Insider Transactions Reported by 20 Insiders of Shattuck Labs, Inc.

Symbol: STTK on Nasdaq
Location: Austin, TX

Key facts

STTK - Shattuck Labs, Inc. has 20 insiders with reported activity on this page.
Net insider value flow over the last year: +$10,731,108.
Recent transaction rows are available for direct filing-level review.

Change

Buy value: $10,943,653; sell value: $212,544.
Net share flow: +12,580,222.

Research use

This page gives a plain-language issuer insider context before you inspect transaction-level evidence.
Use the filing links below to verify timestamps, codes, and ownership impacts directly from SEC forms.

Evidence

Filed on Form 4

Issuer insider activity is sourced from SEC Forms 3, 4, and 5.

See Original Filing

Insider trading overview

Last 12 months

Net insider flow leans to buying over the last 12 months. Net value: +$10,731,108.

Buys

$10,943,653

Shares: 12,612,254

Insiders: 2

Sells

$212,544

Shares: 32,032

Insiders: 2

Net

+$10,731,108

Shares: +12,580,222

Insiders: 0

Window (months)	Buy shares	Sell shares	Buy $	Sell $	Net $
0-3	0	32,032	$0	$212,544	-$212,544
3-6	0	0	$0	$0	$0
6-9	0	0	$0	$0	$0
9-12	12,612,254	0	$10,943,653	$0	+$10,943,653

Shattuck Labs, Inc. executives and other stock owners filed with the SEC include:

Name	Relationship	Holdings Value	Past Year Net Change	Change %	Valuation	Report Date
Josiah Hornblower	Director	$33,436,202			Mixed	15 Jul 2021
Taylor Schreiber	Chief Executive Officer, Director	$17,573,009			Median	12 May 2026
Redmile Group, LLC	Director, 10%+ Owner	$6,924,655			Mixed	25 Aug 2025
Andrew R. Neill	Chief Financial Officer	$1,879,173			Median	12 May 2026
Arundathy N. Pandite	Chief Medical Officer	$1,098,707	-$198,300	-15%	Filing P/S	12 May 2026
Erin Ator Thomson	General Counsel	$1,041,379			Mixed	25 Jan 2023
ORBIMED ADVISORS LLC	Director	$911,970	+$5,471,826	+600%	Filing P/S	25 Aug 2025
Dr. Mona Ashiya	Director	$911,970	+$5,471,826	+600%	Filing P/S	28 Aug 2025
Stephen Stout	General Counsel, Corporate Secretary and Chief Ethics and Compliance Officer	$600,343			Median	15 May 2026
Abhinav A. Shukla	Chief Technical Officer	$555,423	-$14,244	-2.5%	Median	21 May 2026
Casi DeYoung	Chief Business Officer	$304,942			Mixed	25 Jan 2026
Clay B. Siegall	Director	$111,112			Mixed	25 Aug 2025
Carrie Brownstein	Director				Mixed	14 Jul 2025
Tyler Brous	Director				Mixed	14 Jul 2025
Amy Kate Sasser	Director				Mixed	14 Jul 2025
George Golumbeski	Director				Mixed	14 Jul 2025
Daniel G. Baker	Director				Mixed	28 Aug 2025
Helen M. Boudreau	Director				Mixed	14 Jul 2025
Michael Stewart Lee	Director				Mixed	14 Jul 2025
Neil W. Gibson	Director				Mixed	14 Jul 2025

