IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS)

Q4 2025 13F Holders as of 31 Dec 2025

Type / Class
Equity / COMMON STOCK
Shares outstanding
162,643,196
Total 13F shares
170,188,019
Share change
+1,491,798
Total reported value
$13,460,850,503
Put/Call ratio
67%
Price per share
$79.11
Number of holders
486
Value change
+$165,888,207
Number of buys
259
Number of sells
182

Institutional Holders of IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) as of Q4 2025

As of 31 Dec 2025, IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) was held by 486 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 170,188,019 shares. The largest 10 holders included FMR LLC, Capital World Investors, VANGUARD GROUP INC, BlackRock, Inc., T. Rowe Price Investment Management, Inc., WELLINGTON MANAGEMENT GROUP LLP, Bellevue Group AG, STATE STREET CORP, GEODE CAPITAL MANAGEMENT, LLC, and TWO SIGMA ADVISERS, LP. This page lists 486 institutional shareholders reporting positions in this security for the Q4 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.