Latest Period
Q1 2026
Security Snapshot
SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share (SPRB) Institutional Ownership
CUSIP: 85209E208
13F Institutional Holders and Ownership History from Q3 2025 to Q1 2026
Institutions Reporting
32
Shares (Excl. Options)
739,765
Price
$65.35
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- Security type / class
- Equity / Common Stock, par value $0.0001 per share
- Symbol
- SPRB on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 739,765
- Total 13F value
- $48,344,484
- Portfolio coverage rank
- 0%
- Share change
- -18,520
- Value change
- -$3,009,590
- Number of holders
- 32
- Shares outstanding
- 1,373,497
- SEC-reported price per share
- $51.52
- Insider filing price
- $51.52
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- SPRB - SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share is tracked under CUSIP 85209E208.
- 32 institutions reported positions in Q1 2026.
- 10 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 32 to 32 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $65,599,507 to $48,344,484.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 32 institutions filings for Q1 2026.
Security key
85209E208
Latest holder period
Q1 2026
13F holders
32
13D/G owners
10
CIK / CUSIP context first
Open Q1 2026 holders
SPRB full holder history
SPRUCE BIOSCIENCES, INC. SEC filings
SPRUCE BIOSCIENCES, INC. company facts
SPRUCE BIOSCIENCES, INC. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 85209E208:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
10
Security
SPRB
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Ikarian Capital, LLC | 11% | -46% | $1,060,227 | 121,356 | 0% | Ikarian Capital, LLC | 31 Oct 2025 | |
| INTEGRATED CORE STRATEGIES (US) LLC | 9.6% | $8,519,220 | 103,026 | Millennium Management LLC | 17 Feb 2026 | |||
| CITADEL ADVISORS LLC | 6.5% | -35% | $5,707,852 | -$3,228,541 | 70,035 | -36% | Kenneth Griffin | 31 Dec 2025 |
| Boone Peter David Mr | 6.4% | $8,045,712 | 68,184 | Boone Peter David Mr | 21 Nov 2025 | |||
| Alyeska Investment Group, L.P. | 4.5% | -22% | $3,978,332 | 61,670 | 0% | Alyeska Investment Group, L.P. | 31 Mar 2026 | |
| WELLINGTON MANAGEMENT GROUP LLP | 5.5% | $4,804,344 | 58,949 | Wellington Management Group LLP | 31 Dec 2025 | |||
| ADAR1 Capital Management, LLC | 5.4% | $4,796,020 | 58,000 | ADAR1 Capital Management, LLC | 31 Dec 2025 | |||
| Carlyle Group Inc. | 4.7% | $4,208,342 | 50,893 | The Carlyle Group Inc. | 18 Feb 2026 | |||
| HealthCap VIII, L.P. | 3.4% | $335,256 | 36,640 | HealthCap VIII, L.P. | 07 Oct 2025 | |||
| Squadron Capital Management LLC | 0.9% | -80% | $787,022 | -$3,728,678 | 12,200 | -83% | Squadron Master Fund LP | 31 Mar 2026 |
As of 31 Mar 2026, 32 institutional investors reported holding 739,765 shares of SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share (SPRB). This represents 54% of the company’s total 1,373,497 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
54%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Ikarian Capital, LLC | 8.8% | 121,356 | 0% | 1.1% | $7,930,614 |
| MILLENNIUM MANAGEMENT LLC | 8.1% | 111,888 | 0.01% | $7,311,881 | |
| CITADEL ADVISORS LLC | 5.1% | 69,999 | 0% | 0% | $4,574,435 |
| ADAR1 Capital Management, LLC | 4.3% | 58,600 | +1% | 0.23% | $3,829,510 |
| Alyeska Investment Group, L.P. | 3.8% | 51,671 | 0% | 0.01% | $3,376,700 |
| WELLINGTON MANAGEMENT GROUP LLP | 3.6% | 48,796 | -17% | 0% | $3,188,819 |
| BOOTHBAY FUND MANAGEMENT, LLC | 3.1% | 42,080 | -12% | 0.07% | $2,749,928 |
| Balyasny Asset Management L.P. | 2.9% | 40,000 | 0% | 0.01% | $2,614,000 |
| Carlyle Group Inc. | 2.8% | 38,620 | 0% | 0.02% | $2,523,833 |
| Quinn Opportunity Partners LLC | 2% | 26,810 | +18% | 0.09% | $1,752,034 |
| ExodusPoint Capital Management, LP | 1.6% | 22,000 | -13% | 0.01% | $1,437,700 |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.3% | 18,337 | 0% | 0% | $1,198,323 |
| BlackRock, Inc. | 1.2% | 16,938 | 0% | 0% | $1,106,898 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.94% | 12,889 | +1.2% | 0% | $842,729 |
| Squadron Capital Management LLC | 0.89% | 12,200 | -83% | 0.32% | $797,270 |
| DIADEMA PARTNERS LP | 0.73% | 10,000 | 0.29% | $653,500 | |
| STEMPOINT CAPITAL LP | 0.46% | 6,360 | 0.08% | $415,626 | |
| VANGUARD FIDUCIARY TRUST CO | 0.4% | 5,514 | 0% | 0% | $360,340 |
| GOLDMAN SACHS GROUP INC | 0.4% | 5,506 | 0% | $359,817 | |
| STATE STREET CORP | 0.39% | 5,400 | -16% | 0% | $352,890 |
| Resolute Capital Asset Partners LLC | 0.29% | 4,000 | 0% | 0.14% | $261,400 |
| UBS Group AG | 0.29% | 3,919 | -20% | 0% | $256,107 |
| Persistent Asset Partners Ltd | 0.18% | 2,528 | 0.06% | $165,205 | |
| MORGAN STANLEY | 0.1% | 1,415 | +265% | 0% | $92,471 |
| Lion Point Capital, LP | 0.07% | 1,000 | 0% | 0.39% | $65,350 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
3
Latest
Q1 2026
Rows shown
1-3 of 3