| Insiders | Shares | % | Avg Price | Total $ | |
|---|---|---|---|---|---|
| Buys | 1 | +60,000 | 2.7% | $15.84 | +$950,400 |
| Sells | 8 | -2,152,959 | 97% | $36.40 | -$78,369,899 |
| Net | -7 | -2,092,959 | -95% | -$77,419,499 |
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Report Date |
|---|---|---|---|---|---|
| TPG GP A, LLC | 10%+ Owner | $259,798,480 | -$9,049,600 | -3.4% | 22 Jan 2026 |
| Peter A. Thompson | Director | $157,398,695 | -$7,763,508 | -4.7% | 02 Feb 2026 |
| ORBIMED ADVISORS LLC | Director | $157,398,695 | -$7,763,508 | -4.7% | 02 Feb 2026 |
| Bruce Booth | Director | $109,099,824 | -$22,085,832 | -17% | 21 Oct 2025 |
| Michael Cloonan | President & CEO, Director | $20,421,367 | -$6,327,622 | -24% | 02 Jan 2026 |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10%+ Owner | $6,281,803 | -$21,463,466 | -77% | 20 Nov 2025 |
| Elena Ridloff | Cfo | $966,382 | -$1,966,634 | -67% | 02 Jan 2026 |
| Jennifer Fitzpatrick | Chief Legal Officer | $0 | -$999,329 | -100% | 05 Mar 2026 |
| Paul J. Clancy | Director | 12 Jun 2025 | |||
| Harold Edward Fleming | Director | 12 Jun 2025 | |||
| Joshua Resnick | Director | 12 Jun 2025 | |||
| Charlotte McKee | Chief Medical Officer | 02 Jan 2026 | |||
| Atlas Venture Fund XI, L.P. | 10%+ Owner | 10 Feb 2025 | |||
| Joanne L. Viney | Director | 12 Jun 2025 | |||
| Marcella K. Ruddy | Director | 12 Jun 2025 | |||
| Laurie Stelzer | Director | 12 Jun 2025 | |||
| Lucian Iancovici | Director | 06 Feb 2025 | |||
| Caroline Stark Beer | Chief Business Officer | 02 Jan 2026 |
| Insider | Symbol | Class | Transaction | % | Value $ | * Price $ | Shares | Shares Owned | Date | Ownership |
|---|