A Central Index Key (CIK) is a unique identifier assigned by the SEC to each filer.

Why are some filings missing?

New filings appear as the SEC updates EDGAR, and older records can vary by availability.

How often is this page updated?

Updates follow new EDGAR submissions and periodic data refreshes.

Filer Snapshot

Siren, L.L.C.

CIK 0002005245. SEC filing timeline plus parsed ownership intelligence from 13F, 13D/G, and Forms 3/4/5 where available.

Entity Type

Individual

Total Filings

Latest Filing

14 May 2026

Industry

n/a

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Start with the summary below, then verify the strongest source-backed page for this filer.

Open 13F if you want portfolio holdings.
Open 13D/G or insider pages only when this CIK has those rows.

Open 13F portfolio

Source: SEC Form 13F

13F-HR filed on 14 May 2026 for CIK 0002005245.

View Source Filing

Business address: 10 Quail Road, Greenwich, CT, 06831
Top holdings (ownership): SRRK, LXRX, and GLYC
Top securities (13F): SRRK, KYMR, ERAS, EWTX, ONC, TNGX, BCAX, RVMD, ARWR, MANE, XENE, OLMA, CRNX, LXRX, COGT, STOK, RCUS, GPCR, IRON, and RYTM
State of incorporation: DE
Fiscal year end: 31 December

Filer intelligence

What SEC filings say about Siren, L.L.C.

A compact read of parsed XML filings. 13F, 13D/G, and Forms 3/4/5 are shown separately because they answer different ownership questions.

Open 13F portfolio Save filer

Quick read

Latest parsed 13F shows $3.61B across 100 reported holdings for Q1 2026.
Largest parsed 13F holding: SRRK at $532.16M.
Forms 3/4/5 show insider context for SRRK worth $101.17M.

SEC source mix

Counts show available parsed rows, not one combined ownership total.

XML parsed

13F portfolio 100 rows

Quarterly institutional portfolio holdings.

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13D/G stakes No rows yet

Beneficial ownership and large-stake disclosures.

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Forms 3/4/5 3 rows

Officer, director, and 10% owner holdings or transactions.

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Top parsed 13F holdings

Visual share of the latest parsed 13F portfolio. Values are reported market value, not a recommendation.

Q1 2026 - 14 May 2026

SRRK

14.8%

Scholar Rock Holding Corp

$532.16M

KYMR

7.4%

Kymera Therapeutics Inc

$265.43M

ERAS

Erasca Inc

$181.93M

EWTX

3.9%

Edgewise Therapeutics Inc

$139.55M

ONC

3.8%

BeOne Medicines AG

$138.09M

Forms 3/4/5 insider context

SRRK

25 Jul 2024 · 10% owner

$101.17M

Issuer page Owner page

LXRX

25 Jul 2024 · 10% owner

$92.76M

Issuer page Owner page

GLYC

25 Jul 2024 · 10% owner

$2.29M

Issuer page Owner page

Latest update

What changed recently for Siren, L.L.C.

New filing available

Latest 13F period: Q1 2026. Open the source-backed page to inspect the fresh filing or facts context.

Update date

14 May 2026

Page type

Filer profile

Latest period

Q1 2026

Institutional portfolio context was refreshed from a 13F filing filed on 14 May 2026.

Open filer profile Browse recent public updates

Filer Overview

Siren, L.L.C. has filed 20 SEC EDGAR filings since 29 Jul 2024. Common forms include 13F-HR, 4, N-PX, 13F-HR/A and more.

Siren, L.L.C. SEC filings Siren, L.L.C. 13F portfolio Siren, L.L.C. owner filings

Latest Filings

Recent SEC filings for Siren, L.L.C. with direct links to document and filing folders.

13F-HR File 028-24464

13F-HR filing

Filing date: 14 May 2026
Reporting date: 31 Mar 2026
SEC evidence: Open document Open filing
Next action: Verify source filing

13F-HR File 028-24464

13F-HR filing

Filing date: 13 Feb 2026
Reporting date: 31 Dec 2025
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 001-38501

4

Filing date: 06 Feb 2026
Reporting date: 11 Dec 2025
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 000-30111

4

Filing date: 04 Feb 2026
Reporting date: 02 Feb 2026
SEC evidence: Open document Open filing
Next action: Verify source filing

13F-HR File 028-24464

13F-HR filing

Filing date: 13 Nov 2025
Reporting date: 30 Sep 2025
SEC evidence: Open document Open filing
Next action: Verify source filing

N-PX File 028-24464

N-PX filing

Filing date: 29 Aug 2025
Reporting date: 30 Jun 2025
SEC evidence: Open document Open filing
Next action: Verify source filing

13F-HR File 028-24464

13F-HR filing

Filing date: 13 Aug 2025
Reporting date: 30 Jun 2025
SEC evidence: Open document Open filing
Next action: Verify source filing

13F-HR/A File 028-24464

13F-HR/A filing

Filing date: 23 May 2025
Reporting date: 31 Mar 2025
SEC evidence: Open document Open filing
Next action: Verify source filing

13F-HR File 028-24464

13F-HR filing

Filing date: 14 May 2025
Reporting date: 31 Mar 2025
SEC evidence: Open document Open filing
Next action: Verify source filing

13F-HR File 028-24464

13F-HR filing

Filing date: 14 Feb 2025
Reporting date: 31 Dec 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 001-38501

4

Filing date: 12 Dec 2024
Reporting date: 10 Dec 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 001-38501

4

Filing date: 27 Nov 2024
Reporting date: 25 Nov 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

13F-HR File 028-24464

13F-HR filing

Filing date: 13 Nov 2024
Reporting date: 30 Sep 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 001-36177

4

Filing date: 09 Aug 2024
Reporting date: 07 Aug 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 001-36177

4

Filing date: 07 Aug 2024
Reporting date: 05 Aug 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 001-36177

4

Filing date: 05 Aug 2024
Reporting date: 01 Aug 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

4 File 001-36177

4

Filing date: 30 Jul 2024
Reporting date: 26 Jul 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

3 File 001-38501

3

Filing date: 29 Jul 2024
Reporting date: 25 Jul 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

3 File 001-36177

3

Filing date: 29 Jul 2024
Reporting date: 25 Jul 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

3 File 000-30111

3

Filing date: 29 Jul 2024
Reporting date: 25 Jul 2024
SEC evidence: Open document Open filing
Next action: Verify source filing

About this filer

Siren, L.L.C. files with the SEC under CIK 0002005245. This page aggregates EDGAR filings and related ownership activity.

FAQ

What is a CIK?: A Central Index Key (CIK) is a unique identifier assigned by the SEC to each filer.
Why are some filings missing?: New filings appear as the SEC updates EDGAR, and older records can vary by availability.
How often is this page updated?: Updates follow new EDGAR submissions and periodic data refreshes.

Siren, L.L.C.

Follow future filing-backed changes

What SEC filings say about Siren, L.L.C.

Quick read

SEC source mix

Top parsed 13F holdings

SRRK

KYMR

ERAS

EWTX

ONC

Forms 3/4/5 insider context

What changed recently for Siren, L.L.C.

Filer Overview

Latest Filings

13F-HR filing

13F-HR filing

4

4

13F-HR filing

N-PX filing

13F-HR filing

13F-HR/A filing

13F-HR filing

13F-HR filing

4

4

13F-HR filing

4

4

4

4

3

3

3

About this filer

FAQ

Related pages for Siren, L.L.C.