—	30 Sep 2022
FEDERATED HERMES, INC.	13F Company 13F	9.1%	$154,518,000 6,306,866 shares	—	30 Sep 2022
BAKER BROS. ADVISORS LP	13F Company 13F	8.8%	$148,536,000 6,062,702 shares	—	30 Sep 2022
RA CAPITAL MANAGEMENT, L.P.	13F Company 13F	7.9%	$134,041,000 5,471,067 shares	—	30 Sep 2022
NEA Management Company, LLC	13F Company 13F	7.1%	$108,316,000 4,912,306 shares	—	30 Sep 2022
GOLDMAN SACHS GROUP INC	13F Company 13F	6.9%	$117,040,000 4,777,178 shares	—	30 Sep 2022

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2022

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

116

62,378,764

Rows available

116

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2022 vs Q3 2022 Across Filers

Q3 2022 holders

Q4 2022 holders

116

Holder diff

Investor	Q3 2022 Shares	Q4 2022 Shares	Share Diff	Share Chg %	Q3 2022 value	Q4 2022 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend