What does CUSIP 462222100 represent in this 13F holders report?

CUSIP 462222100 is the security identifier for IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK used to aggregate holder disclosures.

How many institutions held IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK in Q4 2019?

378 institutional investors reported IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK for Q4 2019. Use the holders table for investor-level position and value details.

IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS)

CUSIP: 462222100

Q4 2019 13F Holders as of 31 Dec 2019

Type / Class: Equity / COMMON STOCK
Shares outstanding: 166,460,189
Total 13F shares: 120,722,063
Share change: -1,426,130
Total reported value: $7,295,059,529
Put/Call ratio: 151%
Price per share: $60.41
Number of holders: 378
Value change: -$83,490,703
Number of buys: 157
Number of sells: 169

Quarterly Holders Quick Answers

What is CUSIP 462222100?
CUSIP 462222100 identifies IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2020
Previous quarter: Q3 2019

Recent filing periods for CUSIP 462222100:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of IONS - IONIS PHARMACEUTICALS INC - COMMON STOCK (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	13%	20,935,783	$1,254,263,000	—	30 Sep 2019	13F
VANGUARD GROUP INC	13F	Company	7.3%	12,214,475	$731,769,000	—	30 Sep 2019	13F
Clearbridge Investments, LLC	13F	Company	5.6%	9,290,924	$556,619,000	—	30 Sep 2019	13F
BAILLIE GIFFORD & CO	13F	Company	5.1%	8,415,289	$504,160,000	—	30 Sep 2019	13F
BlackRock Finance, Inc.	13F	Company	5%	8,350,799	$500,297,000	—	30 Sep 2019	13F
Bellevue Group AG	13F	Company	5%	8,321,914	$498,566,000	—	30 Sep 2019	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	4.7%	7,745,339	$464,023,000	—	30 Sep 2019	13F
STATE STREET CORP	13F	Company	2.2%	3,650,783	$218,718,000	—	30 Sep 2019	13F
WADDELL & REED FINANCIAL INC	13F	Company	1.9%	3,180,078	$190,518,000	—	30 Sep 2019	13F
Invesco Ltd.	13F	Company	1.4%	2,376,663	$142,387,000	—	30 Sep 2019	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	1.2%	1,949,864	$116,816,000	—	30 Sep 2019	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	1.1%	1,813,011	$108,617,000	—	30 Sep 2019	13F
TWO SIGMA ADVISERS, LP	13F	Company	0.97%	1,614,411	$96,719,000	—	30 Sep 2019	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.86%	1,428,037	$85,494,000	—	30 Sep 2019	13F
NORGES BANK	13F	Company	0.84%	1,395,397	$83,599,000	—	30 Sep 2019	13F
AMERICAN CENTURY COMPANIES INC	13F	Company	0.82%	1,371,814	$82,185,000	—	30 Sep 2019	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.63%	1,040,580	$62,342,000	—	30 Sep 2019	13F
FIRST TRUST ADVISORS LP	13F	Company	0.59%	988,916	$59,246,000	—	30 Sep 2019	13F
BVF INC/IL	13F	Company	0.56%	935,548	$56,049,000	—	30 Sep 2019	13F
Sumitomo Mitsui Trust Group, Inc.	13F	Company	0.52%	865,463	$51,850,000	—	30 Sep 2019	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.5%	830,460	$49,753,000	—	30 Sep 2019	13F
D. E. Shaw & Co., Inc.	13F	Company	0.5%	829,490	$49,695,000	—	30 Sep 2019	13F
NORTHERN TRUST CORP	13F	Company	0.48%	799,258	$47,883,000	—	30 Sep 2019	13F
PINNACLE ASSOCIATES LTD	13F	Company	0.46%	767,960	$46,008,000	—	30 Sep 2019	13F
RAYMOND JAMES & ASSOCIATES	13F	Company	0.44%	732,804	$43,902,000	—	30 Sep 2019	13F
DOWLING & YAHNKE LLC	13F	Company	0.41%	675,478	$40,468,000	—	30 Sep 2019	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.4%	661,005	$39,601,000	—	30 Sep 2019	13F
APG Asset Management N.V.	13F	Company	0.4%	669,687	$36,801,000	—	30 Sep 2019	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.35%	588,099	$35,234,000	—	30 Sep 2019	13F
JANUS HENDERSON GROUP PLC	13F	Company	0.35%	582,531	$34,900,000	—	30 Sep 2019	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.34%	570,229	$34,162,000	—	30 Sep 2019	13F
Bank of New York Mellon Corp	13F	Company	0.33%	547,235	$32,786,000	—	30 Sep 2019	13F
Nuveen Asset Management, LLC	13F	Company	0.3%	499,187	$29,907,000	—	30 Sep 2019	13F
Mitsubishi UFJ Trust & Banking Corp	13F	Company	0.29%	475,511	$28,488,000	—	30 Sep 2019	13F
Swiss National Bank	13F	Company	0.26%	440,159	$26,370,000	—	30 Sep 2019	13F
Sicart Associates LLC	13F	Company	0.25%	410,537	$24,595,000	—	30 Sep 2019	13F
TOCQUEVILLE ASSET MANAGEMENT L.P.	13F	Company	0.25%	409,307	$24,522,000	—	30 Sep 2019	13F
STIFEL FINANCIAL CORP	13F	Company	0.24%	406,739	$24,362,000	—	30 Sep 2019	13F
Legal & General Group Plc	13F	Company	0.23%	390,248	$23,372,000	—	30 Sep 2019	13F
Amova Asset Management Americas, Inc.	13F	Company	0.22%	364,091	$21,813,000	—	30 Sep 2019	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	0.2%	337,234	$20,203,689	—	30 Sep 2019	13F
First Light Asset Management, LLC	13F	Company	0.2%	324,649	$19,450,000	—	30 Sep 2019	13F
S.c.a. Candriam	13F	Individual	0.18%	293,200	$17,566,000	—	30 Sep 2019	13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	13F	Company	0.18%	291,371	$17,456,000	—	30 Sep 2019	13F
ALTRINSIC GLOBAL ADVISORS LLC	13F	Company	0.17%	289,198	$17,326,000	—	30 Sep 2019	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.17%	280,785	$16,820,000	—	30 Sep 2019	13F
NEW YORK STATE COMMON RETIREMENT FUND	13F	Company	0.16%	271,673	$16,276,000	—	30 Sep 2019	13F
GREAT POINT PARTNERS LLC	13F	Company	0.16%	270,000	$16,176,000	—	30 Sep 2019	13F
AXA S.A.	13F	Company	0.16%	264,122	$15,824,000	—	30 Sep 2019	13F
FRANKLIN RESOURCES INC	13F	Company	0.16%	263,600	$15,792,000	—	30 Sep 2019	13F

Institutional Holders of IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) as of Q4 2019

As of 31 Dec 2019, IONIS PHARMACEUTICALS INC - COMMON STOCK (IONS) was held by 378 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 120,722,063 shares. The largest 10 holders included FMR LLC, VANGUARD GROUP INC, BAILLIE GIFFORD & CO, Bellevue Group AG, BlackRock Inc., Clearbridge Investments, LLC, WELLINGTON MANAGEMENT GROUP LLP, STATE STREET CORP, Invesco Ltd., and WADDELL & REED FINANCIAL INC. This page lists 378 institutional shareholders reporting positions in this security for the Q4 2019 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2019 vs Q3 2019 Across Filers

Q3 2019 holders

359

Q4 2019 holders

378

Holder diff

Investor	Q3 2019 Shares	Q4 2019 Shares	Share Diff	Share Chg %	Q3 2019 Value $	Q4 2019 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.