BAKER BROS. ADVISORS LP - 31 Mar 2025 SCHEDULE 13G/A Report for Rhythm Pharmaceuticals, Inc. Common Stock, par value $0.001 per share (RYTM)

Filing Manager: BAKER BROS. ADVISORS LP
Reporting Manager: Baker Bros. Advisors LP
Security: Rhythm Pharmaceuticals, Inc. Common Stock, par value $0.001 per share
Symbol: RYTM
Shares outstanding: 63M shares
Disclosed Ownership: 5.6M shares
Ownership: 8.9%
Form type: SCHEDULE 13G/A
Filing time: 15 May 2025, 16:19:29 UTC
Date of event: 31 Mar 2025
SEC: View on sec.gov

Reporting Managers (4)

Name	Ownership	Shares Owned	sole voting power	Signature	Title
Baker Bros. Advisors LP	8.9%	5.6M	5.6M	/s/ Scott L. Lessing	By: Baker Bros. Advisors (GP) LLC, its general partner Scott L. Lessing/ President
Baker Bros. Advisors (GP) LLC	8.9%	5.6M	5.6M	/s/ Scott L. Lessing	Scott L. Lessing/ President
Julian C. Baker	8.9%	5.6M	5.6M	/s/ Julian C. Baker	Julian C. Baker
Felix J. Baker	8.9%	5.6M	5.6M	/s/ Felix J. Baker	Felix J. Baker