Top shareholders of Shattuck Labs, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
T. Rowe Price Investment Management, Inc.	13F 13D/G	Company	14% from 13D/G	9,865,558	$63,436,000	—	31 Mar 2026	13F 13D/G
ORBIMED ADVISORS LLC	13F 13D/G 3/4/5	Company · Director	10% from 13D/G	6,306,127	$40,548,397	—	31 Mar 2026	13F 13D/G 3/4/5
Redmile Group, LLC	13F 13D/G 3/4/5	Company · Director, 10%+ Owner	9.9% from 13D/G	5,539,724	$35,620,425	—	31 Mar 2026	13F 13D/G 3/4/5
Prosight Management, LP	13F 13D/G	Company	9.9% from 13D/G	5,004,439	$32,178,543	—	31 Mar 2026	13F 13D/G
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F 13D/G	Company · Adage Capital Management, L.P.	9.8% from 13D/G	4,644,957	$29,867,074	—	31 Mar 2026	13F 13D/G
VANGUARD GROUP INC	13D/G	The Vanguard Group	4.5%	2,148,174	$1,437,343	$0	30 Jun 2025	13D/G
BlackRock, Inc.	13F 13D/G	Company	1.8% from 13D/G	510,806	$3,284,483	—	31 Mar 2026	13F 13D/G
Arundathy N. Pandite	3/4/5	Chief Medical Officer	0.23%	166,219	$1,098,707	-$198,300	12 May 2026	3/4/5
Casi DeYoung	3/4/5	Chief Business Officer	0.1%	73,480	$304,942	—	25 Jan 2026	3/4/5
NEXTBio Capital Management LP	13F	Company	4.4%	3,149,907	$20,253,902	—	31 Mar 2026	13F
VANGUARD CAPITAL MANAGEMENT LLC	13F	Company	3.2%	2,277,176	$14,642,242	—	31 Mar 2026	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	2.5%	1,782,788	$11,464,000	—	31 Mar 2026	13F
CLARK ESTATES INC/NY	13F	Company	2.1%	1,475,648	$9,488,417	—	31 Mar 2026	13F
PINNACLE ASSOCIATES LTD	13F	Company	1.9%	1,368,223	$8,797,674	—	31 Mar 2026	13F
Aberdeen Group plc	13F	Company	1.6%	1,159,321	$7,454,434	—	31 Mar 2026	13F
Point72 Asset Management, L.P.	13F	Company	1.4%	1,031,049	$6,629,645	—	31 Mar 2026	13F
AMERIPRISE FINANCIAL INC	13F	Company	1.3%	905,707	$5,823,707	—	31 Mar 2026	13F
683 Capital Management, LLC	13F	Company	1.1%	800,000	$5,144,000	—	31 Mar 2026	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	1.1%	763,745	$4,910,880	—	31 Mar 2026	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	1%	715,965	$4,603,655	—	31 Mar 2026	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.9%	645,705	$4,153,899	—	31 Mar 2026	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	0.85%	604,500	$3,886,935	—	31 Mar 2026	13F
MARSHALL WACE, LLP	13F	Company	0.81%	581,471	$3,738,860	—	31 Mar 2026	13F
S&G Foundation	13F	Company	0.61%	435,749	$2,801,866	—	31 Mar 2026	13F
JANE STREET GROUP, LLC	13F	Company	0.58%	415,938	$2,674,482	—	31 Mar 2026	13F
FMR LLC	13F	Company	0.55%	392,500	$2,523,775	—	31 Mar 2026	13F
TD ASSET MANAGEMENT INC	13F	Company	0.54%	382,648	$2,460,427	—	31 Mar 2026	13F
VANGUARD FIDUCIARY TRUST CO	13F	Company	0.45%	324,588	$2,087,101	—	31 Mar 2026	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.44%	316,012	$2,031,957	—	31 Mar 2026	13F
DIADEMA PARTNERS LP	13F	Company	0.41%	293,664	$1,888,260	—	31 Mar 2026	13F
ALGERT GLOBAL LLC	13F	Company	0.4%	286,072	$1,839,000	—	31 Mar 2026	13F
SPHERA FUNDS MANAGEMENT LTD.	13F	Company	0.39%	280,786	$1,805,454	—	31 Mar 2026	13F
STATE STREET CORP	13F	Company	0.37%	263,768	$1,696,028	—	31 Mar 2026	13F
Hudson Bay Capital Management LP	13F	Company	0.32%	228,817	$1,471,294	—	31 Mar 2026	13F
MORGAN STANLEY	13F	Company	0.28%	200,136	$1,286,874	—	31 Mar 2026	13F
DEUTSCHE BANK AG\	13F	Company	0.27%	194,773	$1,252,390	—	31 Mar 2026	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.27%	191,442	$1,230,972	—	31 Mar 2026	13F
ACADIAN ASSET MANAGEMENT LLC	13F	Company	0.26%	183,246	$1,172,000	—	31 Mar 2026	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.22%	155,642	$1,000,778	—	31 Mar 2026	13F
CITADEL ADVISORS LLC	13F	Company	0.21%	148,021	$951,775	—	31 Mar 2026	13F
XTX Topco Ltd	13F	Company	0.2%	142,466	$916,056	—	31 Mar 2026	13F
MANUFACTURERS LIFE INSURANCE COMPANY, THE	13F	Company	0.2%	142,300	$914,989	—	31 Mar 2026	13F
Connor, Clark & Lunn Investment Management Ltd.	13F	Company	0.19%	139,304	$895,725	—	31 Mar 2026	13F
Qube Research & Technologies Ltd	13F	Company	0.18%	126,798	$815,311	—	31 Mar 2026	13F
NORTHERN TRUST CORP	13F	Company	0.18%	126,061	$810,572	—	31 Mar 2026	13F
BARCLAYS PLC	13F	Company	0.17%	119,879	$770,822	—	31 Mar 2026	13F
HRT FINANCIAL LP	13F	Company	0.13%	90,698	$583,000	—	31 Mar 2026	13F
Bank of New York Mellon Corp	13F	Company	0.13%	89,774	$577,246	—	31 Mar 2026	13F
LBJ Family Wealth Advisors, Ltd.	13F	Company	0.11%	82,177	$490,000	—	31 Mar 2026	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.11%	79,924	$513,911	—	31 Mar 2026	13F

