Security key
462222100
IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS)
CUSIP: 462222100
Q4 2022 13F Holders as of 31 Dec 2022
- Security type / class
- Equity / COMMON STOCK
- Total 13F shares
- 130,693,455
- Total 13F value
- $4,936,957,475
- Share change
- +4,435,022
- Put/Call ratio
- 65%
- SEC-reported price per share
- $37.77
- Number of holders
- 333
- Value change
- +$160,016,480
- Number of buys
- 157
- Number of sells
- 153
- Shares outstanding
- 166,460,189
Holder snapshot
7 signals
Open additional details 1 more signal available
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q4 2022
Institutions
333
Top holders
10
IONS full security history
Ownership snapshot
Full 13F holder table
Newer quarter: Q1 2023
Previous quarter: Q3 2022
IONIS PHARMACEUTICALS INC SEC filings
IONIS PHARMACEUTICALS INC company facts
Broader feeds
Reporting periods
Holder history for CUSIP 462222100
Recent filing periods:
Ownership snapshot
Top reported holders of IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
FMR LLC
Disclosed value leader
FMR LLC
Comparable rows
15/15
Latest evidence
30 Sep 2022
13F
Lead comparable stake: 13%
Showing 1-6 of 15 holder rows.
Quick read
FMR LLC leads the comparable SEC ownership view at 13%.
15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens FMR LLC's linked filing trail.
Comparable ownership
Top 5
FMR LLC
13%
VANGUARD GROUP INC
7.7%
T. Rowe Price Investment Manageme...
6.7%
Bellevue Group AG
5.7%
BlackRock Finance, Inc.
5.4%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-6 of 15 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| FMR LLC |
13F
Company
|
13%
|
$941,708,000
21,291,159 shares
|
— | 30 Sep 2022 |
| VANGUARD GROUP INC |
13F
Company
|
7.7%
|
$566,411,000
12,806,023 shares
|
— | 30 Sep 2022 |
| T. Rowe Price Investment Management, Inc. |
13F
Company
|
6.7%
|
$493,461,000
11,156,695 shares
|
— | 30 Sep 2022 |
| Bellevue Group AG |
13F
Company
|
5.7%
|
$418,566,000
9,463,400 shares
|
— | 30 Sep 2022 |
| BlackRock Finance, Inc. |
13F
Company
|
5.4%
|
$395,240,000
8,936,062 shares
|
— | 30 Sep 2022 |
| Clearbridge Investments, LLC |
13F
Company
|
3.5%
|
$255,379,000
5,773,892 shares
|
— | 30 Sep 2022 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q4 2022
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
333
Shares
130,693,455
Rows available
333
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q4 2022 vs Q3 2022 Across Filers
Q3 2022 holders
335
Q4 2022 holders
333
Holder diff
-2
| Investor | Q3 2022 Shares | Q4 2022 Shares | Share Diff | Share Chg % | Q3 2022 value | Q4 2022 value | Value change | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend