Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") (SPRB)

Q: What does CUSIP 85209E109 represent in this 13F holders report?

CUSIP 85209E109 is the security identifier for SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") used to aggregate holder disclosures.

Q: How many institutions held SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") in Q4 2024?

30 institutional investors reported SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") for Q4 2024. Use the holders table for investor-level position and value details.

CUSIP: 85209E109

Q4 2024 13F Holders as of 31 Dec 2024

Security type / class: Equity / Common Stock, par value $0.0001 per share (the "Shares")
Total 13F shares: 11,164,918
Total 13F value: $4,686,111
Share change: +502,067
SEC-reported price per share: $0.42
Number of holders: 30
Value change: +$183,106
Number of buys: 10
Number of sells: 14
Shares outstanding: 1,373,824

Security key

85209E109

Report period

Q4 2024

Institutions

Top holders

SPRB full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2025 SPRUCE BIOSCIENCES, INC. SEC filings SPRUCE BIOSCIENCES, INC. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 85209E109

Newer quarter: Q3 2025

Recent filing periods:

Q3 2025

Ownership snapshot

Top reported holders of SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

Novo Holdings A/S

Disclosed value leader

Novo Holdings A/S

Comparable rows

0/15

Latest evidence

10 Dec 2024

3/4/5 13F Highest disclosed value: $1,924,485 15 rows are not safely comparable across share classes. Showing 1-6 of 15 holder rows.

Quick read

Novo Holdings A/S has the largest disclosed position value at $1.92M.

0 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Novo Holdings A/S's linked filing trail.

Disclosed position value Top 5

Novo Holdings A/S $1.92M

RiverVest Venture Management LLC $1.39M

Carlyle Group Inc. $1.32M

Rock Springs Capital Management LP $1.24M

ACADIAN ASSET MANAGEMENT LLC $597K

Value bars compare disclosed positions; verify each figure against the linked filing evidence.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
Novo Holdings A/S	3/4/5 10%+ Owner 3/4/5	— denominator unverified	$1,924,485 2,550,000 shares	—	21 Mar 2024
RiverVest Venture Management LLC	13F Company 13F	— denominator unverified	$1,394,441 2,936,281 shares	—	30 Sep 2024
Carlyle Group Inc.	13F Company 13F	— denominator unverified	$1,321,681 2,896,518 shares	—	30 Sep 2024
Rock Springs Capital Management LP	13F Company 13F	— denominator unverified	$1,239,073 2,609,125 shares	—	30 Sep 2024
ACADIAN ASSET MANAGEMENT LLC	13F Company 13F	— denominator unverified	$597,000 1,259,151 shares	—	30 Sep 2024
VANGUARD GROUP INC	13F Company 13F	— denominator unverified	$400,826 843,844 shares	—	30 Sep 2024

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2024

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

11,164,918

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2024 vs Q3 2024 Across Filers

Q3 2024 holders

Q4 2024 holders

Holder diff

Investor	Q3 2024 Shares	Q4 2024 Shares	Share Diff	Share Chg %	Q3 2024 value	Q4 2024 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend