Axsome Therapeutics, Inc. - Common Stock (AXSM)

CUSIP: 05464T104

Q4 2025 13F Holders as of 31 Dec 2025

Holder snapshot 7 signals
Share change
-670,066
Put/Call ratio
66%
SEC-reported price per share
$182.64
Number of holders
398
Value change
+$12,741,708
Number of buys
204
Open additional details 1 more signal available
Number of sells
157
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
51,632,132

Security key

05464T104

Report period

Q4 2025

Institutions

398

Top holders

10

Ownership snapshot

Top reported holders of AXSM - Axsome Therapeutics, Inc. - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
RTW INVESTMENTS, LP
Disclosed value leader
VANGUARD GROUP INC
Comparable rows
15/15
Latest evidence
30 Sep 2025
13D/G 13F Lead comparable stake: 3.1% 13D/G row: RTW INVESTMENTS, LP Showing 1-6 of 15 holder rows.

Quick read

RTW INVESTMENTS, LP leads the comparable SEC ownership view at 3.1%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens RTW INVESTMENTS, LP's linked filing trail.
Comparable ownership Top 5
RTW INVESTMENTS, LP 3.1%
VANGUARD GROUP INC 8.1%
BlackRock, Inc. 7.3%
WELLINGTON MANAGEMENT GROUP LLP 2.6%
MACQUARIE GROUP LTD 2.1%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
RTW INVESTMENTS, LP
13D/G 13F
Company
3.1%
$165,312,089
1,516,903 shares
-$153,206,917 30 Jun 2025
VANGUARD GROUP INC
13F
Company
13F
8.1%
$507,739,457
4,180,646 shares
30 Sep 2025
BlackRock, Inc.
13F
Company
13F
7.3%
$460,408,328
3,790,929 shares
30 Sep 2025
WELLINGTON MANAGEMENT GROUP LLP
13F
Company
13F
2.6%
$162,082,313
1,334,560 shares
30 Sep 2025
MACQUARIE GROUP LTD
13F
Company
13F
2.1%
$131,717,000
1,084,536 shares
30 Sep 2025
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
13F
2%
$125,999,000
1,037,448 shares
30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
398
Shares
37,608,367
Rows available
398
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
352
Q4 2025 holders
398
Holder diff
46
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 value Q4 2025 value Value change Value Chg %
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