13F Filings History of L.L.C. Siren

Latest 13F report
Q4 2025 - 13 Feb 2026
Value $
$3,352,424,599
Signature - Title
Raymond Debbane - President
Location
Greenwich, CT
Summary
This page shows a list of all the recent 13F filings made by L.L.C. Siren. Form 13F is required to be filed within 45 days of the end of a calendar quarter. L.L.C. Siren reported 113 stock holdings with total value $3,352,424,599 as of Q4 2025. Top holdings included SRRK, KYMR, ONC, EWTX, and RVMD.

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Holdings Value
Quarter Holdings Value $ Bought Sold Net Top Holdings Form Type Filing Time
Q4 2025 113 $3,352,424,599 +$616,013,790 -$402,720,859 +$213,292,931 SRRK, KYMR, ONC, EWTX, RVMD 13F-HR 13 Feb 2026, 10:16
Q3 2025 115 $2,556,293,148 +$279,194,732 -$214,328,056 +$64,866,676 SRRK, KYMR, ONC, ARWR, BCAX 13F-HR 13 Nov 2025, 11:06
Q2 2025 110 $1,932,435,966 +$208,494,499 -$221,396,329 -$12,901,830 SRRK, KYMR, ONC, IRON, CRNX 13F-HR 13 Aug 2025, 10:36
Q1 2025 116 $1,772,780,355 +$315,053,015 -$319,363,391 -$4,310,376 SRRK, ONC, KYMR, BPMC, CRNX Restatement 22 May 2025, 18:45
Q4 2024 117 $2,263,301,059 +$418,212,788 -$279,591,231 +$138,621,557 SRRK, ONC, KYMR, APLS, CRNX 13F-HR 14 Feb 2025, 11:06
Q3 2024 109 $1,998,086,577 $0 $0 $0 KYMR, BGNE, SRRK, BCAX, ARGX 13F-HR 13 Nov 2024, 14:52