SEC ownership of LeonaBio, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001620463.

Comparable stake leader

Sermonix Pharmaceuticals, Inc.

Disclosed value leader

PERCEPTIVE ADVISORS LLC

Comparable rows

7/50

Latest evidence

28 Oct 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
7 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
Sermonix Pharmaceuticals, Inc.
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
28 Oct 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001620463
Issuer location
Bothell, WA

Ownership snapshot

Top shareholders of LeonaBio, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Sermonix Pharmaceuticals,...
Disclosed value leader
PERCEPTIVE ADVISORS LLC
Comparable rows
7/50
Latest evidence
28 Oct 2026
13D/G 3/4/5 13F Lead comparable stake: 25% 43 rows are not safely comparable across share classes. 13D/G row: Sermonix Pharmaceuticals, Inc. Showing 1-8 of 50 holder rows.

Quick read

Sermonix Pharmaceuticals, Inc. leads the comparable SEC ownership view at 25%.

7 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Sermonix Pharmaceuticals, Inc.'s linked filing trail.
Comparable ownership Top 5
Sermonix Pharmaceuticals, Inc. 25%
PERCEPTIVE ADVISORS LLC 20%
ACORN BIOVENTURES, L.P. 12%
ADAR1 Capital Management, LLC 7.7%
GREAT POINT PARTNERS LLC 5%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Sermonix Pharmaceuticals, Inc.
13D/G
25%
Reported 13D/G · 26 Oct 2026
$11,264,709
3,149,470 shares
-$8,415,732 26 Oct 2026
PERCEPTIVE ADVISORS LLC
3/4/5 13D/G 13F
Director, 10%+ Owner · Company
20%
Reported 13D/G · 26 Oct 2026
$23,327,580
4,638,210 shares
mixed-class rows
— 26 Oct 2026
ACORN BIOVENTURES, L.P.
13D/G
Anders Hove
12%
Reported 13D/G · 18 Aug 2026
$14,208,800
1,492,521 shares
$0 18 Aug 2026
ADAR1 Capital Management, LLC
13F 13D/G
Company
7.7%
Reported 13D/G · 31 Mar 2026
$7,141,549
777,100 shares
— 30 Jun 2026
GREAT POINT PARTNERS LLC
13D/G
5%
Reported 13D/G · 28 Oct 2026
$2,926,709
474,345 shares
$0 28 Oct 2026
Steven Michael Oliveira
13D/G
Oliveira Steven Michael
4.1%
Reported 13D/G · 01 Oct 2025
$69,324
161,218 shares
-$788,375 01 Oct 2025
Baselake Partners, LP
13D/G
1.9%
Reported 13D/G · 31 Dec 2025
$573,723
75,789 shares
-$921,208 31 Dec 2025
David J. Portman
3/4/5
10%+ Owner
—
denominator unverified
$11,264,709
3,149,470 shares
— 26 Oct 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$99,418.

Buys
$0
Insiders: 0
Sells
$99,418
Insiders: 5
Net
-$99,418
Shares: -16,748
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 16,748
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 0 10,469 $0 $56,219 -$56,219
9-12 0 6,279 $0 $43,200 -$43,200

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 23 reporting-owner rows connected to LeonaBio, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
23
Largest Forms 3/4/5 holder
PERCEPTIVE ADVISORS LLC
Net 12M change
-$99.42KFull value: -$99,418 · USD · 12-month change
Latest report
26 Oct 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
PERCEPTIVE ADVISORS LLC Director, 10%+ Owner $23,327,580 Mixed 26 Oct 2026
David J. Portman 10%+ Owner $11,264,709 Median 26 Oct 2026
Joseph Edelman Director, 10%+ Owner $7,702,599 Mixed 26 Oct 2026
PERCEPTIVE LIFE SCIENCES MASTER FUND LTD Director, 10%+ Owner $7,702,599 Mixed 26 Oct 2026
Mark James Litton PRESIDENT and CEO, Director $445,121 -$45,479 -9.3% Mixed 09 Apr 2026
Hans Moebius Chief Medical Officer $266,213 Mixed 04 Jan 2024
Kelly A. Romano Director $194,951 Filing P/S 23 Jun 2026
Kevin Church Chief Scientific Officer $168,112 -$13,325 -7.3% Mixed 09 Apr 2026
Mark Worthington GENERAL COUNSEL and CCO $130,855 -$13,158 -9.1% Mixed 09 Apr 2026
Javier San Martin Chief Medical Officer $126,995 -$20,547 -14% Mixed 09 Apr 2026
Robert Renninger Chief Financial Officer $107,033 -$6,909 -6.1% Mixed 09 Apr 2026
Andrew Gengos CFO and Chief Business Officer $55,203 Filing P/S 03 Sep 2024
Rachel Lenington COO and CDO $11,812 Filing P/S 03 Sep 2024
Tadataka Yamada Director Mixed 28 May 2021
Glenna Mileson Chief Financial Officer Mixed 19 Jan 2023
Peter B. Silverman Director Mixed 23 Jun 2026
Natalie C. Holles Director Mixed 23 Jun 2026
Fred P. Callori Director Mixed 23 Jun 2026
Barbara Kosacz Director Mixed 23 Jun 2026
Grant Pickering Director Mixed 23 Jun 2026

