Security key
462222100
IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS)
CUSIP: 462222100
Q1 2026 13F Holders as of 31 Mar 2026
- Type / Class
- Equity / COMMON STOCK
- Shares outstanding
- 166,460,189
- Total 13F shares
- 172,477,503
- Share change
- +2,299,840
- Total reported value
- $12,950,911,014
- Put/Call ratio
- 102%
- Price per share
- $75.09
- Number of holders
- 487
- Value change
- +$153,032,506
- Number of buys
- 237
- Number of sells
- 219
Report period
Q1 2026
Institutions
487
Top holders
10
IONS full security history
Previous quarter: Q4 2025
IONIS PHARMACEUTICALS INC SEC filings
IONIS PHARMACEUTICALS INC company facts
Broader feeds
Reporting periods
Holder history for CUSIP 462222100
Recent filing periods:
Top shareholders of IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Capital World Investors |
13D/G
13F
|
Company |
13%
|
21,186,369
|
$1,592,579,358 | +$242,428,512 | 31 Mar 2026 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
5.7%
from 13D/G
|
10,647,863
|
$842,352,443 | — | 31 Dec 2025 | |
| VANGUARD CAPITAL MANAGEMENT LLC |
13D/G
|
Vanguard Capital Management |
5%
|
8,344,732
|
$626,605,926 | $0 | 31 Mar 2026 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
13D/G
|
Company |
4.3%
from 13D/G
|
6,260,325
|
$495,254,312 | — | 31 Dec 2025 | |
| T. Rowe Price Investment Management, Inc. |
13F
13D/G
|
Company |
3.7%
from 13D/G
|
9,108,019
|
$720,536,000 | — | 31 Dec 2025 | |
| FMR LLC |
13F
|
Company |
14%
|
24,072,101
|
$1,904,343,910 | — | 31 Dec 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
9.9%
|
16,440,459
|
$1,300,604,712 | — | 31 Dec 2025 | |
| Bellevue Group AG |
13F
|
Company |
2.9%
|
4,802,199
|
$379,901,963 | — | 31 Dec 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.4%
|
3,974,865
|
$314,451,570 | — | 31 Dec 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.9%
|
3,148,849
|
$249,157,703 | — | 31 Dec 2025 | |
| TWO SIGMA ADVISERS, LP |
13F
|
Company |
1.8%
|
3,052,111
|
$241,452,501 | — | 31 Dec 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
1.8%
|
2,987,840
|
$236,370,000 | — | 31 Dec 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
1.6%
|
2,658,646
|
$210,325,485 | — | 31 Dec 2025 | |
| Tweedy, Browne Co LLC |
13F
|
Company |
1.5%
|
2,464,930
|
$195,000,612 | — | 31 Dec 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
1.4%
|
2,304,792
|
$182,332,112 | — | 31 Dec 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
1.3%
|
2,134,636
|
$168,871,054 | — | 31 Dec 2025 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. |
13F
|
Company |
1.2%
|
1,979,669
|
$156,611,615 | — | 31 Dec 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
1.1%
|
1,791,841
|
$141,752,542 | — | 31 Dec 2025 | |
| Deep Track Capital, LP |
13F
|
Company |
1%
|
1,700,000
|
$134,487,000 | — | 31 Dec 2025 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
0.97%
|
1,617,106
|
$127,929,439 | — | 31 Dec 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.93%
|
1,541,841
|
$121,975,042 | — | 31 Dec 2025 | |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC |
13F
|
Company |
0.88%
|
1,462,706
|
$115,714,672 | — | 31 Dec 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.85%
|
1,418,491
|
$112,476,314 | — | 31 Dec 2025 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.83%
|
1,388,567
|
$109,849,535 | — | 31 Dec 2025 | |
| BNP Paribas Asset Management Holding S.A. |
13F
|
Company |
0.81%
|
1,352,837
|
$107,029,000 | — | 31 Dec 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
