SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share (SPRB)

Q: What does CUSIP 85209E208 represent in this 13F holders report?

CUSIP 85209E208 is the security identifier for SPRB - SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held SPRB - SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share in Q1 2026?

32 institutional investors reported SPRB - SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share for Q1 2026. Use the holders table for investor-level position and value details.

CUSIP: 85209E208

Q1 2026 13F Holders as of 31 Mar 2026

Security type / class: Equity / Common Stock, par value $0.0001 per share
Total 13F shares: 739,765
Total 13F value: $48,344,484
Share change: -18,520
SEC-reported price per share: $65.35
Number of holders: 32
Value change: -$3,009,590
Number of buys: 13
Number of sells: 14
Shares outstanding: 2,775,534

Security key

85209E208

Report period

Q1 2026

Institutions

Top holders

SPRB full security history Ownership snapshot Full 13F holder table Newer quarter: Q2 2026 Previous quarter: Q4 2025 SPRUCE BIOSCIENCES, INC. SEC filings SPRUCE BIOSCIENCES, INC. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 85209E208

Newer quarter: Q2 2026 Previous quarter: Q4 2025

Recent filing periods:

Q2 2026 Q1 2026 Q4 2025 Q3 2025

Ownership snapshot

Top reported holders of SPRB - SPRUCE BIOSCIENCES, INC. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

Ikarian Capital, LLC

Disclosed value leader

Ikarian Capital, LLC

Comparable rows

15/15

Latest evidence

18 Feb 2026

13F 13D/G 3/4/5 Lead comparable stake: 11% 13D/G row: Ikarian Capital, LLC Showing 1-6 of 15 holder rows.

Quick read

Ikarian Capital, LLC leads the comparable SEC ownership view at 11%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Ikarian Capital, LLC's linked filing trail.

Comparable ownership Top 5

Ikarian Capital, LLC 11%

Boone Peter David Mr 6.4%

ADAR1 Capital Management, LLC 5.4%

CITADEL ADVISORS LLC 5.1%

Carlyle Group Inc. 4.7%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
Ikarian Capital, LLC	13F 13D/G Company 13F 13D/G	11% from 13D/G	$10,571,320 121,356 shares	—	31 Dec 2025
Boone Peter David Mr	13D/G 13D/G	6.4%	$8,045,712 68,184 shares	$0	21 Nov 2025
ADAR1 Capital Management, LLC	13F 13D/G Company 13F 13D/G	5.4% from 13D/G	$5,052,380 58,000 shares	—	31 Dec 2025
CITADEL ADVISORS LLC	13F 13D/G Company · Kenneth Griffin 13F 13D/G	5.1% from 13D/G	$6,097,613 69,999 shares	—	31 Dec 2025
Carlyle Group Inc.	13D/G 13F The Carlyle Group Inc. · Company 13D/G 13F	4.7%	$4,208,342 50,893 shares	$0	18 Feb 2026
Alyeska Investment Group, L.P.	13F 13D/G Company 13F 13D/G	4.5% from 13D/G	$4,501,061 51,671 shares	—	31 Dec 2025

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q1 2026

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

739,765

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q1 2026 vs Q4 2025 Across Filers

Q4 2025 holders

Q1 2026 holders

Holder diff

Investor	Q4 2025 Shares	Q1 2026 Shares	Share Diff	Share Chg %	Q4 2025 value	Q1 2026 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend