Type / Class
Equity / Common Stock, $0.001 par value per share
Shares outstanding
45,283,737
Total 13F shares
45,591,200
Share change
+812,198
Total reported value
$1,270,965,588
Put/Call ratio
221%
Price per share
$27.88
Number of holders
123
Value change
+$27,717,426
Number of buys
72
Number of sells
32

Institutional Holders of Septerna, Inc. - Common Stock, $0.001 par value per share (SEPN) as of Q4 2025

As of 31 Dec 2025, Septerna, Inc. - Common Stock, $0.001 par value per share (SEPN) was held by 123 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 45,591,200 shares. The largest 10 holders included RA CAPITAL MANAGEMENT, L.P., TRV GP V, LLC, Driehaus Capital Management LLC, TRV GP VI, LLC, SAMSARA BIOCAPITAL, LLC, GOLDMAN SACHS GROUP INC, Siren, L.L.C., BlackRock, Inc., BVF INC/IL, and VANGUARD GROUP INC. This page lists 123 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.