| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Ikarian Capital, LLC | 11% | -46% | $1,060,227 | 121,356 | 0% | Ikarian Capital, LLC | 31 Oct 2025 | |
| CITADEL ADVISORS LLC | 10% | $1,359,648 | 109,649 | Citadel Advisors LLC | 09 Oct 2025 | |||
| Squadron Capital Management LLC | 6.6% | $640,500 | 70,000 | Squadron Capital Management LLC | 08 Oct 2025 | |||
| Boone Peter David Mr | 6.4% | $8,045,712 | 68,184 | Boone Peter David Mr | 21 Nov 2025 | |||
| HealthCap VIII, L.P. | 3.4% | $335,256 | 36,640 | HealthCap VIII, L.P. | 07 Oct 2025 |
As of 30 Sep 2025, 9 institutional investors reported holding 2,937,895 shares of SPRUCE BIOSCIENCES, INC. - Common Stok, par value $0.0001 (SPRB). This represents 276% of the company’s total 1,065,375 outstanding shares.
The largest institutional shareholders of SPRUCE BIOSCIENCES, INC. - Common Stok, par value $0.0001 (SPRB) together control 276% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Carlyle Group Inc. | 272% | 2,896,518 | 0.57% | $24,765,229 | |
| Cable Car Capital, LP | 2.5% | 26,666 | 0.1% | $238,661 | |
| Ikarian Capital, LLC | 1.3% | 13,332 | 0.03% | $119,322 | |
| Lion Point Capital, LP | 0.09% | 1,000 | 0.05% | $8,950 | |
| OSAIC HOLDINGS, INC. | 0.01% | 133 | 0% | $931 | |
| UBS Group AG | 0.01% | 132 | 0% | $1,181 | |
| MORGAN STANLEY | 0.01% | 98 | 0% | $878 | |
| CALDWELL SUTTER CAPITAL, INC. | 0% | 13 | 0% | $116 | |
| BANK OF AMERICA CORP /DE/ | 0% | 3 | 0% | $27 |