BIOTECHNOLOGY VALUE FUND L P - 31 Dec 2025 SCHEDULE 13G/A Report for Septerna, Inc. Common Stock, $0.001 par value per share (SEPN)

Filing Manager
BIOTECHNOLOGY VALUE FUND L P
Reporting Manager
BVF PARTNERS L P/IL
Security
Septerna, Inc. Common Stock, $0.001 par value per share
Symbol
SEPN
Shares outstanding
45,283,737 shares
Disclosed Ownership
1,720,782 shares
Ownership
3.8%
Form type
SCHEDULE 13G/A
Filing time
17 Feb 2026, 16:25:13 UTC
Date of event
31 Dec 2025
Previous filing
15 May 2025
SEC
View on sec.gov

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Quoteable Key Fact

"BIOTECHNOLOGY VALUE FUND L P disclosed 3.8% ownership in Septerna, Inc. Common Stock, $0.001 par value per share (SEPN) on 31 Dec 2025."

Quick Takeaways

  • BIOTECHNOLOGY VALUE FUND L P filed SCHEDULE 13G/A for Septerna, Inc. Common Stock, $0.001 par value per share (SEPN).
  • Disclosed ownership: 3.8%.
  • Date of event: 31 Dec 2025.

What Changed

  • Previous schedule filing date: 15 May 2025.
  • Current filing was accepted on 17 Feb 2026, 16:25.

Why This Matters

  • This page explains what this Schedule 13D/13G filing tells you before manager-level rows.
  • You can verify ownership claims directly against the original SEC filing.

Official SEC Source

Backed by Schedule 13D/13G

Beneficial ownership values are sourced from the original SEC Schedule 13D/13G filing.

See Original Filing

Reporting Managers (10)

Name Ownership Shares Owned sole voting power shared voting power Signature Title CIK
BIOTECHNOLOGY VALUE FUND L P 2% 919,814 0 919,814 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
BVF I GP LLC 2% 919,814 0 919,814 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
BIOTECHNOLOGY VALUE FUND II LP 1.5% 671,492 0 671,492 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
BVF II GP LLC 1.5% 671,492 0 671,492 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
Biotechnology Value Trading Fund OS LP 0.2% 104,119 0 104,119 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
BVF Partners OS Ltd. 0.2% 104,119 0 104,119 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
BVF GP HOLDINGS LLC 3.6% 1,591,306 0 1,591,306 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
BVF PARTNERS L P/IL 3.8% 1,720,782 0 1,720,782 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
BVF INC/IL 3.8% 1,720,782 0 1,720,782 /s/ Mark N. Lampert Mark N. Lampert, Authorized Signatory
LAMPERT MARK N 3.8% 1,720,782 0 1,720,782 /s/ Mark N. Lampert Mark N. Lampert

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