Septerna, Inc. - Common Stock (SEPN)

CUSIP: 81734D104

Q3 2026 13F Holders as of 30 Sep 2026

Holder snapshot 6 signals
Share change
+46,211
SEC-reported price per share
$39.13
Number of holders
19
Value change
+$1,808,240
Number of buys
12
Number of sells
1
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
45,097,233

Security key

81734D104

Report period

Q3 2026

Institutions

19

Top holders

10

Ownership snapshot

Top reported holders of SEPN - Septerna, Inc. - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Third Rock Ventures V, L.P.
Disclosed value leader
Third Rock Ventures VI, L.P.
Comparable rows
4/15
Latest evidence
12 Aug 2026
3/4/5 13D/G 13F Lead comparable stake: 14% 11 rows are not safely comparable across share classes. 13D/G row: Third Rock Ventures V, L.P. Showing 1-6 of 15 holder rows.

Quick read

Third Rock Ventures V, L.P. leads the comparable SEC ownership view at 14%.

4 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Third Rock Ventures V, L.P.'s linked filing trail.
Comparable ownership Top 4
Third Rock Ventures V, L.P. 14%
RA CAPITAL MANAGEMENT, L.P. 12%
DRIEHAUS CAPITAL MANAGEMENT LLC 9.8%
BIOTECHNOLOGY VALUE FUND L P 3.8%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Third Rock Ventures V, L.P.
3/4/5 13D/G
10%+ Owner
14%
Reported 13D/G · 31 Mar 2025
$469,463,739
13,432,506 shares
mixed-class rows
+$7,399,858 12 Aug 2026
RA CAPITAL MANAGEMENT, L.P.
13F 13D/G 3/4/5
Company · Director, 10%+ Owner
12%
Reported 13D/G · 12 Aug 2026
$234,291,284
6,995,858 shares
— 30 Jun 2026
DRIEHAUS CAPITAL MANAGEMENT LLC
13D/G 13F
Company
9.8%
Reported 13D/G · 30 Jun 2026
$148,463,112
4,433,058 shares
-$7,597,307 30 Jun 2026
BIOTECHNOLOGY VALUE FUND L P
13D/G
BVF PARTNERS L P/IL
3.8%
Reported 13D/G · 31 Dec 2025
$42,813,056
1,720,782 shares
-$66,562,509 31 Dec 2025
Third Rock Ventures VI, L.P.
3/4/5
10%+ Owner
—
mixed-class rows
$488,309,201
16,495,641 shares
mixed-class rows
+$7,399,858 12 Aug 2026
Third Rock Ventures GP V, LP
3/4/5
10%+ Owner
—
denominator unverified
$451,021,871
10,280,050 shares
+$7,399,858 12 Aug 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q3 2026

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
19
Shares
86,718
Rows available
19
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q3 2026 vs Q2 2026 Across Filers

Q2 2026 holders
153
Q3 2026 holders
19
Holder diff
-134
Investor Q2 2026 Shares Q3 2026 Shares Share Diff Share Chg % Q2 2026 value Q3 2026 value Value change Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. Manage preferences to update or revoke optional consent for future visits. For more information, see our Privacy Policy .