Insider Transactions Reported by 24 Insiders of IONIS PHARMACEUTICALS INC

Symbol
IONS on Nasdaq
Location
Carlsbad, CA

Insiders trading volume in the past year

IONIS PHARMACEUTICALS INC executives and other stock owners filed with the SEC include:

Name Relationship Holdings Value Past Year Net Change Change % Report Date
Brett P. Monia Chief Executive Officer, Director $47,471,688 -$35,625,406 -43% 09 Mar 2026
HOUGEN ELIZABETH L EVP, Finance & CFO $16,690,976 -$4,803,429 -22% 29 Jan 2026
Eugene Schneider EVP, Chf Clinical Develop Ofcr $9,965,367 -$2,822,890 -22% 29 Jan 2026
C. Frank Bennett EVP, Chief Scientific Officer $9,840,153 -$11,003,052 -53% 03 Mar 2026
Patrick R. O'Neil EVP CLO & General Counsel $8,777,916 -$15,788,467 -64% 09 Mar 2026
Richard S. Geary EVP, Chief Development Officer $8,613,598 -$14,287,270 -62% 05 Nov 2025
Onaiza Cadoret-Manier EVP,Chf GL Pdt Str & Oper Ofc $7,945,126 02 Feb 2024
Joseph T. Baroldi EVP, Chief Business Officer $7,371,330 -$5,529,676 -43% 03 Mar 2026
Brian Birchler EVP, Corp and Development Ops $6,745,075 -$3,502,639 -34% 27 Feb 2026
Spencer R. Berthelsen Director $6,331,181 15 Jul 2025
Eric Swayze EVP Research $5,730,563 -$7,219,293 -56% 27 Feb 2026
B. Lynne Parshall Director $4,660,646 -$2,000,254 -30% 11 Feb 2026
Shannon L. Devers EVP, Chief Human Resources Ofc $4,609,036 -$8,395,933 -65% 03 Mar 2026
Joseph H. Wender Director $4,044,699 -$8,660,121 -68% 01 Dec 2025
Frederick T. Muto Director $3,438,793 15 Jul 2022
Joan E. Herman Director $3,324,298 -$3,173,830 -49% 19 Nov 2025
Kyle Jenne EVP, Chf GL Pdt Str Ofcr $3,180,301 -$3,051,334 -49% 10 Mar 2026
Joseph Loscalzo Director $2,906,400 -$2,246,873 -44% 03 Mar 2026
Michael R. Hayden Director $2,224,333 +$477,900 +27% 15 Jul 2025
Peter N. Reikes Director $1,254,678 15 Oct 2021
Holly B. Kordasiewicz EVP, Chief Development Officer $1,113,563 -$313,308 -22% 15 Jan 2026
Joseph Klein III Director $898,558 -$6,016,181 -87% 03 Mar 2026
Michael J. Yang Director $887,738 15 Jan 2026
Allene M. Diaz Director $307,924 -$4,415,115 -93% 03 Mar 2026

Recent Insider Transactions by Companies or Individuals for IONIS PHARMACEUTICALS INC

