Alpine Immune Sciences, Inc.

Ownership Transactions Reported by 21 Insiders

	Insiders	Shares	%	Avg Price	Total $
Buys	2	+750K	17.3%	$12.50	+$9.38M
Sells	5	-3.59M	82.7%	$18.65	-$66.9M
Net	-3	-2.84M	-65.4%		-$57.5M

Name	Relationship	Holdings Value	Past Year Net Change	Change %	Report Date
Decheng Capital China Life Sciences USD Fund III, L.P.	10%+ Owner	$83.9M			Jan 18, 2024
Jay Venkatesan	Director, 10%+ Owner	$36.6M			Jul 15, 2022
Alpine ImmunoSciences, L.P.	10%+ Owner	$33.1M			Sep 17, 2021
Decheng Capital Global Healthcare Fund (Master), LP	10%+ Owner	$22.1M	+$4.69M	+26.9%	Nov 9, 2023
Frazier Life Sciences VIII, L.P.	10%+ Owner	$18.9M			Feb 11, 2022
James Paul Rickey	Senior Vice President, Chief Financial Officer and Corporate Secretary	$0	-$5.6M	-100%	May 20, 2024
Remy Durand	Chief Business Officer	$0			May 20, 2024
James Topper	Director	$0	-$1.23K	-100%	May 18, 2024
Peter A. Thompson	Director	$0	-$28.7M	-100%	May 18, 2024
Orbimed Advisors Llc	Director	$0	-$28.7M	-100%	May 18, 2024
Xiangmin Cui	Director, 10%+ Owner	$0	+$4.69M		May 18, 2024
Stanford L. Peng	President & Head of Research and Development	$0			May 20, 2024
Robert E. Conway	Director	$0			May 20, 2024
Mitchell Gold	Executive Chairman and CEO, Director	$0	-$3.97M	-100%	May 18, 2024
Christopher Peetz	Director	$0			May 20, 2024
Ulrich Martin Fuhs	Chief Accounting Officer	$0			May 20, 2024
Zelanna Goldberg	Chief Medical Officer				Jun 1, 2021
Andrew Seth Sandler	Chief Medical Officer				Jan 5, 2023
Wolfgang Dummer	Chief Medical Officer				Oct 2, 2023
Natasha Hernday	Director				May 20, 2024
Jorn Drappa	Director				May 20, 2024

Insider	Symbol	Class	Transaction	%	Value $	* Price $	Shares	Shares Owned	Date	Ownership

* An asterisk sign (*) next to the price indicates that the price is likely invalid.