0.8%
|
1,333,424
|
$105,487,173 | — | 31 Dec 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.79%
|
1,321,345
|
$104,531,581 | — | 31 Dec 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.76%
|
1,269,290
|
$100,413,532 | — | 31 Dec 2025 | |
| Artisan Partners Limited Partnership |
13F
|
Company |
0.71%
|
1,181,416
|
$93,461,820 | — | 31 Dec 2025 | |
| ROYAL BANK OF CANADA |
13F
|
Company |
0.67%
|
1,118,797
|
$88,509,000 | — | 31 Dec 2025 | |
| Connor, Clark & Lunn Investment Management Ltd. |
13F
|
Company |
0.65%
|
1,076,370
|
$85,151,631 | — | 31 Dec 2025 | |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
13F
|
Company |
0.64%
|
1,063,327
|
$84,119,799 | — | 31 Dec 2025 | |
| UBS Group AG |
13F
|
Company |
0.63%
|
1,045,041
|
$82,673,193 | — | 31 Dec 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.61%
|
1,019,906
|
$80,684,891 | — | 31 Dec 2025 | |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
13F
|
Company |
0.52%
|
864,892
|
$68,422,000 | — | 31 Dec 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.51%
|
855,966
|
$67,715,470 | — | 31 Dec 2025 | |
| NOMURA HOLDINGS INC |
13F
|
Company |
0.51%
|
848,815
|
$67,149,755 | — | 31 Dec 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.51%
|
846,718
|
$66,983,861 | — | 31 Dec 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.51%
|
842,871
|
$66,679,526 | — | 31 Dec 2025 | |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
13F
|
Company |
0.49%
|
812,747
|
$64,296,415 | — | 31 Dec 2025 | |
| GW&K Investment Management, LLC |
13F
|
Company |
0.47%
|
786,668
|
$62,234,000 | — | 31 Dec 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.47%
|
783,579
|
$61,988,936 | — | 31 Dec 2025 | |
| TD ASSET MANAGEMENT INC |
13F
|
Company |
0.46%
|
773,184
|
$61,166,586 | — | 31 Dec 2025 | |
| Asset Managment Groupama |
13F
|
Individual |
0.46%
|
766,889
|
$60,668,589 | — | 31 Dec 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.41%
|
677,629
|
$53,609,512 | — | 31 Dec 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.4%
|
660,769
|
$52,273,435 | — | 31 Dec 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.36%
|
598,748
|
$47,366,953 | — | 31 Dec 2025 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.35%
|
584,970
|
$46,276,977 | — | 31 Dec 2025 | |
| EVENTIDE ASSET MANAGEMENT, LLC |
13F
|
Company |
0.35%
|
575,000
|
$45,488,250 | — | 31 Dec 2025 | |
| Tri Locum Partners LP |
13F
|
Company |
0.33%
|
557,174
|
$44,078,035 | — | 31 Dec 2025 |
Institutional Holders of IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) as of Q1 2026
As of 31 Mar 2026,
IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) was held by
487 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
172,477,503 shares.
The largest 10 holders included
FMR LLC, Capital World Investors, BlackRock, Inc., VANGUARD PORTFOLIO MANAGEMENT LLC, VANGUARD CAPITAL MANAGEMENT LLC, WELLINGTON MANAGEMENT GROUP LLP, T. Rowe Price Investment Management, Inc., TWO SIGMA INVESTMENTS, LP, STATE STREET CORP, and GEODE CAPITAL MANAGEMENT, LLC.
This page lists
487
institutional shareholders reporting positions in this security
for the Q1 2026 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q1 2026 vs Q4 2025 Across Filers
Q4 2025 holders
490
Q1 2026 holders
487
Holder diff
-3
| Investor | Q4 2025 Shares | Q1 2026 Shares | Share Diff | Share Chg % | Q4 2025 Value $ | Q1 2026 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.