Recent insider transactions for LeonaBio, Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
David J. Portman LONA Common Stock Purchase 3,149,470 3,149,470 26 Oct 2026 See note
David J. Portman LONA Warrant Purchase -100% -5,502,402 0 26 Oct 2026 See note
Perceptive Advisors Llc LONA Common Stock Options Exercise 776,648 776,648 26 Oct 2026 See Footnotes
PERCEPTIVE ADVISORS LLC LONA Common Stock Options Exercise 776,648 776,648 26 Oct 2026 See Footnotes
Perceptive Advisors Llc LONA Common Stock Options Exercise 776,648 776,648 26 Oct 2026 See Footnotes
Perceptive Advisors Llc LONA Pre-Funded Warrant (right to buy) Options Exercise -100% -776,648 0 26 Oct 2026 See Footnotes
PERCEPTIVE ADVISORS LLC LONA Pre-Funded Warrant (right to buy) Options Exercise -100% -776,648 0 26 Oct 2026 See Footnotes
Perceptive Advisors Llc LONA Pre-Funded Warrant (right to buy) Options Exercise -100% -776,648 0 26 Oct 2026 See Footnotes
Perceptive Advisors Llc LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 See footnote
PERCEPTIVE ADVISORS LLC LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 See footnote
Perceptive Advisors Llc LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 See footnote
Fred P. Callori LONA Stock Option (Right to Buy) Award 2,333 2,333 23 Jun 2026 Direct
Natalie C. Holles LONA Stock Option (Right to Buy) Award 2,333 2,333 23 Jun 2026 Direct
Peter B. Silverman LONA Stock Option (Right to Buy) Award 2,333 2,333 23 Jun 2026 Direct
Michael A. Panzara LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 Direct
Kelly A. Romano LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 Direct
Joseph Edelman LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 Direct
James A. Johnson LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 Direct
Barbara Kosacz LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 Direct
Grant Pickering LONA Stock Option (Right to Buy) Award 28,000 28,000 23 Jun 2026 Direct
Natalie C. Holles LONA Stock Option (Right to Buy) Award 56,000 56,000 05 May 2026 Direct
Peter B. Silverman LONA Stock Option (Right to Buy) Award 56,000 56,000 05 May 2026 Direct
Fred P. Callori LONA Stock Option (Right to Buy) Award 56,000 56,000 05 May 2026 Direct
Perceptive Advisors Llc LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 See footnote
PERCEPTIVE ADVISORS LLC LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 See footnote
Perceptive Advisors Llc LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 See footnote
Michael A. Panzara LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 Direct
Kevin Church LONA Stock Option (Right to Buy) Award 300,000 300,000 09 Apr 2026 Direct
Barbara Kosacz LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 Direct
Grant Pickering LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 Direct
Kelly A. Romano LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 Direct
James A. Johnson LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 Direct
Joseph Edelman LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 Direct
Javier San Martin LONA Stock Option (Right to Buy) Award 350,000 350,000 09 Apr 2026 Direct
John M. Fluke Jr. LONA Stock Option (Right to Buy) Award 28,000 28,000 09 Apr 2026 Direct
Mark Worthington LONA Stock Option (Right to Buy) Award 300,000 300,000 09 Apr 2026 Direct
Robert Renninger LONA Stock Option (Right to Buy) Award 300,000 300,000 09 Apr 2026 Direct
Mark James Litton LONA Stock Option (Right to Buy) Award 750,000 750,000 09 Apr 2026 Direct
Mark James Litton LONA Common Stock Sale -8.17% -$27,688 $5.37 -5,156 57,926 04 Mar 2026 Direct
Robert Renninger LONA Common Stock Sale -5.41% -$4,865 $5.37 -906 15,851 04 Mar 2026 Direct
Mark Worthington LONA Common Stock Sale -6.74% -$7,131 $5.37 -1,328 18,376 04 Mar 2026 Direct
Kevin Church LONA Common Stock Sale -5.12% -$7,298 $5.37 -1,359 25,178 04 Mar 2026 Direct
Javier San Martin LONA Common Stock Sale -9.77% -$9,236 $5.37 -1,720 15,887 04 Mar 2026 Direct
Mark James Litton LONA Common Stock Options Exercise 54.5% 22,254 63,082 03 Mar 2026 Direct
Mark James Litton LONA Restricted Stock Units Options Exercise -100% -22,254 0 03 Mar 2026 Direct
Robert Renninger LONA Common Stock Options Exercise 30.3% 3,900 16,757 03 Mar 2026 Direct
Robert Renninger LONA Restricted Stock Units Options Exercise -100% -3,900 0 03 Mar 2026 Direct
Mark Worthington LONA Common Stock Options Exercise 41% 5,726 19,704 03 Mar 2026 Direct
Mark Worthington LONA Restricted Stock Units Options Exercise -100% -5,726 0 03 Mar 2026 Direct
Kevin Church LONA Common Stock Options Exercise 28.3% 5,856 26,537 03 Mar 2026 Direct
* marks a reported price that did not pass the local price check.
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