Security key
05464T104
Axsome Therapeutics, Inc. - Common Stock (AXSM)
CUSIP: 05464T104
Q4 2025 13F Holders as of 31 Dec 2025
- Type / Class
- Equity / Common Stock
- Shares outstanding
- 48,932,355
- Total 13F shares
- 37,608,361
- Share change
- -665,030
- Total reported value
- $6,859,714,741
- Put/Call ratio
- 66%
- Price per share
- $182.64
- Number of holders
- 397
- Value change
- +$13,353,330
- Number of buys
- 204
- Number of sells
- 156
Report period
Q4 2025
Institutions
397
Top holders
10
AXSM full security history
Newer quarter: Q1 2026
Previous quarter: Q3 2025
Axsome Therapeutics, Inc. SEC filings
Axsome Therapeutics, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 05464T104
Recent filing periods:
Top shareholders of AXSM - Axsome Therapeutics, Inc. - Common Stock (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| RTW INVESTMENTS, LP |
13D/G
13F
|
Company |
3.1%
|
1,516,903
|
$165,312,089 | -$153,206,917 | 30 Jun 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
8.5%
|
4,180,646
|
$507,739,457 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
7.7%
|
3,790,929
|
$460,408,328 | — | 30 Sep 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
2.7%
|
1,334,560
|
$162,082,313 | — | 30 Sep 2025 | |
| MACQUARIE GROUP LTD |
13F
|
Company |
2.2%
|
1,084,536
|
$131,717,000 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2.1%
|
1,037,448
|
$125,999,000 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
2%
|
997,700
|
$121,188,899 | — | 30 Sep 2025 | |
| Invesco Ltd. |
13F
|
Company |
2%
|
990,557
|
$120,303,148 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
1.9%
|
942,960
|
$114,522,492 | — | 30 Sep 2025 | |
| FMR LLC |
13F
|
Company |
1.9%
|
927,883
|
$112,691,333 | — | 30 Sep 2025 | |
| Deep Track Capital, LP |
13F
|
Company |
1.8%
|
900,000
|
$109,305,000 | — | 30 Sep 2025 | |
| Fairmount Funds Management LLC |
13F
|
Company |
1.7%
|
815,176
|
$99,003,125 | — | 30 Sep 2025 | |
| EVENTIDE ASSET MANAGEMENT, LLC |
13F
|
Company |
1.5%
|
746,398
|
$90,637,842 | — | 30 Sep 2025 | |
| ALETHEA CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.4%
|
670,883
|
$81,478,740 | — | 30 Sep 2025 | |
| ORBIMED ADVISORS LLC |
13F
|
Company |
1.1%
|
531,800
|
$64,587,110 | — | 30 Sep 2025 | |
| PFM Health Sciences, LP |
13F
|
Company |
1.1%
|
530,332
|
$64,408,821 | — | 30 Sep 2025 | |
| BVF INC/IL |
13F
|
Company |
0.99%
|
486,757
|
$59,116,638 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.91%
|
445,000
|
$54,045,250 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.84%
|
409,580
|
$49,743,576 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.84%
|
409,535
|
$49,738,025 | — | 30 Sep 2025 | |
| Sofinnova Investments, Inc. |
13F
|
Company |
0.8%
|
393,499
|
$47,790,454 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.78%
|
382,047
|
$46,399,608 | — | 30 Sep 2025 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.77%
|
378,024
|
$45,911,016 | — | 30 Sep 2025 | |
| PRINCIPAL FINANCIAL GROUP INC |
13F
|
Company |
0.75%
|
368,434
|
$44,746,308 | — | 30 Sep 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.74%
|
362,138
|
$43,981,660 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.74%
|
361,261
|
$43,875,149 | — | 30 Sep 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
0.74%
|
359,957
|
$43,716,778 | — | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.68%
|
331,864
|
$40,304,883 | — | 30 Sep 2025 | |
| LOOMIS SAYLES & CO L P |
13F
|
Company |
0.67%
|
330,125
|
$40,093,681 | — | 30 Sep 2025 | |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. |
13F
|
Company |
0.67%
|
326,318
|
$39,631,321 | — | 30 Sep 2025 | |
| Qube Research & Technologies Ltd |
13F
|
Company |
0.67%
|
325,626
|
$39,547,278 | — | 30 Sep 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.61%
|
298,341
|
$36,233,515 | — | 30 Sep 2025 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
0.61%
|
296,287
|
$35,984,056 | — | 30 Sep 2025 | |
| Assenagon Asset Management S.A. |
13F
|
Company |
0.6%
|
294,771
|
$35,799,938 | — | 30 Sep 2025 | |
| Tri Locum Partners LP |
13F
|
Company |
0.6%
|
292,137
|
$35,480,039 | — | 30 Sep 2025 | |
| Man Group plc |
13F
|
Company |
0.59%
|
287,908
|
$34,966,427 | — | 30 Sep 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.58%
|
285,598
|
$34,685,878 | — | 30 Sep 2025 | |
| T. Rowe Price Investment Management, Inc. |
13F
|
Company |
0.56%
|
274,014
|
$33,280,000 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.52%
|
253,263
|
$30,758,749 | — | 30 Sep 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.51%
|
250,513
|
$30,424,804 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.46%
|
224,139
|
$27,221,682 | — | 30 Sep 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.46%
|
223,408
|
$27,132,902 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
0.43%
|
212,451
|
$25,802,175 | — | 30 Sep 2025 | |
| Connor, Clark & Lunn Investment Management Ltd. |
13F
|
Company |
0.43%
|
209,069
|
$25,391,430 | — | 30 Sep 2025 | |
| MetLife Investment Management, LLC |
13F
|
Company |
0.4%
|
197,318
|
$23,964,271 | — | 30 Sep 2025 | |
| BNP PARIBAS FINANCIAL MARKETS |
13F
|
Company |
0.39%
|
190,106
|
$23,088,374 | — | 30 Sep 2025 | |
| Rhenman & Partners Asset Management AB |
13F
|
Company |
0.35%
|
172,800
|
$20,986,560 | — | 30 Sep 2025 | |
| RAYMOND JAMES FINANCIAL INC |
13F
|
Company |
0.32%
|
158,689
|
$19,272,778 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.32%
|
158,406
|
$19,238,409 | — | 30 Sep 2025 | |
| Squarepoint Ops LLC |
13F
|
Company |
0.32%
|
155,000
|
$18,824,750 | — | 30 Sep 2025 |
Institutional Holders of Axsome Therapeutics, Inc. - Common Stock (AXSM) as of Q4 2025
As of 31 Dec 2025,
Axsome Therapeutics, Inc. - Common Stock (AXSM) was held by
397 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
37,608,361 shares.
The largest 10 holders included
VANGUARD GROUP INC, BlackRock, Inc., PRICE T ROWE ASSOCIATES INC /MD/, Invesco Ltd., WELLINGTON MANAGEMENT GROUP LLP, FMR LLC, Deep Track Capital, LP, GEODE CAPITAL MANAGEMENT, LLC, NOMURA ASSET MANAGEMENT INTERNATIONAL INC., and STATE STREET CORP.
This page lists
397
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
352
Q4 2025 holders
397
Holder diff
45
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.