Comparable stake leader
Orin Hirschman
SEC ownership of SPRUCE BIOSCIENCES, INC.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001683553.
Disclosed value leader
Orin Hirschman
Comparable rows
38/50
Latest evidence
27 Jul 2026
- Public ticker
- SPRB on Nasdaq
- Parsed ownership sources
-
13D/G, 13F, and 3/4/5
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
- Largest SEC-reported holder
-
Orin Hirschman
Ranking: Comparable ownership first, then disclosed value
- Comparable ownership rows
-
38 of 50
Meaning: Rows with safely comparable ownership %
- Latest 13D/G holder
-
Orin Hirschman
Source: Latest parsed Schedule 13D/G stake
- Latest parsed ownership date
-
27 Jul 2026
Freshness: Most recent filing date in this holder set
- Issuer CIK
- 0001683553
- Issuer location
- South San Francisco, CA
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
3 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of SPRUCE BIOSCIENCES, INC. (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
Orin Hirschman
Disclosed value leader
Orin Hirschman
Comparable rows
38/50
Latest evidence
27 Jul 2026
13D/G
13F
3/4/5
Lead comparable stake: 9.1%
12 rows are not safely comparable across share classes.
13D/G row: Orin Hirschman
Showing 1-8 of 50 holder rows.
Quick read
Orin Hirschman leads the comparable SEC ownership view at 9.1%.
38 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens Orin Hirschman's linked filing trail.
Comparable ownership
Top 5
Orin Hirschman
9.1%
BlackRock, Inc.
6.8%
Boone Peter David Mr
6.4%
INTEGRATED CORE STRATEGIES (US) LLC
5.8%
ADAR1 Capital Management, LLC
5.4%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 50 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Orin Hirschman |
13D/G
|
9.1%
|
$13,500,000
250,000 shares
|
$0 | 30 Jun 2026 |
| BlackRock, Inc. |
13D/G
13F
Company
|
6.8%
|
$10,143,144
187,836 shares
|
$0 | 30 Jun 2026 |
| Boone Peter David Mr |
13D/G
|
6.4%
|
$8,045,712
68,184 shares
|
$0 | 21 Nov 2025 |
| INTEGRATED CORE STRATEGIES (US) LLC |
13D/G
|
5.8%
|
$7,788,261
160,981 shares
|
+$2,803,863 | 30 Jun 2026 |
| ADAR1 Capital Management, LLC |
13D/G
13F
Company
|
5.4%
|
$4,796,020
58,000 shares
|
$0 | 31 Dec 2025 |
| CITADEL ADVISORS LLC |
13F
13D/G
Company · Kenneth Griffin
|
5.1%
from 13D/G
|
$4,574,435
69,999 shares
|
— | 31 Mar 2026 |
| Ikarian Capital, LLC |
13F
13D/G
Company
|
4.8%
from 13D/G
|
$7,930,614
121,356 shares
|
— | 31 Mar 2026 |
| Carlyle Group Inc. |
13D/G
13F
The Carlyle Group Inc. · Company
|
4.7%
|
$4,208,342
50,893 shares
|
$0 | 18 Feb 2026 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to buying over the last 12 months. Net value: +$8,298.
Buys
$9,170
Insiders: 1
Sells
$873
Insiders: 1
Net
+$8,298
Shares: +462
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 512
Shares: 50
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 0 | $0 | $0 | $0 |
| 3-6 | 0 | 0 | $0 | $0 | $0 |
| 6-9 | 0 | 0 | $0 | $0 | $0 |
| 9-12 | 512 | 50 | $9,170 | $873 | +$8,298 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-19 of 19 reporting-owner rows connected to SPRUCE BIOSCIENCES, INC.. Open a relationship link for the CIK-to-CIK filing trail.
Rows
19
Largest Forms 3/4/5 holder
Novo Holdings A/S
Net 12M change
+$8,298
Latest report
27 Jul 2026
Recent insider transactions for SPRUCE BIOSCIENCES, INC.
