Septerna, Inc. financial metrics

Professional SEC-based dashboard for profitability, financial health, and growth with transparent scoring logic. Latest period: Q1 2026.

Symbol
SEPN on Nasdaq
Location
South San Francisco, CA
Fiscal year end
31 December
Latest financial report
09 Mar 2026

Shareable Research Card

SEPN - Septerna, Inc. Financial Facts

SEPN - Septerna, Inc. has a source-backed company facts page for reviewing reported financial metrics, periods, and linked metric histories.

Start with the latest metric summary, then open metric histories or cross-company rankings to compare the same SEC-backed facts.

Context
Latest metrics period: Q1 2026
Latest reported value
Return On Equity -12%

Based on company facts extracted from SEC 10-Q/10-K XBRL filings where available. Open metric pages to inspect the reported history.

Quick Takeaways

  • SEPN - Septerna, Inc. financial facts are built from SEC company filings data.
  • Latest metrics period on this page: Q1 2026.
  • Headline metric: Return On Equity -12%.

What Changed

  • Return On Equity YoY change: <span class="text-red-600">-68%</span>.
  • Most recent SEC facts end date: 02 Mar 2026.

Why This Matters

  • This gives a beginner-friendly first read before you inspect detailed formulas and metric tables.
  • Every metric card links to a deeper SEC-backed history page for verification.

Source Evidence

Based on latest 10-Q/10-K

Based on company facts extracted from SEC 10-Q/10-K XBRL filings where available. Open company facts to inspect the reported metric history.

See Original Filing

Latest SEC snapshot (2026-03-02) highlights Return On Equity -12.2%, Return On Assets -9.6%, and Operating Margin -66.4%.

Compare This Company Through SEC-backed Metrics

Use these links to compare SEPN - Septerna, Inc. against other SEC filers on the same metric, then verify the company history from the paired facts page.

Financial Quality Score

Transparent 0-100 scoring model based on profitability, financial health, and growth factors.

47.1/100

Caution Confidence high

Return On Equity

-12%

Metric score 0.0/100

Return On Assets

-9.6%

Metric score 0.0/100

Financial Health

Current Ratio
4.73x
Quick Ratio
4.66x
Debt to Equity
0.06x

Strengths

Debt-to-equity, Revenues YoY, and NetIncomeLoss YoY

Watchpoints

Return On Equity, Return On Assets, and Operating Margin

Key metrics snapshot

Return On Equity

-12%

YoY: -68%

Industry median: -43% (n=675)

View history

Return On Assets

-9.6%

YoY: -62%

Industry median: -47% (n=673)

View history

Operating Margin

-66%

YoY: -98%

Industry median: -121% (n=298)

View history

Current Ratio

4.73x

YoY: -83%

Industry median: 3.39x (n=667)

View history

Quick Ratio

4.66x

YoY: -92%

Industry median: 1.51x (n=289)

View history

Debt-to-equity

0.06x

YoY:

Industry median: 0.26x (n=530)

View history

Revenues YoY

4175%

YoY:

Industry median: 7.3% (n=302)

View history

NetIncomeLoss YoY

32%

YoY:

Industry median: -0.93% (n=641)

View history

Profitability

Metric Latest value YoY change
Return On Equity -12% -68%
Return On Assets -9.6% -62%
Operating Margin -66% -98%

Financial Health

Metric Latest value YoY change
Current Ratio 4.73x -83%
Quick Ratio 4.66x -92%
Debt-to-equity 0.06x

Growth

Metric Latest value YoY change
Revenues YoY 4175%
NetIncomeLoss YoY 32%

Share Metrics

Metric Latest value YoY change
Entity Common Stock, Shares Outstanding 44,906,374 +1%

How we score

This score is transparent and deterministic. We weight profitability, financial health, and growth metrics, then renormalize weights when SEC data is missing.

Metric Weight V1 threshold
ROIC205% to 20%
ROE158% to 25%
ROA102% to 10%
Operating Margin55% to 25%
Current Ratio121.0x to 2.0x
Quick Ratio80.8x to 1.5x
Debt to Equity100.3x to 2.0x (lower is better)
Revenue YoY10-10% to +20%
Net Income YoY10-10% to +20%

How Calculated (standard_v1)

Metrics are computed with a market-consensus convention designed for cross-portal comparability.

  • TTM Operating Income / TTM Revenues
  • Current Assets / Current Liabilities (latest instant quarter)
  • (Current Assets - Inventory) / Current Liabilities; fallback: (Cash+Short-Term Investments + Accounts Receivable) / Current Liabilities
  • Total Debt / Stockholders Equity (latest instant quarter; shared unit; freshest series)
  • TTM Net Income / Average Equity (current quarter + same quarter previous year) / 2
  • TTM Net Income / Average Assets (current quarter + same quarter previous year) / 2
  • TTM NOPAT / Average Invested Capital, where NOPAT=Operating Income*(1-tax rate), Invested Capital=Equity+Total Debt-Cash & ST Investments
  • TTM Revenues YoY
  • TTM Net Income YoY