Recent Insider Transactions by Companies or Individuals for Shattuck Labs, Inc.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider	Symbol	Class	Transaction	%	Value $	* Price $	Shares	Shares Owned	Date	Ownership
Abhinav A. Shukla	STTK	Common Stock	Award	6.3%			5,122	86,380	21 May 2026	Direct
Abhinav A. Shukla	STTK	Warrants (Right to Buy)	Options Exercise	-100%			-5,122	0	21 May 2026	Direct
Stephen Stout	STTK	Common Stock	Award	15.9%			12,805	93,366	15 May 2026	Direct
Stephen Stout	STTK	Warrants (Right to Buy)	Options Exercise	-100%			-12,805	0	15 May 2026	Direct
Andrew R. Neill	STTK	Common Stock	Award	28%			64,027	292,251	12 May 2026	Direct
Andrew R. Neill	STTK	Warrants (Right to Buy)	Options Exercise	-100%			-64,027	0	12 May 2026	Direct
Abhinav A. Shukla	STTK	Common Stock	Sale	-2.44%	$14,244	$7.01	-2,032	81,258	12 May 2026	Direct
Abhinav A. Shukla	STTK	Common Stock	Options Exercise	2.5%			2,032	83,290	12 May 2026	Direct
Abhinav A. Shukla	STTK	Stock Option (Right to Buy)	Options Exercise	-3.89%			-2,032	50,168	12 May 2026	Direct
Arundathy N. Pandite	STTK	Common Stock	Sale	-15.3%	$198,300	$6.61	-30,000	166,219	12 May 2026	Direct
Taylor Schreiber	STTK	Common Stock	Award	26.5%			25,610	122,222	12 May 2026	Direct
Taylor Schreiber	STTK	Warrants (Right to Buy)	Options Exercise	-100%			-25,610	0	12 May 2026	Direct
Stephen Stout	STTK	Common Stock	Tax liability	-1.19%			-968	80,561	10 May 2026	Direct
Arundathy N. Pandite	STTK	Common Stock	Tax liability	-1.6%			-3,195	196,219	25 Jan 2026	Direct
Stephen Stout	STTK	Common Stock	Tax liability	-0.72%			-593	81,529	25 Jan 2026	Direct
Andrew R. Neill	STTK	Common Stock	Tax liability	-1.12%			-2,589	228,224	25 Jan 2026	Direct
Casi DeYoung	STTK	Common Stock	Tax liability	-3.02%			-2,286	73,480	25 Jan 2026	Direct
Stephen Stout	STTK	Common Stock	Tax liability	-4.81%			-4,153	82,122	10 Jan 2026	Direct
Stephen Stout	STTK	Stock Option (Right to Buy)	Award				351,400	351,400	10 Jan 2026	Direct
Casi DeYoung	STTK	Common Stock	Tax liability	-7%			-5,699	75,766	10 Jan 2026	Direct
Casi DeYoung	STTK	Common Stock	Award				381,600	381,600	10 Jan 2026	Direct
Abhinav A. Shukla	STTK	Common Stock	Award				315,500	315,500	10 Jan 2026	Direct
Arundathy N. Pandite	STTK	Common Stock	Tax liability	-3.32%			-6,851	199,414	10 Jan 2026	Direct
Arundathy N. Pandite	STTK	Common Stock	Award				487,800	487,800	10 Jan 2026	Direct
Andrew R. Neill	STTK	Common Stock	Tax liability	-2.8%			-6,660	230,813	10 Jan 2026	Direct
