Security key
76243J105
RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM)
CUSIP: 76243J105
Q1 2026 13F Holders as of 31 Mar 2026
- Type / Class
- Equity / Common Stock, $0.001 par value per share
- Shares outstanding
- 69,012,275
- Total 13F shares
- 73,450,337
- Share change
- +520,140
- Total reported value
- $6,388,306,391
- Put/Call ratio
- 13%
- Price per share
- $86.97
- Number of holders
- 283
- Value change
- -$49,270,895
- Number of buys
- 156
- Number of sells
- 138
Report period
Q1 2026
Institutions
283
Top holders
10
RYTM full security history
Previous quarter: Q4 2025
RHYTHM PHARMACEUTICALS, INC. SEC filings
RHYTHM PHARMACEUTICALS, INC. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 76243J105
Recent filing periods:
Top shareholders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. |
13F
13D/G
|
Company |
9.9%
from 13D/G
|
6,666,837
|
$713,618,232 | — | 31 Dec 2025 | |
| BAKER BROS. ADVISORS LP |
13F
13D/G
|
Company |
8.9%
from 13D/G
|
5,604,483
|
$599,903,860 | — | 31 Dec 2025 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
6.9%
from 13D/G
|
6,297,334
|
$674,066,632 | — | 31 Dec 2025 | |
| PRIMECAP MANAGEMENT CO/CA/ |
13F
13D/G
|
Company |
5.2%
from 13D/G
|
3,478,669
|
$372,356,730 | — | 31 Dec 2025 | |
| PERCEPTIVE ADVISORS LLC |
13D/G
13F
|
Company |
5.1%
|
3,519,626
|
$303,708,528 | -$77,990,196 | 31 Mar 2026 | |
| VANGUARD CAPITAL MANAGEMENT LLC |
13D/G
|
Vanguard Capital Management |
5%
|
3,432,949
|
$298,563,575 | $0 | 31 Mar 2026 | |
| GOLDMAN SACHS GROUP INC |
13F
13D/G
|
Company · THE GOLDMAN SACHS GROUP, INC. |
3%
from 13D/G
|
1,830,866
|
$195,975,896 | — | 31 Dec 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
9%
|
6,210,916
|
$664,816,448 | — | 31 Dec 2025 | |
| NEA Management Company, LLC |
13F
|
Company |
4.2%
|
2,909,956
|
$311,481,690 | — | 31 Dec 2025 | |
| STATE STREET CORP |
13F
|
Company |
3.2%
|
2,198,615
|
$235,339,750 | — | 31 Dec 2025 | |
| FMR LLC |
13F
|
Company |
2.5%
|
1,706,317
|
$182,644,125 | — | 31 Dec 2025 | |
| FEDERATED HERMES, INC. |
13F
|
Company |
2.4%
|
1,623,841
|
$173,815,940 | — | 31 Dec 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2.3%
|
1,560,847
|
$167,074,000 | — | 31 Dec 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
2.1%
|
1,423,989
|
$152,423,883 | — | 31 Dec 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
2%
|
1,375,729
|
$147,282,636 | — | 31 Dec 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
1.9%
|
1,285,222
|
$137,570,163 | — | 31 Dec 2025 | |
| WESTFIELD CAPITAL MANAGEMENT CO LP |
13F
|
Company |
1.8%
|
1,267,158
|
$135,636,592 | — | 31 Dec 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
1.7%
|
1,185,392
|
$126,884,360 | — | 31 Dec 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
1.6%
|
1,126,125
|
$120,591,241 | — | 31 Dec 2025 | |
| Checkpoint Capital L.P. |
13F
|
Company |
1.4%
|
992,200
|
$106,205,088 | — | 31 Dec 2025 | |
| Capital Research Global Investors |
13F
|
Company |
1.4%
|
985,086
|
$105,443,605 | — | 31 Dec 2025 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
1.3%
|
930,233
|
$99,572,140 | — | 31 Dec 2025 | |
| JENNISON ASSOCIATES LLC |
13F
|
Company |
1.3%
|
918,567
|
$98,323,416 | — | 31 Dec 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
1%
|
695,735
|
$74,471,475 | — | 31 Dec 2025 | |
| Rock Springs Capital Management LP |
13F
|
Company |
1%
|
695,010
|
$74,393,870 | — | 31 Dec 2025 | |
