Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") (SPRB)

Q: What does CUSIP 85209E109 represent in this 13F holders report?

CUSIP 85209E109 is the security identifier for SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") used to aggregate holder disclosures.

Q: How many institutions held SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") in Q1 2024?

49 institutional investors reported SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") for Q1 2024. Use the holders table for investor-level position and value details.

CUSIP: 85209E109

Q1 2024 13F Holders as of 31 Mar 2024

Security type / class: Equity / Common Stock, par value $0.0001 per share (the "Shares")
Total 13F shares: 17,968,530
Total 13F value: $14,122,228
Share change: -14,287,876
Put/Call ratio: 98%
SEC-reported price per share: $0.79
Number of holders: 49
Value change: -$48,624,275
Number of buys: 31
Number of sells: 20
Shares outstanding: 1,373,824

Security key

85209E109

Report period

Q1 2024

Institutions

Top holders

SPRB full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2025 SPRUCE BIOSCIENCES, INC. SEC filings SPRUCE BIOSCIENCES, INC. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 85209E109

Newer quarter: Q3 2025

Recent filing periods:

Q3 2025

Ownership snapshot

Top reported holders of SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

Novo Holdings A/S

Disclosed value leader

Novo Holdings A/S

Comparable rows

15/15

Latest evidence

31 Dec 2023

13F 3/4/5 Lead comparable stake: 489% Showing 1-6 of 15 holder rows.

Quick read

Novo Holdings A/S leads the comparable SEC ownership view at 489%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Novo Holdings A/S's linked filing trail.

Comparable ownership Top 5

Novo Holdings A/S 489%

RiverVest Venture Management LLC 214%

Carlyle Group Inc. 211%

Rock Springs Capital Management LP 190%

5AM Venture Management, LLC 172%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
Novo Holdings A/S	13F 3/4/5 Company · 10%+ Owner 13F 3/4/5	489%	$19,696,444 6,722,336 shares	—	31 Dec 2023
RiverVest Venture Management LLC	13F Company 13F	214%	$8,603,304 2,936,281 shares	—	31 Dec 2023
Carlyle Group Inc.	13F Company 13F	211%	$8,370,937 2,896,518 shares	—	31 Dec 2023
Rock Springs Capital Management LP	13F Company 13F	190%	$7,644,736 2,609,125 shares	—	31 Dec 2023
5AM Venture Management, LLC	13F Company 13F	172%	$6,926,520 2,364,000 shares	—	31 Dec 2023
ARMISTICE CAPITAL, LLC	13F Company 13F	162%	$6,533,900 2,230,000 shares	—	31 Dec 2023

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q1 2024

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

17,968,530

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q1 2024 vs Q1 2024 Across Filers

Q1 2024 holders

Holder diff

Investor	Q1 2024 Shares	Q1 2024 Shares	Share Diff	Share Chg %	Q1 2024 value	Q1 2024 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend