IONIS PHARMACEUTICALS INC - Common Stock (IONS)
CUSIP: 462222100
Q2 2025 13F Holders as of 30 Jun 2025
- Type / Class
- Equity / Common Stock
- Shares outstanding
- 165,242,218
- Total 13F shares
- 168,850,675
- Share change
- +3,044,039
- Total reported value
- $6,672,661,270
- Put/Call ratio
- 47%
- Price per share
- $39.51
- Number of holders
- 360
- Value change
- +$162,663,034
- Number of buys
- 200
- Number of sells
- 167
Quarterly Holders Quick Answers
What is CUSIP 462222100?
CUSIP 462222100 identifies IONS - IONIS PHARMACEUTICALS INC - Common Stock in SEC institutional holdings data.
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Recent filing periods for CUSIP 462222100:
Top shareholders of IONS - IONIS PHARMACEUTICALS INC - Common Stock (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| FMR LLC |
13F
|
Company |
14%
|
23,613,585
|
$712,421,869 | — | 31 Mar 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
9.9%
|
16,383,934
|
$494,303,288 | — | 31 Mar 2025 | |
| T. Rowe Price Investment Management, Inc. |
13F
|
Company |
9.8%
|
16,175,533
|
$488,016,000 | — | 31 Mar 2025 | |
| Capital World Investors |
13F
|
Company |
7.5%
|
12,361,994
|
$372,961,359 | — | 31 Mar 2025 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
5.7%
from 13D/G
|
11,264,442
|
$339,848,216 | — | 31 Mar 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
13F
|
Company |
4.3%
|
6,879,873
|
$284,413,950 | $0 | 30 Jun 2025 | |
| Bellevue Group AG |
13F
|
Company |
4.8%
|
7,853,198
|
$236,930,984 | — | 31 Mar 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.9%
|
4,845,133
|
$146,177,663 | — | 31 Mar 2025 | |
| Deep Track Capital, LP |
13F
|
Company |
2.8%
|
4,564,207
|
$137,702,125 | — | 31 Mar 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
2.1%
|
3,480,062
|
$104,993,471 | — | 31 Mar 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2%
|
3,265,034
|
$98,507,000 | — | 31 Mar 2025 | |
| Tweedy, Browne Co LLC |
13F
|
Company |
1.8%
|
2,983,518
|
$90,012,738 | — | 31 Mar 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.7%
|
2,842,954
|
$85,799,280 | — | 31 Mar 2025 | |
| ORBIMED ADVISORS LLC |
13F
|
Company |
1.5%
|
2,540,136
|
$76,635,903 | — | 31 Mar 2025 | |
| TWO SIGMA ADVISERS, LP |
13F
|
Company |
1.3%
|
2,092,011
|
$63,115,972 | — | 31 Mar 2025 | |
| BVF INC/IL |
13F
|
Company |
1.2%
|
1,913,385
|
$57,726,825 | — | 31 Mar 2025 | |
| UBS Group AG |
13F
|
Company |
1.1%
|
1,890,602
|
$57,039,462 | — | 31 Mar 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
1%
|
1,685,853
|
$50,862,185 | — | 31 Mar 2025 | |
| MACQUARIE GROUP LTD |
13F
|
Company |
1%
|
1,667,194
|
$50,299,000 | — | 31 Mar 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.87%
|
1,443,629
|
$43,554,287 | — | 31 Mar 2025 | |
| BNP Paribas Asset Management Holding S.A. |
13F
|
Company |
0.72%
|
1,196,392
|
$36,095,000 | — | 31 Mar 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.69%
|
1,144,181
|
$34,520,042 | — | 31 Mar 2025 | |
| TD ASSET MANAGEMENT INC |
13F
|
Company |
0.67%
|
1,100,466
|
$33,201,059 | — | 31 Mar 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.65%
|
1,075,600
|
$32,450,852 | — | 31 Mar 2025 | |
| Hudson Bay Capital Management LP |
13F
|
Company |
0.64%
|
1,049,900
|
$31,675,483 | — | 31 Mar 2025 | |
