| Craig A. Collard |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-13,500 |
0 |
01 Jul 2022 |
Direct |
| Craig A. Collard |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-16,000 |
0 |
01 Jul 2022 |
Direct |
| STEPHEN GEORGE DILLY |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-5,000 |
0 |
01 Jul 2022 |
Direct |
| STEPHEN GEORGE DILLY |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-1,037,000 |
0 |
01 Jul 2022 |
Direct |
| Mary Christina Thomson |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-188,900 |
0 |
01 Jul 2022 |
Direct |
| William D. Turner |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-171,300 |
0 |
01 Jul 2022 |
Direct |
| Kevin Norrett |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-195,700 |
0 |
01 Jul 2022 |
Direct |
| Christy J. Oliger |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-18,000 |
0 |
01 Jul 2022 |
Direct |
| Mona Ashiya |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-1,964,770 |
0 |
01 Jul 2022 |
See footnotes |
| Mona Ashiya |
|
Series A Warrants |
Disposed to Issuer |
-100% |
|
|
-1,477,124 |
0 |
01 Jul 2022 |
See footnotes |
| Mona Ashiya |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-14,374 |
0 |
01 Jul 2022 |
Direct |
| Vivo Opportunity, LLC |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-161,712 |
0 |
01 Jul 2022 |
By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. |
| Vivo Opportunity, LLC |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-2,735,853 |
0 |
01 Jul 2022 |
By: Vivo Opportunity Fund Holdings, L.P. |
| Vivo Opportunity, LLC |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-431,947 |
0 |
01 Jul 2022 |
By: Vivo Capital Fund IX, L.P. |
| Vivo Opportunity, LLC |
|
Series A Warrants |
Disposed to Issuer |
-100% |
|
|
-75,749 |
0 |
01 Jul 2022 |
By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. |
| Vivo Opportunity, LLC |
|
Series A Warrants |
Disposed to Issuer |
-100% |
|
|
-1,455,384 |
0 |
01 Jul 2022 |
By: Vivo Opportunity Fund Holdings, L.P. |
| Vivo Opportunity, LLC |
|
Series A Warrants |
Disposed to Issuer |
-100% |
|
|
-324,740 |
0 |
01 Jul 2022 |
By: Vivo Capital Fund IX, L.P. |
| Andrew Sinclair |
|
Common Stock, $0.001 par value |
Disposed to Issuer |
-100% |
|
|
-1,314,127 |
0 |
01 Jul 2022 |
See footnotes |
| Andrew Sinclair |
|
Series A Warrants (Right to Buy) |
Disposed to Issuer |
-100% |
|
|
-871,125 |
0 |
01 Jul 2022 |
See footnotes |
| Andrew Sinclair |
|
Stock Option (Right to Buy) |
Disposed to Issuer |
-100% |
|
|
-14,374 |
0 |
01 Jul 2022 |
Direct |
| Sukhi Jagpal |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-249,536 |
0 |
01 Jul 2022 |
Direct |
| Barbara Klencke |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-10,000 |
0 |
01 Jul 2022 |
Direct |
| Barbara Klencke |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-5,000 |
0 |
01 Jul 2022 |
By spouse |
| Barbara Klencke |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-332,551 |
0 |
01 Jul 2022 |
Direct |
| Jeffrey H. Cooper |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-28,002 |
0 |
01 Jul 2022 |
Direct |
| Robert Pelzer |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-26,327 |
0 |
01 Jul 2022 |
Direct |
| Andrew R. Allen |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-1,650 |
0 |
01 Jul 2022 |
Direct |
| Andrew R. Allen |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-20,655 |
0 |
01 Jul 2022 |
Direct |
| Gaurav Aggarwal |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-2,735,853 |
0 |
01 Jul 2022 |
By: Vivo Opportunity Fund Holdings, L.P. |
| Gaurav Aggarwal |
|
Series A Warrant |
Disposed to Issuer |
-100% |
|
|
-1,455,384 |
0 |
01 Jul 2022 |
By: Vivo Opportunity Fund Holdings, L.P. |
| Gaurav Aggarwal |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-14,374 |
0 |
01 Jul 2022 |
Direct |
| Georgia Erbez |
|
Stock Option (right to buy) |
Disposed to Issuer |
-100% |
|
|
-18,000 |
0 |
01 Jul 2022 |
Direct |
| Orbimed Advisors Llc |
|
Common Stock |
Disposed to Issuer |
-100% |
|
|
-1,964,770 |
0 |
01 Jul 2022 |
See footnotes |
| Orbimed Advisors Llc |
|
Series A Warrants |
Disposed to Issuer |
-100% |
|
|
-1,477,124 |
0 |
01 Jul 2022 |
See footnotes |
| William D. Turner |
|
Stock Option (Right to Buy) |
Award |
|
|
|
12,250 |
12,250 |
17 Jun 2022 |
Direct |
| Barbara Klencke |
|
Stock Option (Right to Buy) |
Award |
|
|
|
12,250 |
12,250 |
17 Jun 2022 |
Direct |
| Sukhi Jagpal |
|
Stock Option (Right to Buy) |
Award |
|
|
|
12,250 |
12,250 |
17 Jun 2022 |
Direct |
| STEPHEN GEORGE DILLY |
|
Stock Option (Right to Buy) |
Award |
|
|
|
65,000 |
65,000 |
17 Jun 2022 |
Direct |
| Mary Christina Thomson |
|
Stock Option (Right to Buy) |
Award |
|
|
|
12,250 |
12,250 |
17 Jun 2022 |
Direct |
| Kevin Norrett |
|
Stock Option (Right to Buy) |
Award |
|
|
|
12,250 |
12,250 |
17 Jun 2022 |
Direct |
| Longitude Capital Partners III, LLC |
|
Common Stock |
Other |
|
|
|
16,030 |
8,015 |
27 Apr 2022 |
See footnote |
| Longitude Capital Partners III, LLC |
|
Common Stock |
Other |
-100% |
|
|
-2,139,771 |
0 |
27 Apr 2022 |
See footnote |
| William D. Turner |
|
Common Stock |
Options Exercise |
|
|
|
6,347 |
6,347 |
06 Apr 2022 |
Direct |
| William D. Turner |
|
Common Stock |
Sale |
-100% |
$236,409 |
$37.25 |
-6,347 |
0 |
06 Apr 2022 |
Direct |
| William D. Turner |
|
Stock Option (Right to Buy) |
Options Exercise |
|
|
|
6,347 |
0 |
06 Apr 2022 |
Direct |
| William D. Turner |
|
Common Stock |
Sale |
-100% |
$3,709 |
$37.09 |
-100 |
0 |
05 Apr 2022 |
Direct |
| William D. Turner |
|
Common Stock |
Options Exercise |
|
|
|
100 |
100 |
05 Apr 2022 |
Direct |
| William D. Turner |
|
Stock Option (Right to Buy) |
Options Exercise |
|
|
|
100 |
0 |
05 Apr 2022 |
Direct |
| Mary Christina Thomson |
|
Common Stock |
Sale |
-100% |
$70,277 |
$35.14 |
-2,000 |
0 |
04 Apr 2022 |
Direct |
| Mary Christina Thomson |
|
Common Stock |
Options Exercise |
|
|
|
2,000 |
2,000 |
04 Apr 2022 |
Direct |