Spyre Therapeutics, Inc. - Common Stock (SYRE)
CUSIP: 00773J202
Q2 2024 13F Holders as of 30 Jun 2024
- Type / Class
- Equity / Common Stock
- Shares outstanding
- 78,841,667
- Total 13F shares
- 50,382,939
- Share change
- +18,743,418
- Total reported value
- $1,184,222,119
- Put/Call ratio
- 58%
- Price per share
- $23.51
- Number of holders
- 106
- Value change
- +$421,575,660
- Number of buys
- 73
- Number of sells
- 39
Quarterly Holders Quick Answers
What is CUSIP 00773J202?
CUSIP 00773J202 identifies SYRE - Spyre Therapeutics, Inc. - Common Stock in SEC institutional holdings data.
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Recent filing periods for CUSIP 00773J202:
Top shareholders of SYRE - Spyre Therapeutics, Inc. - Common Stock (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| FMR LLC |
13F
|
Company |
8.4%
|
6,583,755
|
$246,560,995 | — | 31 Mar 2024 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
3.2%
|
2,556,679
|
$96,974,834 | — | 31 Mar 2024 | |
| RTW INVESTMENTS, LP |
13F
|
Company |
2.8%
|
2,232,760
|
$84,688,586 | — | 31 Mar 2024 | |
| VR Adviser, LLC |
13F
|
Company |
2.8%
|
2,171,782
|
$82,375,691 | — | 31 Mar 2024 | |
| Commodore Capital LP |
13F
|
Company |
2.4%
|
1,884,084
|
$71,463,306 | — | 31 Mar 2024 | |
| Avoro Capital Advisors LLC |
13F
|
Company |
2.3%
|
1,839,138
|
$69,758,504 | — | 31 Mar 2024 | |
| Deep Track Capital, LP |
13F
|
Company |
1.5%
|
1,213,420
|
$46,025,021 | — | 31 Mar 2024 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
1.4%
|
1,105,200
|
$41,920,236 | — | 31 Mar 2024 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
1%
|
812,860
|
$30,831,780 | — | 31 Mar 2024 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.94%
|
741,904
|
$28,140,419 | — | 31 Mar 2024 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.9%
|
707,590
|
$26,838,889 | — | 31 Mar 2024 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.87%
|
687,080
|
$26,060,944 | — | 31 Mar 2024 | |
| BlackRock Finance, Inc. |
13F
|
Company |
0.71%
|
556,691
|
$21,115,289 | — | 31 Mar 2024 | |
| BRAIDWELL LP |
13F
|
Company |
0.65%
|
515,000
|
$19,533,950 | — | 31 Mar 2024 | |
| Polar Capital Holdings Plc |
13F
|
Company |
0.63%
|
500,000
|
$18,965,000 | — | 31 Mar 2024 | |
| VANGUARD GROUP INC |
13F
|
Company |
0.63%
|
497,181
|
$18,858,075 | — | 31 Mar 2024 | |
| Darwin Global Management, Ltd. |
13F
|
Company |
0.6%
|
473,200
|
$17,948,476 | — | 31 Mar 2024 | |
| FARALLON CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.59%
|
466,000
|
$17,675,380 | — | 31 Mar 2024 | |
| First Turn Management, LLC |
13F
|
Company |
0.59%
|
464,435
|
$17,616,020 | — | 31 Mar 2024 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
0.52%
|
410,000
|
$15,551,300 | — | 31 Mar 2024 | |
| Fairmount Funds Management LLC |
13F
|
Company |
0.48%
|
378,421
|
$14,353,509 | — | 31 Mar 2024 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.42%
|
330,225
|
$12,529,455 | — | 31 Mar 2024 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.41%
|
319,563
|
$12,121,025 | — | 31 Mar 2024 | |
| Boxer Capital, LLC |
13F
|
Company |
0.32%
|
250,000
|
$9,482,500 | — | 31 Mar 2024 | |
| Cormorant Asset Management, LP |
13F
|
Company |
0.32%
|
250,000
|
$9,482,500 | — | 31 Mar 2024 | |