| Woodline Partners LP |
13F
|
Company |
1%
|
688,779
|
$73,726,904 | — | 31 Dec 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.94%
|
651,402
|
$69,726,071 | — | 31 Dec 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.9%
|
621,585
|
$66,534,458 | — | 31 Dec 2025 | |
| LORD, ABBETT & CO. LLC |
13F
|
Company |
0.9%
|
619,542
|
$66,316,000 | — | 31 Dec 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.89%
|
614,663
|
$66,186,853 | — | 31 Dec 2025 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.8%
|
549,020
|
$58,767,100 | — | 31 Dec 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.77%
|
532,447
|
$56,993,127 | — | 31 Dec 2025 | |
| Clearbridge Investments, LLC |
13F
|
Company |
0.73%
|
506,109
|
$54,173,872 | — | 31 Dec 2025 | |
| LOOMIS SAYLES & CO L P |
13F
|
Company |
0.73%
|
503,901
|
$53,937,563 | — | 31 Dec 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
0.72%
|
499,975
|
$53,517,324 | — | 31 Dec 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.71%
|
488,216
|
$52,258,641 | — | 31 Dec 2025 | |
| Integral Health Asset Management, LLC |
13F
|
Company |
0.69%
|
475,000
|
$50,844,000 | — | 31 Dec 2025 | |
| Point72 Asset Management, L.P. |
13F
|
Company |
0.62%
|
429,420
|
$45,965,117 | — | 31 Dec 2025 | |
| UBS Group AG |
13F
|
Company |
0.62%
|
427,236
|
$45,731,342 | — | 31 Dec 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.49%
|
341,193
|
$36,521,299 | — | 31 Dec 2025 | |
| Opaleye Management Inc. |
13F
|
Company |
0.48%
|
330,000
|
$35,323,200 | — | 31 Dec 2025 | |
| Qube Research & Technologies Ltd |
13F
|
Company |
0.45%
|
310,919
|
$33,280,770 | — | 31 Dec 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.44%
|
301,080
|
$32,227,558 | — | 31 Dec 2025 | |
| First Light Asset Management, LLC |
13F
|
Company |
0.43%
|
295,844
|
$31,667,142 | — | 31 Dec 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.42%
|
291,150
|
$31,164,696 | — | 31 Dec 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.42%
|
287,907
|
$30,818,877 | — | 31 Dec 2025 | |
| Sofinnova Investments, Inc. |
13F
|
Company |
0.39%
|
271,394
|
$29,050,014 | — | 31 Dec 2025 | |
| Artisan Partners Limited Partnership |
13F
|
Company |
0.38%
|
263,591
|
$28,214,781 | — | 31 Dec 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.38%
|
261,160
|
$27,954,761 | — | 31 Dec 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
0.36%
|
250,156
|
$26,776,699 | — | 31 Dec 2025 |
Institutional Holders of RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) as of Q1 2026
As of 31 Mar 2026,
RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) was held by
283 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
73,450,337 shares.
The largest 10 holders included
RA CAPITAL MANAGEMENT, L.P., BlackRock, Inc., BAKER BROS. ADVISORS LP, PRIMECAP MANAGEMENT CO/CA/, VANGUARD PORTFOLIO MANAGEMENT LLC, VANGUARD CAPITAL MANAGEMENT LLC, PERCEPTIVE ADVISORS LLC, STATE STREET CORP, GOLDMAN SACHS GROUP INC, and WESTFIELD CAPITAL MANAGEMENT CO LP.
This page lists
283
institutional shareholders reporting positions in this security
for the Q1 2026 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q1 2026 vs Q4 2025 Across Filers
Q4 2025 holders
278
Q1 2026 holders
283
Holder diff
5
| Investor | Q4 2025 Shares | Q1 2026 Shares | Share Diff | Share Chg % | Q4 2025 Value $ | Q1 2026 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.