Latest Period
Q4 2025
Security Snapshot
SERA PROGNOSTICS, INC. - Class A Common Stock, par value $0.0001 per share (SERA) Institutional Ownership
CUSIP: 81749D107
13F Institutional Holders and Ownership History from Q3 2021 to Q1 2026
Institutions Reporting
56
Shares (Excl. Options)
17,640,480
Price
$2.95
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- Type / Class
- Equity / Class A Common Stock, par value $0.0001 per share
- Symbol
- SERA on Nasdaq
- Shares outstanding
- 38,452,198
- Price per share
- $2.22
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 17,640,480
- Total reported value
- $52,067,649
- % of total 13F portfolios
- 0%
- Share change
- -503,358
- Value change
- -$1,545,175
- Number of holders
- 56
- Price from insider filings
- $2.22
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- SERA - SERA PROGNOSTICS, INC. - Class A Common Stock, par value $0.0001 per share is tracked under CUSIP 81749D107.
- 56 institutions reported positions in Q4 2025.
- 5 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 56 to 11 between Q4 2025 and Q1 2026.
- Reported value moved from $52,067,649 to $11,042,321.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 56 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 81749D107?
CUSIP 81749D107 identifies SERA - SERA PROGNOSTICS, INC. - Class A Common Stock, par value $0.0001 per share in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 81749D107:
Significant Owners of SERA PROGNOSTICS, INC. - Class A Common Stock, par value $0.0001 per share (SERA) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 16% | $18,418,870 | 5,498,170 | Baker Bros. Advisors LP | 12 Feb 2025 | |||
| Whetstone Capital Advisors, LLC | 8.6% | -6.7% | $7,341,294 | -$339,269 | 3,306,889 | -4.4% | Whetstone Capital Advisors, LLC | 31 Mar 2026 |
| Chione Ltd | 7.6% | $8,727,926 | 2,605,351 | Chione Ltd. | 11 Feb 2025 | |||
| Aberdeen Group plc | 6.1% | $6,325,722 | 2,227,367 | Aberdeen Group plc | 30 Jun 2025 | |||
| Vivo Capital IX, LLC | 4.5% | $5,528,974 | 1,650,440 | Vivo Capital IX, LLC | 31 Mar 2025 |
As of 31 Dec 2025, 56 institutional investors reported holding 17,640,480 shares of SERA PROGNOSTICS, INC. - Class A Common Stock, par value $0.0001 per share (SERA). This represents 46% of the company’s total 38,452,198 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of SERA PROGNOSTICS, INC. - Class A Common Stock, par value $0.0001 per share (SERA) together control 45% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 14% | 5,498,170 | 0% | 0.09% | $16,219,602 |
| Whetstone Capital Advisors, LLC | 9% | 3,459,713 | -4.8% | 3.2% | $10,206,153 |
| Aberdeen Group plc | 5.9% | 2,279,699 | 0% | 0.01% | $6,725,112 |
| Vivo Capital, LLC | 4.3% | 1,650,440 | 0% | 0.31% | $4,868,798 |
| VANGUARD GROUP INC | 3.2% | 1,239,449 | +1.8% | 0% | $3,656,375 |
| CITADEL ADVISORS LLC | 1.8% | 707,614 | +8.2% | 0% | $2,087,462 |
| CAPTRUST FINANCIAL ADVISORS | 1.4% | 536,766 | -11% | 0% | $1,583,460 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.87% | 334,639 | +1.1% | 0% | $987,474 |
| AWM Investment Company, Inc. | 0.54% | 207,382 | 0% | 0.06% | $611,777 |
| BlackRock, Inc. | 0.49% | 186,751 | +4.3% | 0% | $550,915 |
| STATE STREET CORP | 0.32% | 124,792 | 0% | 0% | $368,136 |
| MILLENNIUM MANAGEMENT LLC | 0.29% | 113,178 | -11% | 0% | $333,875 |
| GSA CAPITAL PARTNERS LLP | 0.28% | 107,235 | +64% | 0.03% | $316,000 |
| Corient Private Wealth LLC | 0.26% | 100,000 | 0% | 0% | $290,000 |
| NORTHERN TRUST CORP | 0.25% | 96,535 | +9.1% | 0% | $284,778 |
| MORGAN STANLEY | 0.21% | 80,968 | -3.6% | 0% | $238,856 |
| Bank of New York Mellon Corp | 0.2% | 75,267 | 0% | 0% | $222,038 |
| Perigon Wealth Management, LLC | 0.19% | 72,685 | 0% | 0% | $214,421 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.19% | 71,532 | +220% | 0% | $211,019 |
| JANE STREET GROUP, LLC | 0.18% | 68,826 | 0% | $203,037 | |
| Requisite Capital Management, LLC | 0.14% | 55,648 | 0% | 0.03% | $164,162 |
| Ballentine Partners, LLC | 0.13% | 49,664 | 0% | 0% | $146,509 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.12% | 45,705 | 0% | 0% | $134,830 |
| Twelve Points Wealth Management LLC | 0.11% | 43,388 | 0% | 0.04% | $160,102 |
| HighTower Advisors, LLC | 0.11% | 42,234 | 0% | 0% | $124,590 |
Institutional Holders of SERA PROGNOSTICS, INC. - Class A Common Stock, par value $0.0001 per share (SERA) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 5,439,670 | $11,042,321 | +$6,025,655 | $2.03 | 11 |
| 2025 Q4 | 17,640,480 | $52,067,649 | -$1,545,175 | $2.95 | 56 |
| 2025 Q3 | 18,156,273 | $55,563,958 | -$1,352,156 | $3.06 | 61 |
| 2025 Q2 | 18,609,445 | $51,523,609 | -$7,499,389 | $2.77 | 57 |
| 2025 Q1 | 20,231,342 | $74,421,380 | +$7,360,509 | $3.68 | 70 |
| 2024 Q4 | 18,080,486 | $147,052,539 | +$674,056 | $8.14 | 71 |
| 2024 Q3 | 17,992,458 | $140,341,925 | +$11,126,226 | $7.80 | 59 |
| 2024 Q2 | 16,578,359 | $98,177,558 | +$11,498,661 | $5.92 | 65 |
| 2024 Q1 | 14,410,216 | $131,132,861 | +$33,173,495 | $9.10 | 51 |
| 2023 Q4 | 10,917,569 | $65,287,321 | +$31,973,805 | $5.98 | 45 |
| 2023 Q3 | 8,863,155 | $16,485,265 | -$2,039,479 | $1.86 | 27 |
| 2023 Q2 | 9,516,701 | $31,357,944 | -$107,402 | $3.30 | 32 |
| 2023 Q1 | 9,529,218 | $36,496,581 | +$11,033,423 | $3.83 | 35 |
| 2022 Q4 | 7,042,648 | $8,861,320 | -$2,401,722 | $1.26 | 29 |
| 2022 Q3 | 8,696,925 | $13,914,096 | +$64,785 | $1.60 | 31 |
| 2022 Q2 | 8,655,188 | $14,197,000 | -$4,569,945 | $1.64 | 27 |
| 2022 Q1 | 9,651,032 | $36,596,601 | +$1,338,975 | $3.79 | 41 |
| 2021 Q4 | 9,279,441 | $63,795,000 | -$353,446 | $6.87 | 36 |
| 2021 Q3 | 8,651,053 | $96,148,000 | +$96,147,999 | $11.11 | 35 |