| Logos Global Management LP |
13F
|
Company |
0.32%
|
250,000
|
$9,482,500 | — | 31 Mar 2024 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.3%
|
239,915
|
$9,099,976 | — | 31 Mar 2024 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.24%
|
188,053
|
$7,132,850 | — | 31 Mar 2024 | |
| SUVRETTA CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.21%
|
162,395
|
$6,159,642 | — | 31 Mar 2024 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.21%
|
161,921
|
$6,141,664 | — | 31 Mar 2024 | |
| HighVista Strategies LLC |
13F
|
Company |
0.2%
|
154,381
|
$5,855,671 | — | 31 Mar 2024 | |
| Invesco Ltd. |
13F
|
Company |
0.19%
|
152,578
|
$5,787,283 | — | 31 Mar 2024 | |
| STATE STREET CORP |
13F
|
Company |
0.17%
|
134,426
|
$5,098,778 | — | 31 Mar 2024 | |
| GREAT POINT PARTNERS LLC |
13F
|
Company |
0.16%
|
125,000
|
$4,741,250 | — | 31 Mar 2024 | |
| Walleye Capital LLC |
13F
|
Company |
0.14%
|
111,478
|
$4,228,361 | — | 31 Mar 2024 | |
| S.c.a. Candriam |
13F
|
Individual |
0.13%
|
105,000
|
$3,982,650 | — | 31 Mar 2024 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.13%
|
101,503
|
$3,850,009 | — | 31 Mar 2024 | |
| Woodline Partners LP |
13F
|
Company |
0.13%
|
100,527
|
$3,812,989 | — | 31 Mar 2024 | |
| Ghost Tree Capital, LLC |
13F
|
Company |
0.13%
|
100,000
|
$3,793,000 | — | 31 Mar 2024 | |
| Integral Health Asset Management, LLC |
13F
|
Company |
0.13%
|
100,000
|
$3,793,000 | — | 31 Mar 2024 | |
| Nicholas Investment Partners, LP |
13F
|
Company |
0.11%
|
89,962
|
$3,412,259 | — | 31 Mar 2024 | |
| HRT FINANCIAL LP |
13F
|
Company |
0.1%
|
78,996
|
$2,996,000 | — | 31 Mar 2024 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
0.1%
|
78,529
|
$2,979,000 | — | 31 Mar 2024 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.08%
|
66,340
|
$2,516,276 | — | 31 Mar 2024 | |
| Assenagon Asset Management S.A. |
13F
|
Company |
0.08%
|
64,400
|
$2,442,692 | — | 31 Mar 2024 | |
| STEMPOINT CAPITAL LP |
13F
|
Company |
0.08%
|
62,253
|
$2,361,256 | — | 31 Mar 2024 | |
| TD ASSET MANAGEMENT INC |
13F
|
Company |
0.08%
|
60,968
|
$2,312,516 | — | 31 Mar 2024 | |
| Qube Research & Technologies Ltd |
13F
|
Company |
0.07%
|
57,678
|
$2,187,727 | — | 31 Mar 2024 | |
| MORGAN STANLEY |
13F
|
Company |
0.06%
|
51,188
|
$1,941,561 | — | 31 Mar 2024 | |
| ADAR1 Capital Management, LLC |
13F
|
Company |
0.06%
|
49,500
|
$1,877,535 | — | 31 Mar 2024 |
Institutional Holders of Spyre Therapeutics, Inc. - Common Stock (SYRE) as of Q2 2024
As of 30 Jun 2024,
Spyre Therapeutics, Inc. - Common Stock (SYRE) was held by
106 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
50,382,939 shares.
The largest 10 holders included
FMR LLC, Fairmount Funds Management LLC, RTW INVESTMENTS, LP, PERCEPTIVE ADVISORS LLC, VR Adviser, LLC, BRAIDWELL LP, BlackRock Inc., COMMODORE CAPITAL LP, VANGUARD GROUP INC, and Avoro Capital Advisors LLC.
This page lists
106
institutional shareholders reporting positions in this security
for the Q2 2024 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q2 2024 vs Q1 2024 Across Filers
Q1 2024 holders
101
Q2 2024 holders
106
Holder diff
5
| Investor | Q1 2024 Shares | Q2 2024 Shares | Share Diff | Share Chg % | Q1 2024 Value $ | Q2 2024 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.