Showing up to 300 most recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % Value $ * Price $ Shares Shares Owned Date Ownership
Brett P. Monia IONS Common Stock Sale -12.3% $2,589,144 $75.92 -34,103 242,662 10 Mar 2026 Direct
Brett P. Monia IONS Common Stock Options Exercise 14% 34,103 276,765 10 Mar 2026 Direct
Brett P. Monia IONS Non-Qualified Stock Option (right to buy) Options Exercise -100% -34,103 0 10 Mar 2026 Direct
Kyle Jenne IONS Common Stock Sale -76.1% $2,827,325 $75.85 -37,277 11,714 10 Mar 2026 Direct
Kyle Jenne IONS Common Stock Options Exercise 318.2% 37,277 48,991 10 Mar 2026 Direct
Kyle Jenne IONS Non-Qualified Stock Option (right to buy) Options Exercise -72.7% -37,277 14,025 10 Mar 2026 Direct
Patrick R. O'Neil IONS Common Stock Sale -14% $763,662 $75.25 -10,148 62,211 09 Mar 2026 Direct
Brett P. Monia IONS Common Stock Sale -34.3% $9,525,011 $75.20 -126,670 242,662 09 Mar 2026 Direct
Brett P. Monia IONS Common Stock Options Exercise 44.8% 114,351 369,332 09 Mar 2026 Direct
Brett P. Monia IONS Non-Qualified Stock Option (right to buy) Options Exercise -77% -114,351 34,103 09 Mar 2026 Direct
Joseph Loscalzo IONS Common Stock Sale -0.55% $16,000 $80.00 -200 36,330 04 Mar 2026 Direct
Joseph Loscalzo IONS Common Stock Options Exercise 0.55% 200 36,530 04 Mar 2026 Direct
Joseph Loscalzo IONS Non-Qualified Stock Option (right to buy) Options Exercise -1.79% -200 10,968 04 Mar 2026 Direct
Joseph T. Baroldi IONS Common Stock Sale -9.17% $35,120 $80.00 -439 4,347 04 Mar 2026 by Spouse
Joseph T. Baroldi IONS Common Stock Options Exercise 10.6% 439 4,585 04 Mar 2026 by Spouse
Joseph T. Baroldi IONS Non-Qualified Stock Option (right to buy) Options Exercise -19.9% -439 1,769 04 Mar 2026 by Spouse
Joseph Loscalzo IONS Common Stock Sale -2.24% $66,833 $80.33 -832 36,330 03 Mar 2026 Direct
Joseph Loscalzo IONS Common Stock Options Exercise 2.29% 832 37,162 03 Mar 2026 Direct
Joseph Loscalzo IONS Non-Qualified Stock Option (right to buy) Options Exercise -6.93% -832 11,168 03 Mar 2026 Direct
Joseph Klein III IONS Common Stock Sale -66% $1,696,181 $79.51 -21,332 11,014 03 Mar 2026 Direct
Joseph Klein III IONS Common Stock Options Exercise 97.9% 16,000 32,346 03 Mar 2026 Direct
Joseph Klein III IONS Non-Qualified Stock Option (right to buy) Options Exercise -100% -16,000 0 03 Mar 2026 Direct
Allene M. Diaz IONS Common Stock Sale -93.5% $4,354,428 $79.35 -54,878 3,811 03 Mar 2026 Direct
Allene M. Diaz IONS Common Stock Options Exercise 219.5% 40,321 58,689 03 Mar 2026 Direct
Allene M. Diaz IONS Non-Qualified Stock Option (right to buy) Options Exercise -100% -40,321 0 03 Mar 2026 Direct
Shannon L. Devers IONS Common Stock Sale -47.2% $1,596,433 $79.40 -20,106 22,541 03 Mar 2026 Direct
Shannon L. Devers IONS Common Stock Options Exercise 89.2% 20,106 42,647 03 Mar 2026 Direct
Shannon L. Devers IONS Non-Qualified Stock Option (right to buy) Options Exercise -95.6% -20,106 928 03 Mar 2026 Direct
C. Frank Bennett IONS Common Stock Sale -51.4% $6,741,669 $79.23 -85,089 80,554 03 Mar 2026 Direct
C. Frank Bennett IONS Common Stock Options Exercise 64.7% 65,089 165,643 03 Mar 2026 Direct
C. Frank Bennett IONS Non-Qualified Stock Option (right to buy) Options Exercise -100% -65,089 0 03 Mar 2026 Direct
Joseph T. Baroldi IONS Common Stock Sale -32.8% $170,808 $80.42 -2,124 4,347 03 Mar 2026 by Spouse
Joseph T. Baroldi IONS Common Stock Options Exercise 35.6% 1,699 6,471 03 Mar 2026 by Spouse
Joseph T. Baroldi IONS Common Stock Sale -9.02% $325,059 $79.36 -4,096 41,317 03 Mar 2026 Direct
Joseph T. Baroldi IONS Non-Qualified Stock Option (right to buy) Options Exercise -46.3% -1,699 1,970 03 Mar 2026 by Spouse
Eric Swayze IONS Common Stock Other 0.8% 256 32,361 27 Feb 2026 Direct
Patrick R. O'Neil IONS Common Stock Other 0.52% 376 72,359 27 Feb 2026 Direct
Brett P. Monia IONS Common Stock Other 0.19% 484 254,981 27 Feb 2026 Direct
Brian Birchler IONS Common Stock Other 0.53% 351 66,598 27 Feb 2026 Direct
C. Frank Bennett IONS Common Stock Other 0.26% 261 100,554 27 Feb 2026 Direct
Eric Swayze IONS Common Stock Sale -32.8% $1,278,914 $81.76 -15,642 32,105 13 Feb 2026 Direct
B. Lynne Parshall IONS Common Stock Sale -8.15% $413,588 $82.72 -5,000 56,344 11 Feb 2026 Direct
Brett P. Monia IONS Common Stock Sale -10.4% $2,524,820 $85.79 -29,430 254,497 06 Feb 2026 Direct
C. Frank Bennett IONS Common Stock Other 0 100,293 02 Feb 2026 Direct
Brian Birchler IONS Common Stock Sale -8.53% $513,048 $83.03 -6,179 66,247 30 Jan 2026 Direct
Eugene Schneider IONS Common Stock Sale -8.14% $515,630 $83.45 -6,179 69,702 30 Jan 2026 Direct
Joseph T. Baroldi IONS Common Stock Sale -10.4% $439,364 $82.96 -5,296 45,413 30 Jan 2026 Direct
Eric Swayze IONS Common Stock Sale -11.5% $512,446 $82.93 -6,179 47,747 30 Jan 2026 Direct
Patrick R. O'Neil IONS Common Stock Sale -7.91% $516,154 $83.53 -6,179 71,983 30 Jan 2026 Direct
Brett P. Monia IONS Common Stock Sale -18.2% $5,208,979 $82.72 -62,970 283,927 30 Jan 2026 Direct
* An asterisk sign (*) next to the price indicates that the price is likely invalid.