What does CUSIP 462222100 represent in this 13F holders report?

CUSIP 462222100 is the security identifier for IONS - IONIS PHARMACEUTICALS INC - Common Stock used to aggregate holder disclosures.

How many institutions held IONS - IONIS PHARMACEUTICALS INC - Common Stock in Q1 2018?

316 institutional investors reported IONS - IONIS PHARMACEUTICALS INC - Common Stock for Q1 2018. Use the holders table for investor-level position and value details.

IONIS PHARMACEUTICALS INC - Common Stock (IONS)

CUSIP: 462222100

Q1 2018 13F Holders as of 31 Mar 2018

Type / Class: Equity / Common Stock
Shares outstanding: 165,242,218
Total 13F shares: 115,119,301
Share change: +1,438,658
Total reported value: $5,074,956,068
Put/Call ratio: 96%
Price per share: $44.08
Number of holders: 316
Value change: +$57,031,375
Number of buys: 160
Number of sells: 137

Quarterly Holders Quick Answers

What is CUSIP 462222100?
CUSIP 462222100 identifies IONS - IONIS PHARMACEUTICALS INC - Common Stock in SEC institutional holdings data.

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Explore More Reporting Periods

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Newer quarter: Q2 2018
Previous quarter: Q4 2017

Recent filing periods for CUSIP 462222100:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of IONS - IONIS PHARMACEUTICALS INC - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	11%	18,719,325	$941,582,000	—	31 Dec 2017	13F
Clearbridge Investments, LLC	13F	Company	6.6%	10,984,818	$552,536,000	—	31 Dec 2017	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	6.6%	10,897,033	$548,120,000	—	31 Dec 2017	13F
VANGUARD GROUP INC	13F	Company	6.1%	10,106,212	$508,343,000	—	31 Dec 2017	13F
BB BIOTECH AG	13F	Company	4.9%	8,136,334	$409,258,000	—	31 Dec 2017	13F
BlackRock Finance, Inc.	13F	Company	4.2%	6,972,606	$350,722,000	—	31 Dec 2017	13F
BAILLIE GIFFORD & CO	13F	Company	4%	6,612,301	$332,599,000	—	31 Dec 2017	13F
WADDELL & REED FINANCIAL INC	13F	Company	2.7%	4,530,100	$227,865,000	—	31 Dec 2017	13F
STATE STREET CORP	13F	Company	1.7%	2,752,542	$138,454,000	—	31 Dec 2017	13F
OppenheimerFunds, Inc.	13F	Company	1.6%	2,689,981	$135,306,000	—	31 Dec 2017	13F
GOLDMAN SACHS GROUP INC	13F	Company	1.2%	1,928,898	$97,024,000	—	31 Dec 2017	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	0.84%	1,388,578	$69,845,000	—	31 Dec 2017	13F
PINNACLE ASSOCIATES LTD	13F	Company	0.78%	1,289,221	$64,848,000	—	31 Dec 2017	13F
AMERICAN CENTURY COMPANIES INC	13F	Company	0.71%	1,181,109	$59,410,000	—	31 Dec 2017	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.67%	1,103,329	$55,497,000	—	31 Dec 2017	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.65%	1,074,130	$54,028,000	—	31 Dec 2017	13F
FIRST TRUST ADVISORS LP	13F	Company	0.56%	932,021	$46,881,000	—	31 Dec 2017	13F
TOCQUEVILLE ASSET MANAGEMENT L.P.	13F	Company	0.51%	841,724	$42,339,000	—	31 Dec 2017	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.51%	835,509	$42,027,000	—	31 Dec 2017	13F
NORGES BANK	13F	Company	0.48%	798,371	$40,158,000	—	31 Dec 2017	13F
RAYMOND JAMES & ASSOCIATES	13F	Company	0.47%	777,449	$39,106,000	—	31 Dec 2017	13F
FRANKLIN RESOURCES INC	13F	Company	0.45%	750,666	$37,759,000	—	31 Dec 2017	13F