| ARK Investment Management LLC |
13F
|
Company |
0.61%
|
1,000,527
|
$30,185,886 | — | 31 Mar 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.6%
|
993,704
|
$29,980,050 | — | 31 Mar 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.53%
|
874,834
|
$26,393,741 | — | 31 Mar 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.51%
|
834,847
|
$25,187,334 | — | 31 Mar 2025 | |
| BANK OF MONTREAL /CAN/ |
13F
|
Company |
0.47%
|
782,835
|
$23,618,131 | — | 31 Mar 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.46%
|
767,432
|
$23,153,424 | — | 31 Mar 2025 | |
| Camber Capital Management LP |
13F
|
Company |
0.44%
|
725,000
|
$21,873,250 | — | 31 Mar 2025 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.4%
|
659,435
|
$19,895,152 | — | 31 Mar 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.39%
|
652,518
|
$19,686,467 | — | 31 Mar 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.37%
|
618,550
|
$19,248,586 | — | 31 Mar 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.38%
|
635,370
|
$19,169,113 | — | 31 Mar 2025 | |
| ROYAL BANK OF CANADA |
13F
|
Company |
0.37%
|
616,081
|
$18,588,000 | — | 31 Mar 2025 | |
| PINNACLE ASSOCIATES LTD |
13F
|
Company |
0.37%
|
608,517
|
$18,358,958 | — | 31 Mar 2025 | |
| Asset Managment Groupama |
13F
|
Individual |
0.34%
|
569,211
|
$17,730,923 | — | 31 Mar 2025 | |
| AXA S.A. |
13F
|
Company |
0.34%
|
566,486
|
$17,090,883 | — | 31 Mar 2025 | |
| Schonfeld Strategic Advisors LLC |
13F
|
Company |
0.34%
|
560,359
|
$16,906,029 | — | 31 Mar 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.33%
|
544,633
|
$16,431,584 | — | 31 Mar 2025 | |
| Eversept Partners, LP |
13F
|
Company |
0.31%
|
517,021
|
$15,598,524 | — | 31 Mar 2025 | |
| TEACHER RETIREMENT SYSTEM OF TEXAS |
13F
|
Company |
0.3%
|
500,451
|
$15,098,608 | — | 31 Mar 2025 | |
| Aberdeen Group plc |
13F
|
Company |
0.27%
|
446,197
|
$13,499,690 | — | 31 Mar 2025 | |
| CITIGROUP INC |
13F
|
Company |
0.26%
|
426,480
|
$12,866,901 | — | 31 Mar 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.26%
|
421,511
|
$12,716,987 | — | 31 Mar 2025 | |
| C WorldWide Group Holding A/S |
13F
|
Company |
0.24%
|
400,000
|
$12,068,000 | — | 31 Mar 2025 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.23%
|
377,204
|
$11,380,245 | — | 31 Mar 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.22%
|
360,188
|
$10,866,871 | — | 31 Mar 2025 |
Institutional Holders of IONIS PHARMACEUTICALS INC - Common Stock (IONS) as of Q2 2025
As of 30 Jun 2025,
IONIS PHARMACEUTICALS INC - Common Stock (IONS) was held by
360 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
168,850,675 shares.
The largest 10 holders included
FMR LLC, VANGUARD GROUP INC, T. Rowe Price Investment Management, Inc., Capital World Investors, BlackRock, Inc., Bellevue Group AG, WELLINGTON MANAGEMENT GROUP LLP, Deep Track Capital, LP, STATE STREET CORP, and ADAGE CAPITAL PARTNERS GP, L.L.C..
This page lists
361
institutional shareholders reporting positions in this security
for the Q2 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q2 2025 vs Q1 2025 Across Filers
Q1 2025 holders
340
Q2 2025 holders
360
Holder diff
20
| Investor | Q1 2025 Shares | Q2 2025 Shares | Share Diff | Share Chg % | Q1 2025 Value $ | Q2 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.