Keli Walbert - 11 Dec 2025 Form 4 Insider Report for SPRUCE BIOSCIENCES, INC. (SPRB)

Role
Director
Signature
/s/ Samir Gharib, Attorney-in-Fact
Issuer symbol
SPRB
Transactions as of
11 Dec 2025
Net transactions value
$0
Form type
4
Filing time
15 Dec 2025, 18:46:09 UTC
Previous filing
10 Jan 2025
Next filing
05 Jan 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Walbert Keli Director C/O SPRUCE BIOSCIENCES, INC., 611 GATEWAY BOULEVARD, SUITE 740, SOUTH SAN FRANCISCO /s/ Samir Gharib, Attorney-in-Fact 15 Dec 2025 0002051489

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction SPRB Stock Option (Right to Buy) Award $0 +3,400 $0.000000 3,400 11 Dec 2025 Common Stock 3,400 $88.41 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 The option vests in equal monthly installments over a three year period such that the option is fully vested on the third anniversary of the date of grant, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the "Plan") through each such vesting date and will vest in full upon a Change in Control (as defined in the Plan).