SEC ownership of 89bio, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001785173.

Comparable stake leader

VANGUARD GROUP INC

Disclosed value leader

MONTANOVA CAPITAL, LLC

Comparable rows

5/9

Latest evidence

30 Oct 2025

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
5 of 9
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
VANGUARD GROUP INC
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Oct 2025
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001785173
Issuer location
San Francisco, CA

Ownership snapshot

Top shareholders of 89bio, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
VANGUARD GROUP INC
Disclosed value leader
MONTANOVA CAPITAL, LLC
Comparable rows
5/9
Latest evidence
30 Oct 2025
13D/G 3/4/5 Lead comparable stake: 5.6% 4 rows are not safely comparable across share classes. 13D/G row: VANGUARD GROUP INC Showing 1-8 of 9 holder rows.

Quick read

VANGUARD GROUP INC leads the comparable SEC ownership view at 5.6%.

5 of 9 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens VANGUARD GROUP INC's linked filing trail.
Comparable ownership Top 5
VANGUARD GROUP INC 5.6%
MONTANOVA CAPITAL, LLC 5.6%
Janus Henderson Group Ltd. 3.6%
BIOTECHNOLOGY VALUE FUND L P 3.6%
RTW INVESTMENTS, LP 1.3%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 9 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
VANGUARD GROUP INC
13D/G
The Vanguard Group
5.6%
Reported 13D/G · 30 Jun 2025
$80,937,952
8,242,154 shares
$0 30 Jun 2025
MONTANOVA CAPITAL, LLC
13D/G
SUVRETTA CAPITAL MANAGEMENT, LLC
5.6%
Reported 13D/G · 30 Sep 2025
$121,716,000
8,280,000 shares
-$93,071,712 30 Sep 2025
Janus Henderson Group Ltd.
13D/G
JANUS HENDERSON GROUP PLC
3.6%
Reported 13D/G · 30 Sep 2025
$79,060,933
5,378,185 shares
-$226,534,240 30 Sep 2025
BIOTECHNOLOGY VALUE FUND L P
13D/G
BVF PARTNERS L P/IL
3.6%
Reported 13D/G · 31 Dec 2024
$29,903,806
4,333,885 shares
$0 31 Dec 2024
RTW INVESTMENTS, LP
13D/G
1.3%
Reported 13D/G · 31 Mar 2025
$13,575,936
1,967,527 shares
$0 31 Mar 2025
RA CAPITAL MANAGEMENT, L.P.
3/4/5
Director, 10%+ Owner
—
$36,809,857
— 30 Oct 2025
ORBIMED ADVISORS LLC
3/4/5
10%+ Owner
—
denominator unverified
$21,093,397
1,829,436 shares
— 25 Jan 2022
Gregory Grunberg
3/4/5
Director, 10%+ Owner
—
denominator unverified
—
27,400 shares
— 09 Feb 2023
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

No eligible buy or sell activity is available for this window. No eligible Buy or Sell transactions are available in this dataset since 05 Nov 2025.

Buys
$0
Insiders: 0
Sells
$0
Insiders: 0
Net
$0
Shares: 0
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 0
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 0 0 $0 $0 $0
9-12 0 0 $0 $0 $0

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-17 of 17 reporting-owner rows connected to 89bio, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
17
Largest Forms 3/4/5 holder
RA CAPITAL MANAGEMENT, L.P.
Net 12M change
$0
Latest report
30 Oct 2025
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
RA CAPITAL MANAGEMENT, L.P. Director, 10%+ Owner $36,809,857 Mixed 30 Oct 2025
ORBIMED ADVISORS LLC 10%+ Owner $21,093,397 Mixed 25 Jan 2022
Ram Waisbourd Chief Operating Officer and Chief Business Officer $100,888 Mixed 17 Feb 2022
Charles McWherter Director $0 Mixed 30 Oct 2025
Quoc Le-Nguyen Chief Technical Operations Officer $0 Mixed 30 Oct 2025
Michael R. Hayden Director $0 Mixed 30 Oct 2025
Francis Willard Sarena Chief Operating Officer $0 Mixed 30 Oct 2025
Harry H. Mansbach Chief Medical Officer $0 Mixed 30 Oct 2025
Rohan Palekar Chief Executive Officer, Director $0 Mixed 30 Oct 2025
Ryan Martins Chief Financial Officer $0 Mixed 30 Oct 2025
Gregory Grunberg Director, 10%+ Owner Mixed 09 Feb 2023
Derek DiRocco Director Mixed 30 Oct 2025
Lota S. Zoth Director Mixed 30 Oct 2025
Edward Morrow Atkinson III Director Mixed 30 Oct 2025
Kathleen Laporte Director Mixed 30 Oct 2025
Martin Babler Director Mixed 30 Oct 2025
Steven Altschuler Director Mixed 30 Oct 2025

Recent insider transactions for 89bio, Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
No insider transactions were found in the last 12 months for this issuer.
* marks a reported price that did not pass the local price check.
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