Latest Period
Q2 2026
Security Snapshot
SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share (SPRB) Institutional Ownership
CUSIP: 85209E208
13F Institutional Holders and Ownership History from Q3 2025 to Q2 2026
Institutions Reporting
63
Shares (Excl. Options)
2,002,949
Price
$54.00
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- Security type / class
- Equity / Common Stock, par value $0.0001 per share
- Symbol
- SPRB on Nasdaq
- All holders as of 30 Jun 2026
- Q2 2026
- Total 13F shares
- 2,002,949
- Total 13F value
- $108,161,532
- Portfolio coverage rank
- 0%
- Share change
- +1,262,731
- Value change
- +$67,448,654
- Number of holders
- 63
- Shares outstanding
- 2,708,680
- SEC-reported price per share
- $41.45
- Insider filing price
- $41.45
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- SPRB - SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share is tracked under CUSIP 85209E208.
- 63 institutions reported positions in Q2 2026.
- 14 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 32 to 63 between Q1 2026 and Q2 2026.
- SEC-reported value moved from $48,344,484 to $108,161,532.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 63 institutions filings for Q2 2026.
Security key
85209E208
Latest holder period
Q2 2026
13F holders
63
13D/G owners
14
CIK / CUSIP context first
Open Q2 2026 holders
SPRB full holder history
SPRUCE BIOSCIENCES, INC. SEC filings
SPRUCE BIOSCIENCES, INC. company facts
SPRUCE BIOSCIENCES, INC. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 85209E208:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
14
Security
SPRB
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| HIRSCHMAN ORIN | 9.1% | $13,500,000 | 250,000 | Orin Hirschman | 30 Jun 2026 | |||
| BlackRock, Inc. | 6.8% | $10,143,144 | 187,836 | BlackRock, Inc. | 30 Jun 2026 | |||
| INTEGRATED CORE STRATEGIES (US) LLC | 5.8% | -38% | $7,788,261 | +$2,803,863 | 160,981 | +56% | Integrated Core Strategies (US) LLC | 30 Jun 2026 |
| AWM Investment Company, Inc. | 5.1% | $7,111,279 | 146,988 | AWM Investment Company, Inc. | 30 Jun 2026 | |||
| ORBIMED ADVISORS LLC | 4.8% | $6,395,836 | 132,200 | OrbiMed Advisors LLC | 30 Jun 2026 | |||
| Ikarian Capital, LLC | 11% | -46% | $1,060,227 | 121,356 | 0% | Ikarian Capital, LLC | 31 Oct 2025 | |
| Boone Peter David Mr | 6.4% | $8,045,712 | 68,184 | Boone Peter David Mr | 21 Nov 2025 | |||
| ADAR1 Capital Management, LLC | 2.5% | -58% | $3,276,148 | +$470,108 | 67,717 | +17% | ADAR1 Capital Management, LLC | 30 Jun 2026 |
| Alyeska Investment Group, L.P. | 4.5% | -22% | $3,978,332 | 61,670 | 0% | Alyeska Investment Group, L.P. | 31 Mar 2026 | |
| WELLINGTON MANAGEMENT GROUP LLP | 5.5% | $4,804,344 | 58,949 | Wellington Management Group LLP | 31 Dec 2025 | |||
| CITADEL ADVISORS LLC | 1.9% | -66% | $2,511,841 | -$876,452 | 51,919 | -26% | Kenneth Griffin | 30 Jun 2026 |
| Carlyle Group Inc. | 4.7% | $4,208,342 | 50,893 | The Carlyle Group Inc. | 18 Feb 2026 | |||
| HealthCap VIII, L.P. | 3.4% | $335,256 | 36,640 | HealthCap VIII, L.P. | 07 Oct 2025 | |||
| Squadron Capital Management LLC | 0.9% | -80% | $787,022 | -$3,728,678 | 12,200 | -83% | Squadron Master Fund LP | 31 Mar 2026 |
As of 30 Jun 2026, 63 institutional investors reported holding 2,002,949 shares of SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share (SPRB). This represents 74% of the company’s total 2,708,680 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
67%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| AIGH Capital Management LLC | 9.2% | 250,000 | 1.2% | $13,500,000 | |
| ORBIMED ADVISORS LLC | 7.4% | 200,000 | 0.2% | $10,800,000 | |
| BlackRock, Inc. | 6.9% | 187,836 | +1009% | 0% | $10,143,144 |
| MILLENNIUM MANAGEMENT LLC | 5.9% | 160,981 | +44% | 0.01% | $8,692,974 |
| Ikarian Capital, LLC | 4.5% | 121,356 | 0% | 1.1% | $6,553,224 |
| VANGUARD CAPITAL MANAGEMENT LLC | 4.4% | 119,331 | +551% | 0% | $6,443,874 |
| Alyeska Investment Group, L.P. | 3% | 81,671 | +58% | 0.01% | $4,410,234 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.6% | 70,548 | +447% | 0% | $3,809,975 |
| ADAR1 Capital Management, LLC | 2.5% | 67,717 | +16% | 0.17% | $3,656,718 |
| Cable Car Capital, LP | 2.2% | 60,000 | 0.07% | $3,240,000 | |
| CITADEL ADVISORS LLC | 1.9% | 51,905 | -26% | 0% | $2,802,870 |
| STATE STREET CORP | 1.9% | 50,450 | +834% | 0% | $2,724,300 |
| BOOTHBAY FUND MANAGEMENT, LLC | 1.6% | 42,080 | 0% | 0.04% | $2,272,320 |
| STEMPOINT CAPITAL LP | 1.5% | 41,388 | +551% | 0.39% | $2,234,952 |
| Eversept Partners, LP | 1.5% | 40,000 | 0.12% | $2,160,000 | |
| Carlyle Group Inc. | 1.4% | 38,620 | 0% | 0.02% | $2,085,493 |
| GOLDMAN SACHS GROUP INC | 1.2% | 32,348 | +488% | 0% | $1,746,792 |
| Affinity Asset Advisors, LLC | 1.1% | 30,000 | 0.08% | $1,620,000 | |
| DIADEMA PARTNERS LP | 1.1% | 30,000 | +200% | 0.61% | $1,620,000 |
| Stonepine Capital Management, LLC | 1.1% | 28,795 | 1.2% | $1,554,930 | |
| Point72 Asset Management, L.P. | 1% | 28,278 | 0% | $1,527,012 | |
| Quinn Opportunity Partners LLC | 0.99% | 26,810 | 0% | 0.07% | $1,447,740 |
| UBS Group AG | 0.86% | 23,381 | +497% | 0% | $1,262,574 |
| ExodusPoint Capital Management, LP | 0.81% | 22,000 | 0% | 0.01% | $1,188,000 |
| NORTHERN TRUST CORP | 0.78% | 21,083 | 0% | $1,138,482 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
4
Latest
Q2 2026
Rows shown
1-4 of 4