Holder snapshot 5 signals
Share change
-8,389,789
SEC-reported price per share
$0.07
Number of holders
3
Value change
-$2,433,360
Number of sells
26
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
1,373,824

Security key

85209E109

Report period

Q2 2025

Institutions

3

Top holders

3

Ownership snapshot

Top reported holders of SPRB - Spruce Biosciences, Inc. - Common Stock, par value $0.0001 per share (the "Shares") (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
RiverVest Venture Fund II...
Disclosed value leader
Carlyle Group Inc.
Comparable rows
15/15
Latest evidence
31 Mar 2025
13D/G 13F Lead comparable stake: 4.2% 13D/G row: RiverVest Venture Fund III, L.P. Showing 1-6 of 15 holder rows.

Quick read

RiverVest Venture Fund III, L.P. leads the comparable SEC ownership view at 4.2%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens RiverVest Venture Fund III, L.P.'s linked filing trail.
Comparable ownership Top 5
RiverVest Venture Fund III, L.P. 4.2%
Carlyle Group Inc. 211%
Rock Springs Capital Management LP 190%
ACADIAN ASSET MANAGEMENT LLC 76%
Ikarian Capital, LLC 73%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
RiverVest Venture Fund III, L.P.
13D/G
John P. McKearn, Ph.D.
4.2%
$140,762
1,759,521 shares
$0 07 Jan 2025
Carlyle Group Inc.
13F
Company
13F
211%
$840,280
2,896,518 shares
31 Mar 2025
Rock Springs Capital Management LP
13F
Company
13F
190%
$756,907
2,609,125 shares
31 Mar 2025
ACADIAN ASSET MANAGEMENT LLC
13F
Company
13F
76%
$301,000
1,045,828 shares
31 Mar 2025
Ikarian Capital, LLC
13F
Company
13F
73%
$290,100
1,000,000 shares
31 Mar 2025
VANGUARD GROUP INC
13F
Company
13F
61%
$244,715
843,844 shares
31 Mar 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q2 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
3
Shares
2,046,828
Rows available
3
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q2 2025 vs Q1 2025 Across Filers

Q1 2025 holders
30
Q2 2025 holders
3
Holder diff
-27
Investor Q1 2025 Shares Q2 2025 Shares Share Diff Share Chg % Q1 2025 value Q2 2025 value Value change Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
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