Andrew R. Neill	STTK	Stock Option (Right to Buy)	Award				549,800	549,800	10 Jan 2026	Direct
Taylor Schreiber	STTK	Stock Option (Right to Buy)	Award				1,548,300	1,548,300	10 Jan 2026	Direct
Dr. Mona Ashiya	STTK	Stock Option (Right to Buy)	Award				66,300	66,300	28 Aug 2025	Direct
Dr. Daniel G. Baker	STTK	Stock Option (Right to Buy)	Award				66,300	66,300	28 Aug 2025	Direct
Orbimed Advisors Llc	STTK	Common Stock	Purchase		$5,471,826	$0.8677	6,306,127	5,255,106	25 Aug 2025	See Footnote
Orbimed Advisors Llc	STTK	Common Warrants (right to buy)	Purchase				18,439,788	15,366,490	25 Aug 2025	See Footnote
Orbimed Advisors Llc	STTK	Pre-Funded Warrants (right to buy)	Purchase				12,133,661	10,111,384	25 Aug 2025	See Footnote
Mona Ashiya	STTK	Common Stock	Purchase		$5,471,826	$0.8677	6,306,127	5,255,106	25 Aug 2025	See Footnote
Mona Ashiya	STTK	Common Warrants (right to buy)	Purchase				18,439,788	15,366,490	25 Aug 2025	See Footnote
Mona Ashiya	STTK	Pre-Funded Warrants (right to buy)	Purchase				12,133,661	10,111,384	25 Aug 2025	See Footnote
Stephen Stout	STTK	Common Stock	Award	17.4%			12,805	86,275	25 Aug 2025	Direct
Stephen Stout	STTK	Warrants (Right to Buy)	Award				12,805	12,805	25 Aug 2025	Direct
Andrew R. Neill	STTK	Common Stock	Award	36.9%			64,027	237,473	25 Aug 2025	Direct
Andrew R. Neill	STTK	Warrants (Right to Buy)	Award				64,027	64,027	25 Aug 2025	Direct
Clay B. Siegall	STTK	Common Stock	Award				128,054	128,054	25 Aug 2025	Direct
Clay B. Siegall	STTK	Warrants (Right to Buy)	Award				128,054	128,054	25 Aug 2025	Direct
Taylor Schreiber	STTK	Common Stock	Award	36.1%			25,610	96,612	25 Aug 2025	Direct
Taylor Schreiber	STTK	Warrants (Right to Buy)	Award				25,610	25,610	25 Aug 2025	Direct
Abhinav A. Shukla	STTK	Common Stock	Award	6.73%			5,122	81,258	25 Aug 2025	Direct
Abhinav A. Shukla	STTK	Warrants (Right to Buy)	Award				5,122	5,122	25 Aug 2025	Direct
Redmile Group, LLC	STTK	Common Warrants to Purchase Common Stock	Award				4,097,730	4,097,730	25 Aug 2025	See Footnotes
Redmile Group, LLC	STTK	Pre-Funded Warrants to Purchase Common Stock	Award	132.2%			4,097,730	7,198,553	25 Aug 2025	See Footnotes
Michael Stewart Lee	STTK	Stock Option (Right to Buy)	Award				33,150	33,150	14 Jul 2025	Direct
Redmile Group, LLC	STTK	Stock Option (Right to Buy)	Award				33,150	33,150	14 Jul 2025	See Footnotes
Clay B. Siegall	STTK	Stock Option (Right to Buy)	Award				33,150	33,150	14 Jul 2025	Direct

* An asterisk sign (*) next to the price indicates that the price is likely invalid.