Security key
462222100
IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS)
CUSIP: 462222100
Q1 2026 13F Holders as of 31 Mar 2026
- Security type / class
- Equity / COMMON STOCK
- Total 13F shares
- 172,535,502
- Total 13F value
- $12,955,266,160
- Share change
- +2,352,688
- Put/Call ratio
- 102%
- SEC-reported price per share
- $75.09
- Number of holders
- 491
- Value change
- +$157,000,862
- Number of buys
- 238
- Number of sells
- 220
- Shares outstanding
- 166,460,189
Holder snapshot
7 signals
Open additional details 1 more signal available
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q1 2026
Institutions
491
Top holders
10
IONS full security history
Ownership snapshot
Full 13F holder table
IONIS PHARMACEUTICALS INC SEC filings
IONIS PHARMACEUTICALS INC company facts
Broader feeds
Ownership snapshot
Top reported holders of IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
Capital World Investors
Disclosed value leader
FMR LLC
Comparable rows
15/15
Latest evidence
31 Mar 2026
13D/G
13F
Lead comparable stake: 13%
13D/G row: Capital World Investors
Showing 1-6 of 15 holder rows.
Quick read
Capital World Investors leads the comparable SEC ownership view at 13%.
15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens Capital World Investors's linked filing trail.
Comparable ownership
Top 5
Capital World Investors
13%
BlackRock, Inc.
5.7%
VANGUARD CAPITAL MANAGEMENT LLC
5%
WELLINGTON MANAGEMENT GROUP LLP
4.3%
T. Rowe Price Investment Manageme...
3.7%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-6 of 15 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Capital World Investors |
13D/G
13F
Company
|
13%
|
$1,592,579,358
21,186,369 shares
|
+$242,428,512 | 31 Mar 2026 |
| BlackRock, Inc. |
13F
13D/G
Company
|
5.7%
from 13D/G
|
$842,352,443
10,647,863 shares
|
— | 31 Dec 2025 |
| VANGUARD CAPITAL MANAGEMENT LLC |
13D/G
Vanguard Capital Management
|
5%
|
$626,605,926
8,344,732 shares
|
$0 | 31 Mar 2026 |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
13D/G
Company
|
4.3%
from 13D/G
|
$495,254,312
6,260,325 shares
|
— | 31 Dec 2025 |
| T. Rowe Price Investment Management, Inc. |
13F
13D/G
Company
|
3.7%
from 13D/G
|
$720,536,000
9,108,019 shares
|
— | 31 Dec 2025 |
| FMR LLC |
13F
Company
|
14%
|
$1,904,343,910
24,072,101 shares
|
— | 31 Dec 2025 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q1 2026
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
491
Shares
172,535,502
Rows available
491
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q1 2026 vs Q1 2026 Across Filers
Q1 2026 holders
491
Q1 2026 holders
491
Holder diff
0
| Investor | Q1 2026 Shares | Q1 2026 Shares | Share Diff | Share Chg % | Q1 2026 value | Q1 2026 value | Value change | Value Chg % |
|---|