Holder snapshot 6 signals
Share change
-1,916,852
SEC-reported price per share
$4.46
Number of holders
48
Value change
-$13,260,253
Number of buys
30
Number of sells
18
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
1,373,824

Security key

85209E109

Report period

Q4 2021

Institutions

48

Top holders

10

Ownership snapshot

Top reported holders of SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Novo Holdings A/S
Disclosed value leader
Novo Holdings A/S
Comparable rows
15/15
Latest evidence
30 Sep 2021
13F Lead comparable stake: 329% Showing 1-6 of 15 holder rows.

Quick read

Novo Holdings A/S leads the comparable SEC ownership view at 329%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Novo Holdings A/S's linked filing trail.
Comparable ownership Top 5
Novo Holdings A/S 329%
DEERFIELD MANAGEMENT COMPANY, L.P. 160%
Omega Fund Management, LLC 157%
RiverVest Venture Management LLC 156%
CITADEL ADVISORS LLC 124%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Novo Holdings A/S
13F
Company
13F
329%
$27,131,000
4,514,336 shares
30 Sep 2021
DEERFIELD MANAGEMENT COMPANY, L.P.
13F
Company
13F
160%
$13,222,000
2,200,000 shares
30 Sep 2021
Omega Fund Management, LLC
13F
Company
13F
157%
$12,988,000
2,161,022 shares
30 Sep 2021
RiverVest Venture Management LLC
13F
Company
13F
156%
$12,911
2,148,281 shares
30 Sep 2021
CITADEL ADVISORS LLC
13F
Company
13F
124%
$10,224,000
1,701,076 shares
30 Sep 2021
Rock Springs Capital Management LP
13F
Company
13F
118%
$9,722,000
1,617,601 shares
30 Sep 2021
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2021

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
48
Shares
15,551,600
Rows available
48
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders
42
Q4 2021 holders
48
Holder diff
6
Investor Q3 2021 Shares Q4 2021 Shares Share Diff Share Chg % Q3 2021 value Q4 2021 value Value change Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
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