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Adrian W. Quartel | SPRB | Restricted Stock Units | Award | 13,000 | 13,000 | 27 Jul 2026 | Direct | |||
| Javier B. Szwarcberg | SPRB | Common Stock | Award | 1.4% | 266 | 19,270 | 30 Jun 2026 | Direct | ||
| Daniel K. Spiegelman | SPRB | Stock Option (Right to Buy) | Award | 1,700 | 1,700 | 21 May 2026 | Direct | |||
| Camilla Simpson V | SPRB | Stock Option (Right to Buy) | Award | 1,700 | 1,700 | 21 May 2026 | Direct | |||
| Michael G. Grey | SPRB | Stock Option (Right to Buy) | Award | 1,700 | 1,700 | 21 May 2026 | Direct | |||
| Percival Barretto-Ko | SPRB | Stock Option (Right to Buy) | Award | 1,700 | 1,700 | 21 May 2026 | Direct | |||
| Keli Walbert | SPRB | Stock Option (Right to Buy) | Award | 1,700 | 1,700 | 21 May 2026 | Direct | |||
| Corwin Dale Hooks | SPRB | Restricted Stock Units | Award | 11,000 | 11,000 | 09 Mar 2026 | Direct | |||
| Javier B. Szwarcberg | SPRB | Common Stock | Award | 32.8% | 4,690 | 19,004 | 31 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Common Stock | Tax liability | -4.36% | -362 | 7,934 | 15 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Common Stock | Options Exercise | 13.6% | 1,009 | 8,447 | 15 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Restricted Stock Units | Options Exercise | -67% | -1,009 | 497 | 15 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Common Stock | Tax liability | -9.01% | -1,360 | 13,726 | 15 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Common Stock | Options Exercise | 21.8% | 2,676 | 14,922 | 15 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Restricted Stock Units | Options Exercise | -64.4% | -2,676 | 1,480 | 15 Dec 2025 | Direct | ||
| Kirk Ways | SPRB | Common Stock | Options Exercise | 1,250 | 1,250 | 11 Dec 2025 | Direct | |||
| Kirk Ways | SPRB | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -666 | 0 | 11 Dec 2025 | Direct | ||
| Kirk Ways | SPRB | Stock Option (Right to Buy) | Award | 666 | 400 | 11 Dec 2025 | Direct | |||
| Kirk Ways | SPRB | Restricted Stock Units | Options Exercise | -25% | -1,250 | 3,750 | 11 Dec 2025 | Direct | ||
| Kirk Ways | SPRB | Restricted Stock Units | Award | 5,000 | 5,000 | 11 Dec 2025 | Direct | |||
| Javier B. Szwarcberg | SPRB | Employee Stock Option (right to buy) | Disposed to Issuer | -100% | -1,666 | 0 | 11 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Employee Stock Option (right to buy) | Award | 1,666 | 1,666 | 11 Dec 2025 | Direct | |||
| Daniel K. Spiegelman | SPRB | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -946 | 0 | 11 Dec 2025 | Direct | ||
| Daniel K. Spiegelman | SPRB | Stock Option (Right to Buy) | Award | 946 | 458 | 11 Dec 2025 | Direct | |||
| Michael G. Grey | SPRB | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -4,340 | 0 | 11 Dec 2025 | Direct | ||
| Michael G. Grey | SPRB | Stock Option (Right to Buy) | Award | 4,340 | 1,499 | 11 Dec 2025 | Direct | |||
| Samir M. Gharib | SPRB | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -6,131 | 0 | 11 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Stock Option (Right to Buy) | Award | 6,131 | 1,933 | 11 Dec 2025 | Direct | |||
| Javier B. Szwarcberg | SPRB | Employee Stock Option (right to buy) | Disposed to Issuer | -100% | -10,000 | 0 | 11 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Employee Stock Option (right to buy) | Award | 10,000 | 10,000 | 11 Dec 2025 | Direct | |||
| Camilla Simpson V | SPRB | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -1,377 | 0 | 11 Dec 2025 | Direct | ||
| Camilla Simpson V | SPRB | Stock Option (Right to Buy) | Award | 1,377 | 400 | 11 Dec 2025 | Direct | |||
| Percival Barretto-Ko | SPRB | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -800 | 0 | 11 Dec 2025 | Direct | ||
| Percival Barretto-Ko | SPRB | Stock Option (Right to Buy) | Award | 800 | 800 | 11 Dec 2025 | Direct | |||
| Keli Walbert | SPRB | Stock Option (Right to Buy) | Award | 3,400 | 3,400 | 11 Dec 2025 | Direct | |||
| Samir M. Gharib | SPRB | Common Stock | Tax liability | -8.2% | -680 | 7,616 | 11 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Common Stock | Options Exercise | 29.7% | 1,900 | 8,296 | 11 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Restricted Stock Units | Options Exercise | -25% | -1,900 | 5,700 | 11 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Restricted Stock Units | Award | 7,600 | 7,600 | 11 Dec 2025 | Direct | |||
| Javier B. Szwarcberg | SPRB | Common Stock | Tax liability | -14.4% | -2,194 | 12,998 | 11 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Common Stock | Options Exercise | 48.3% | 4,950 | 15,192 | 11 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Restricted Stock Units | Options Exercise | -25% | -4,950 | 14,850 | 11 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Restricted Stock Units | Award | 19,800 | 19,800 | 11 Dec 2025 | Direct | |||
| Samir M. Gharib | SPRB | Common Stock | Tax liability | -2.8% | -184 | 6,396 | 10 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Common Stock | Options Exercise | 8.47% | 514 | 6,580 | 10 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Restricted Stock Units | Options Exercise | -25% | -514 | 1,539 | 10 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Common Stock | Tax liability | -4.01% | -428 | 10,242 | 10 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Common Stock | Options Exercise | 12.6% | 1,196 | 10,670 | 10 Dec 2025 | Direct | ||
| Javier B. Szwarcberg | SPRB | Restricted Stock Units | Options Exercise | -25% | -1,196 | 3,588 | 10 Dec 2025 | Direct | ||
| Samir M. Gharib | SPRB | Common Stock | Tax liability | -9.83% | -661 | 6,066 | 20 Oct 2025 | Direct |
* marks a reported price that did not pass the local price check.