Security key
85209E208
SPRUCE BIOSCIENCES, INC. - Common Stock (SPRB)
CUSIP: 85209E208
Q3 2025 13F Holders as of 30 Sep 2025
- Security type / class
- Equity / Common Stock
- Total 13F shares
- 2,937,895
- Total 13F value
- $25,135,295
- Share change
- +2,937,895
- SEC-reported price per share
- $8.95
- Number of holders
- 9
- Value change
- +$25,135,295
- Number of buys
- 9
- Shares outstanding
- 2,762,294
Holder snapshot
5 signals
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q3 2025
Institutions
9
Top holders
9
SPRB full security history
Ownership snapshot
Full 13F holder table
Newer quarter: Q4 2025
SPRUCE BIOSCIENCES, INC. SEC filings
SPRUCE BIOSCIENCES, INC. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 85209E208
Recent filing periods:
Ownership snapshot
Top reported holders of SPRB - SPRUCE BIOSCIENCES, INC. - Common Stock (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
RiverVest Venture Fund II...
Disclosed value leader
Novo Holdings A/S
Comparable rows
4/12
Latest evidence
22 Jul 2025
13D/G
13F
3/4/5
Lead comparable stake: 4.2%
8 rows are not safely comparable across share classes.
13D/G row: RiverVest Venture Fund III, L.P.
Showing 1-6 of 12 holder rows.
Quick read
RiverVest Venture Fund III, L.P. leads the comparable SEC ownership view at 4.2%.
4 of 12 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens RiverVest Venture Fund III, L.P.'s linked filing trail.
Comparable ownership
Top 4
RiverVest Venture Fund III, L.P.
4.2%
ACADIAN ASSET MANAGEMENT LLC
76%
Ikarian Capital, LLC
73%
CALDWELL SUTTER CAPITAL, INC.
0.07%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-6 of 12 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| RiverVest Venture Fund III, L.P. |
13D/G
John P. McKearn, Ph.D.
|
4.2%
|
$140,762
1,759,521 shares
|
$0 | 07 Jan 2025 |
| ACADIAN ASSET MANAGEMENT LLC |
13F
Company
|
76%
|
$74,000
1,045,828 shares
|
— | 30 Jun 2025 |
| Ikarian Capital, LLC |
13F
Company
|
73%
|
$72,501
1,000,000 shares
|
— | 30 Jun 2025 |
| CALDWELL SUTTER CAPITAL, INC. |
13F
Company
|
0.07%
|
$73
1,000 shares
|
— | 30 Jun 2025 |
| Novo Holdings A/S |
3/4/5
10%+ Owner
|
—
class O/S missing
|
$1,924,485
2,550,000 shares
|
— | 21 Mar 2024 |
| Ralph William Charlton III |
3/4/5
CHIEF MEDICAL OFFICER
|
—
mixed-class rows
|
$87,394
224,839 shares
mixed-class rows
|
— | 10 Dec 2024 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q3 2025
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
9
Shares
2,937,895
Rows available
9
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q3 2025 vs Q1 2026 Across Filers
Q1 2026 holders
32
Q3 2025 holders
9
Holder diff
-23
| Investor | Q1 2026 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q1 2026 value | Q3 2025 value | Value change | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend