Security key
81734D104
Septerna, Inc. - Common Stock, $0.001 par value per share (SEPN)
CUSIP: 81734D104
Q3 2025 13F Holders as of 30 Sep 2025
- Security type / class
- Equity / Common Stock, $0.001 par value per share
- Total 13F shares
- 44,549,033
- Total 13F value
- $837,968,810
- Share change
- +129,203
- Put/Call ratio
- 778%
- SEC-reported price per share
- $18.81
- Number of holders
- 82
- Value change
- +$6,406,374
- Number of buys
- 40
- Number of sells
- 33
- Shares outstanding
- 45,283,737
Holder snapshot
7 signals
Open additional details 1 more signal available
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q3 2025
Institutions
82
Top holders
10
SEPN full security history
Ownership snapshot
Full 13F holder table
Newer quarter: Q2 2026
Septerna, Inc. SEC filings
Septerna, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 81734D104
Recent filing periods:
Ownership snapshot
Top reported holders of SEPN - Septerna, Inc. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
Third Rock Ventures V, L.P.
Disclosed value leader
RA CAPITAL MANAGEMENT, L.P.
Comparable rows
15/15
Latest evidence
30 Jun 2025
3/4/5
13D/G
13F
Lead comparable stake: 14%
13D/G row: Third Rock Ventures V, L.P.
Showing 1-6 of 15 holder rows.
Quick read
Third Rock Ventures V, L.P. leads the comparable SEC ownership view at 14%.
15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens Third Rock Ventures V, L.P.'s linked filing trail.
Comparable ownership
Top 5
Third Rock Ventures V, L.P.
14%
DRIEHAUS CAPITAL MANAGEMENT LLC
10%
RA CAPITAL MANAGEMENT, L.P.
15%
TRV GP V, LLC
14%
BVF INC/IL
9.7%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-6 of 15 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Third Rock Ventures V, L.P. |
3/4/5
13D/G
10%+ Owner
|
14%
from 13D/G
|
$54,803,075
9,368,047 shares
|
— | 28 Oct 2024 |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
13D/G
Company
|
10%
from 13D/G
|
$49,472,156
4,680,431 shares
|
— | 30 Jun 2025 |
| RA CAPITAL MANAGEMENT, L.P. |
13F
Company
|
15%
|
$73,946,219
6,995,858 shares
|
— | 30 Jun 2025 |
| TRV GP V, LLC |
13F
Company
|
14%
|
$65,698,797
6,215,591 shares
|
— | 30 Jun 2025 |
| BVF INC/IL |
13F
Company
|
9.7%
|
$46,467,031
4,396,124 shares
|
— | 30 Jun 2025 |
| TRV GP VI, LLC |
13F
Company
|
9.3%
|
$44,517,236
4,211,659 shares
|
— | 30 Jun 2025 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q3 2025
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
82
Shares
44,549,033
Rows available
82
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
89
Q3 2025 holders
82
Holder diff
-7
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 value | Q3 2025 value | Value change | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend