What does CUSIP 462222100 represent in this 13F holders report?

CUSIP 462222100 is the security identifier for IONS - IONIS PHARMACEUTICALS INC - Common Stock used to aggregate holder disclosures.

How many institutions held IONS - IONIS PHARMACEUTICALS INC - Common Stock in Q2 2019?

384 institutional investors reported IONS - IONIS PHARMACEUTICALS INC - Common Stock for Q2 2019. Use the holders table for investor-level position and value details.

IONIS PHARMACEUTICALS INC - Common Stock (IONS)

CUSIP: 462222100

Q2 2019 13F Holders as of 30 Jun 2019

Type / Class: Equity / Common Stock
Shares outstanding: 162,643,196
Total 13F shares: 126,579,263
Share change: +19,324,513
Total reported value: $8,133,847,761
Put/Call ratio: 169%
Price per share: $64.27
Number of holders: 384
Value change: +$1,221,346,949
Number of buys: 231
Number of sells: 145

Quarterly Holders Quick Answers

What is CUSIP 462222100?
CUSIP 462222100 identifies IONS - IONIS PHARMACEUTICALS INC - Common Stock in SEC institutional holdings data.

Need full ownership history?
Open the full security ownership history page.

Next holder-history checks

These links keep the next click tied to holder verification, nearby quarters, or outside-13F ownership context.

Back to full security ownership history for the broader multi-quarter picture.
Latest 13F filings for newly reported positions across managers.
Latest Schedule 13D/13G reports for ownership changes outside the 13F cadence.
SEC investors directory for manager drilldown.

Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q3 2019
Previous quarter: Q1 2019

Recent filing periods for CUSIP 462222100:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of IONS - IONIS PHARMACEUTICALS INC - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	13%	20,633,697	$1,674,837,000	—	31 Mar 2019	13F
VANGUARD GROUP INC	13F	Company	7.7%	12,473,515	$1,012,475,000	—	31 Mar 2019	13F
Clearbridge Investments, LLC	13F	Company	5.8%	9,498,310	$770,978,000	—	31 Mar 2019	13F
BAILLIE GIFFORD & CO	13F	Company	5.3%	8,644,351	$701,663,000	—	31 Mar 2019	13F
BB BIOTECH AG	13F	Company	4.7%	7,725,000	$627,038,000	—	31 Mar 2019	13F
BlackRock Finance, Inc.	13F	Company	4.7%	7,621,572	$618,644,000	—	31 Mar 2019	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	4.6%	7,539,076	$611,947,000	—	31 Mar 2019	13F
WADDELL & REED FINANCIAL INC	13F	Company	2.1%	3,362,306	$272,918,000	—	31 Mar 2019	13F
FIRST TRUST ADVISORS LP	13F	Company	1.6%	2,591,839	$210,380,000	—	31 Mar 2019	13F
STATE STREET CORP	13F	Company	1.6%	2,553,088	$207,234,000	—	31 Mar 2019	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	1.5%	2,467,469	$200,284,000	—	31 Mar 2019	13F
OppenheimerFunds, Inc.	13F	Company	1.2%	2,027,449	$164,568,000	—	31 Mar 2019	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.87%	1,416,922	$115,011,000	—	31 Mar 2019	13F
NORGES BANK	13F	Company	0.83%	1,342,776	$108,994,000	—	31 Mar 2019	13F
AMERICAN CENTURY COMPANIES INC	13F	Company	0.8%	1,300,380	$105,552,000	—	31 Mar 2019	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.63%	1,016,637	$82,521,000	—	31 Mar 2019	13F
PINNACLE ASSOCIATES LTD	13F	Company	0.54%	878,031	$71,270,000	—	31 Mar 2019	13F
TWO SIGMA ADVISERS, LP	13F	Company	0.5%	806,911	$65,497,000	—	31 Mar 2019	13F
RAYMOND JAMES & ASSOCIATES	13F	Company	0.49%	795,317	$64,556,000	—	31 Mar 2019	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.48%	786,410	$63,833,000	—	31 Mar 2019	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.46%	748,544	$60,759,000	—	31 Mar 2019	13F
DOWLING & YAHNKE LLC	13F	Company	0.42%	675,478	$54,829,000	—	31 Mar 2019	13F
NORTHERN TRUST CORP	13F	Company	0.4%	652,571	$52,969,000	—	31 Mar 2019	13F
First Light Asset Management, LLC	13F	Company	0.38%	611,162	$49,608,000	—	31 Mar 2019	13F
Motley Fool Wealth Management, LLC	13F	Company	0.37%	608,212	$49,369,000	—	31 Mar 2019	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.36%	582,516	$47,283,000	—	31 Mar 2019	13F
D. E. Shaw & Co., Inc.	13F	Company	0.34%	557,191	$45,227,000	—	31 Mar 2019	13F
Bank of New York Mellon Corp	13F	Company	0.32%	519,057	$42,131,000	—	31 Mar 2019	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.3%	491,876	$39,926,000	—	31 Mar 2019	13F
STIFEL FINANCIAL CORP	13F	Company	0.29%	470,899	$38,196,000	—	31 Mar 2019	13F
TOCQUEVILLE ASSET MANAGEMENT L.P.	13F	Company	0.28%	450,794	$36,591,000	—	31 Mar 2019	13F
FRANKLIN RESOURCES INC	13F	Company	0.26%	418,000	$33,929,000	—	31 Mar 2019	13F
Sicart Associates LLC	13F	Company	0.26%	416,985	$33,847,000	—	31 Mar 2019	13F
AQR CAPITAL MANAGEMENT LLC	13F	Company	0.25%	411,874	$33,024,000	—	31 Mar 2019	13F
S.c.a. Candriam	13F	Individual	0.24%	393,200	$31,917,000	—	31 Mar 2019	13F
CANADA PENSION PLAN INVESTMENT BOARD	13F	Company	0.24%	388,255	$31,515,000	—	31 Mar 2019	13F
MORGAN STANLEY	13F	Company	0.24%	387,002	$31,412,000	—	31 Mar 2019	13F
Mitsubishi UFJ Trust & Banking Corp	13F	Company	0.23%	370,170	$30,047,000	—	31 Mar 2019	13F
CREDIT SUISSE AG/	13F	Company	0.21%	349,319	$28,354,000	—	31 Mar 2019	13F
PDT Partners, LLC	13F	Company	0.21%	341,800	$27,744,000	—	31 Mar 2019	13F
AXA S.A.	13F	Company	0.19%	304,787	$24,740,000	—	31 Mar 2019	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.19%	304,577	$24,720,000	—	31 Mar 2019	13F
Bellevue Group AG	13F	Company	0.19%	302,643	$24,566,000	—	31 Mar 2019	13F
SCOUT INVESTMENTS, INC.	13F	Company	0.18%	297,815	$24,174,000	—	31 Mar 2019	13F
NEW YORK STATE COMMON RETIREMENT FUND	13F	Company	0.18%	297,623	$24,158,000	—	31 Mar 2019	13F
ROTHSCHILD & CO ASSET MANAGEMENT US INC.	13F	Company	0.18%	287,276	$23,318,000	—	31 Mar 2019	13F
FEDERATED HERMES, INC.	13F	Company	0.16%	267,878	$21,744,000	—	31 Mar 2019	13F
Swiss National Bank	13F	Company	0.15%	238,100	$19,327,000	—	31 Mar 2019	13F
ALTRINSIC GLOBAL ADVISORS LLC	13F	Company	0.15%	237,645	$19,290,000	—	31 Mar 2019	13F
Gamma As Sector	13F	Individual	0.14%	233,714	$18,971,000	—	31 Mar 2019	13F

Institutional Holders of IONIS PHARMACEUTICALS INC - Common Stock (IONS) as of Q2 2019

As of 30 Jun 2019, IONIS PHARMACEUTICALS INC - Common Stock (IONS) was held by 384 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 126,579,263 shares. The largest 10 holders included FMR LLC, VANGUARD GROUP INC, Clearbridge Investments, LLC, BlackRock Inc., BAILLIE GIFFORD & CO, Bellevue Group AG, WELLINGTON MANAGEMENT GROUP LLP, STATE STREET CORP, WADDELL & REED FINANCIAL INC, and Invesco Ltd.. This page lists 385 institutional shareholders reporting positions in this security for the Q2 2019 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q2 2019 vs Q1 2019 Across Filers

Q1 2019 holders

381

Q2 2019 holders

384

Holder diff

Investor	Q1 2019 Shares	Q2 2019 Shares	Share Diff	Share Chg %	Q1 2019 Value $	Q2 2019 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.