Septerna, Inc. - Common Stock, $0.001 par value per share (SEPN)

CUSIP: 81734D104

Q4 2024 13F Holders as of 31 Dec 2024

Type / Class
Equity / Common Stock, $0.001 par value per share
Shares outstanding
45,283,737
Total 13F shares
44,129,388
Share change
+33,632,096
Total reported value
$1,010,571,873
Price per share
$22.90
Number of holders
71
Value change
+$770,183,886
Number of buys
66

Security key

81734D104

Report period

Q4 2024

Institutions

71

Top holders

10

Top shareholders of SEPN - Septerna, Inc. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
Third Rock Ventures V, L.P.
3/4/5
10%+ Owner
class O/S missing
9,368,047
$54,803,075 28 Oct 2024
Ran Xiao
3/4/5
Interim CFO
class O/S missing
58,069
$339,704 24 Oct 2024

Institutional Holders of Septerna, Inc. - Common Stock, $0.001 par value per share (SEPN) as of Q4 2024

As of 31 Dec 2024, Septerna, Inc. - Common Stock, $0.001 par value per share (SEPN) was held by 71 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 44,129,388 shares. The largest 10 holders included RA CAPITAL MANAGEMENT, L.P., TRV GP V, LLC, TRV GP VI, LLC, Samsara BioCapital, LLC, Driehaus Capital Management LLC, BVF INC/IL, Siren, L.L.C., Deep Track Capital, LP, BlackRock, Inc., and GOLDMAN SACHS GROUP INC. This page lists 71 institutional shareholders reporting positions in this security for the Q4 2024 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q4 2024 vs Q4 2025 Across Filers

Q4 2025 holders
123
Q4 2024 holders
71
Holder diff
-52
Investor Q4 2025 Shares Q4 2024 Shares Share Diff Share Chg % Q4 2025 Value $ Q4 2024 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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