DOWLING & YAHNKE LLC	13F	Company	0.41%	675,891	$33,997,000	—	31 Dec 2017	13F
FARALLON CAPITAL MANAGEMENT LLC	13F	Company	0.39%	645,000	$32,444,000	—	31 Dec 2017	13F
STIFEL FINANCIAL CORP	13F	Company	0.37%	609,559	$30,687,000	—	31 Dec 2017	13F
Fiera Capital Corp	13F	Company	0.37%	608,864	$30,626,000	—	31 Dec 2017	13F
NORTHERN TRUST CORP	13F	Company	0.36%	586,982	$29,525,000	—	31 Dec 2017	13F
Bank of New York Mellon Corp	13F	Company	0.33%	540,876	$27,206,000	—	31 Dec 2017	13F
ALTRINSIC GLOBAL ADVISORS LLC	13F	Company	0.28%	464,560	$23,367,000	—	31 Dec 2017	13F
CREDIT SUISSE AG/	13F	Company	0.27%	452,939	$22,783,000	—	31 Dec 2017	13F
Boxer Capital, LLC	13F	Company	0.27%	450,000	$22,635,000	—	31 Dec 2017	13F
ROYAL BANK OF CANADA	13F	Company	0.25%	415,425	$20,897,000	—	31 Dec 2017	13F
PDT Partners, LLC	13F	Company	0.25%	406,361	$20,440,000	—	31 Dec 2017	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.24%	401,980	$20,220,000	—	31 Dec 2017	13F
Sicart Associates LLC	13F	Company	0.24%	398,072	$20,023,000	—	31 Dec 2017	13F
NEW YORK STATE COMMON RETIREMENT FUND	13F	Company	0.23%	386,000	$19,416,000	—	31 Dec 2017	13F
ARK Investment Management LLC	13F	Company	0.22%	370,835	$18,653,000	—	31 Dec 2017	13F
Mitsubishi UFJ Trust & Banking Corp	13F	Company	0.22%	359,750	$18,095,000	—	31 Dec 2017	13F
Motley Fool Wealth Management, LLC	13F	Company	0.2%	329,328	$16,565,000	—	31 Dec 2017	13F
TIAA CREF INVESTMENT MANAGEMENT LLC	13F	Company	0.19%	321,178	$16,155,000	—	31 Dec 2017	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	0.17%	286,517	$14,411,805	—	31 Dec 2017	13F
ROTHSCHILD & CO ASSET MANAGEMENT US INC.	13F	Company	0.17%	283,177	$14,244,000	—	31 Dec 2017	13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	13F	Company	0.16%	266,300	$13,395,000	—	31 Dec 2017	13F
Motley Fool Asset Management LLC	13F	Company	0.16%	259,100	$13,033,000	—	31 Dec 2017	13F
Bellevue Group AG	13F	Company	0.16%	256,706	$12,908,000	—	31 Dec 2017	13F
EDMOND DE ROTHSCHILD HOLDING S.A.	13F	Company	0.15%	240,098	$12,077,000	—	31 Dec 2017	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.14%	224,811	$11,309,000	—	31 Dec 2017	13F
Invesco Ltd.	13F	Company	0.13%	221,506	$11,142,000	—	31 Dec 2017	13F
AVIVA PLC	13F	Company	0.13%	213,524	$10,740,000	—	31 Dec 2017	13F
Swiss National Bank	13F	Company	0.13%	211,800	$10,654,000	—	31 Dec 2017	13F

Institutional Holders of IONIS PHARMACEUTICALS INC - Common Stock (IONS) as of Q1 2018

As of 31 Mar 2018, IONIS PHARMACEUTICALS INC - Common Stock (IONS) was held by 316 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 115,119,301 shares. The largest 10 holders included FMR LLC, Clearbridge Investments, LLC, VANGUARD GROUP INC, WELLINGTON MANAGEMENT GROUP LLP, BB BIOTECH AG, BlackRock Inc., BAILLIE GIFFORD & CO, WADDELL & REED FINANCIAL INC, STATE STREET CORP, and OppenheimerFunds, Inc.. This page lists 316 institutional shareholders reporting positions in this security for the Q1 2018 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q1 2018 vs Q4 2017 Across Filers

Q4 2017 holders

308

Q1 2018 holders

316

Holder diff

Investor	Q4 2017 Shares	Q1 2018 Shares	Share Diff	Share Chg %	Q4 2017 Value $	Q1 2018 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.