IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS)

CUSIP: 462222100

Q1 2025 13F Holders as of 31 Mar 2025

Type / Class
Equity / COMMON STOCK
Shares outstanding
166,460,189
Total 13F shares
165,860,888
Share change
+5,291,035
Total reported value
$5,004,903,523
Put/Call ratio
77%
Price per share
$30.17
Number of holders
340
Value change
+$131,542,151
Number of buys
151
Number of sells
182

Security key

462222100

Report period

Q1 2025

Institutions

340

Top holders

10

Top shareholders of IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
BlackRock, Inc.
13F 13D/G
Company
5.7%
from 13D/G
11,665,548
$407,827,557 31 Dec 2024
FMR LLC
13F
Company
14%
22,689,491
$793,224,593 31 Dec 2024
13F
VANGUARD GROUP INC
13F
Company
9.9%
16,472,539
$575,879,963 31 Dec 2024
13F
T. Rowe Price Investment Management, Inc.
13F
Company
8.5%
14,169,199
$495,356,000 31 Dec 2024
13F
Capital World Investors
13F
Company
6.9%
11,465,413
$400,830,838 31 Dec 2024
13F
WELLINGTON MANAGEMENT GROUP LLP
13F
Company
5.2%
8,672,148
$303,178,294 31 Dec 2024
13F
Bellevue Group AG
13F
Company
4.7%
7,868,700
$275,089,752 31 Dec 2024
13F
STATE STREET CORP
13F
Company
3.3%
5,426,413
$189,707,398 31 Dec 2024
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
2.3%
3,826,939
$133,791,000 31 Dec 2024
13F
Tweedy, Browne Co LLC
13F
Company
2%
3,248,863
$113,580,250 31 Dec 2024
13F
ORBIMED ADVISORS LLC
13F
Company
1.7%
2,817,347
$98,494,451 31 Dec 2024
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.6%
2,687,248
$93,975,889 31 Dec 2024
13F
CITADEL ADVISORS LLC
13F
Company
1.3%
2,165,916
$75,720,424 31 Dec 2024
13F
Deep Track Capital, LP
13F
Company
1.2%
1,933,928
$67,610,123 31 Dec 2024
13F
UBS Group AG
13F
Company
1.2%
1,917,608
$67,039,575 31 Dec 2024
13F
MACQUARIE GROUP LTD
13F
Company
1.1%
1,769,743
$61,870,000 31 Dec 2024
13F
NORGES BANK
13F
Company
1%
1,714,762
$59,948,080 31 Dec 2024
13F
Clearbridge Investments, LLC
13F
Company
0.97%
1,618,220
$56,572,971 31 Dec 2024
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.89%
1,481,440
$51,791,142 31 Dec 2024
13F
TWO SIGMA ADVISERS, LP
13F
Company
0.81%
1,349,211
$47,168,417 31 Dec 2024
13F
MORGAN STANLEY
13F
Company
0.8%
1,329,929
$46,494,395 31 Dec 2024
13F
BNP Paribas Asset Management Holding S.A.
13F
Company
0.65%
1,080,341
$37,768,000 31 Dec 2024
13F
TD ASSET MANAGEMENT INC
13F
Company
0.63%
1,049,990
$36,707,650 31 Dec 2024
13F
ARK Investment Management LLC
13F
Company
0.62%
1,025,260
$35,843,086 31 Dec 2024
13F
TWO SIGMA INVESTMENTS, LP
13F
Company
0.55%
921,439
$32,213,507 31 Dec 2024
13F
S.c.a. Candriam
13F
Individual
0.51%
849,824
$29,709,847 31 Dec 2024
13F
NORTHERN TRUST CORP
13F
Company
0.5%
840,271
$29,375,874 31 Dec 2024
13F
Hudson Bay Capital Management LP
13F
Company
0.49%
821,200
$28,709,152 31 Dec 2024
13F
MARSHALL WACE, LLP
13F
Company
0.49%
812,306
$28,398,216 31 Dec 2024
13F
Invesco Ltd.
13F
Company
0.47%
788,599
$27,569,422 31 Dec 2024
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.47%
774,215
$27,066,556 31 Dec 2024
13F
ROYAL BANK OF CANADA
13F
Company
0.39%
643,192
$22,485,000 31 Dec 2024
13F
Camber Capital Management LP
13F
Company
0.38%
625,000
$21,850,000 31 Dec 2024
13F
Pictet Asset Management Holding SA
13F
Company
0.37%
620,798
$21,703,098 31 Dec 2024
13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC
13F
Company
0.37%
619,641
$21,662,650 31 Dec 2024
13F
Bank of New York Mellon Corp
13F
Company
0.37%
616,071
$21,537,852 31 Dec 2024
13F
J. Goldman & Co LP
13F
Company
0.36%
607,499
$21,238,165 31 Dec 2024
13F
AXA S.A.
13F
Company
0.36%
605,345
$21,162,861 31 Dec 2024
13F
BARCLAYS PLC
13F
Company
0.36%
596,072
$20,838,677 31 Dec 2024
13F
Vestal Point Capital, LP
13F
Company
0.36%
595,000
$20,801,200 31 Dec 2024
13F
PINNACLE ASSOCIATES LTD
13F
Company
0.33%
547,642
$19,145,564 31 Dec 2024
13F
Asset Managment Groupama
13F
Individual
0.31%
517,191
$18,060,310 31 Dec 2024
13F
GREAT POINT PARTNERS LLC
13F
Company
0.3%
505,007
$17,655,045 31 Dec 2024
13F
BANK OF AMERICA CORP /DE/
13F
Company
0.25%
422,861
$14,783,220 31 Dec 2024
13F
JPMORGAN CHASE & CO
13F
Company
0.25%
415,919
$14,540,529 31 Dec 2024
13F
Aberdeen Group plc
13F
Company
0.24%
401,501
$14,028,445 31 Dec 2024
13F
C WorldWide Group Holding A/S
13F
Company
0.24%
400,000
$13,984,000 31 Dec 2024
13F
AMERIPRISE FINANCIAL INC
13F
Company
0.23%
387,448
$13,542,735 31 Dec 2024
13F
GOLDMAN SACHS GROUP INC
13F
Company
0.23%
378,208
$13,222,152 31 Dec 2024
13F
Schonfeld Strategic Advisors LLC
13F
Company
0.22%
371,381
$12,983,479 31 Dec 2024
13F

Institutional Holders of IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) as of Q1 2025

As of 31 Mar 2025, IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) was held by 340 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 165,860,888 shares. The largest 10 holders included FMR LLC, VANGUARD GROUP INC, T. Rowe Price Investment Management, Inc., Capital World Investors, BlackRock, Inc., WELLINGTON MANAGEMENT GROUP LLP, Bellevue Group AG, STATE STREET CORP, Deep Track Capital, LP, and CITADEL ADVISORS LLC. This page lists 342 institutional shareholders reporting positions in this security for the Q1 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q1 2025 vs Q4 2024 Across Filers

Q4 2024 holders
348
Q1 2025 holders
340
Holder diff
-8
Investor Q4 2024 Shares Q1 2025 Shares Share Diff Share Chg % Q4 2024 Value $ Q1 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. Here you can make detailed settings or revoke your consent (in part if necessary) with effect for the future. For further information, please refer to our Privacy Policy .