How many institutions held SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value in Q2 2026?

4 institutional investors reported SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value for Q2 2026. Use the holders table for investor-level position and value details.

Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (SYRE)

Q: What does CUSIP 00773J202 represent in this 13F holders report?

CUSIP 00773J202 is the security identifier for SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value used to aggregate holder disclosures.

CUSIP: 00773J202

Q2 2026 13F Holders as of 30 Jun 2026

Security type / class: Equity / Common Stock, $0.0001 par value
Total 13F shares: 30,674
Total 13F value: $2,722,958
Share change: +6,342
SEC-reported price per share: $88.78
Number of holders: 4
Value change: +$1,277,804
Number of buys: 3
Number of sells: 3
Shares outstanding: 96,768,779

Security key

00773J202

Report period

Q2 2026

Institutions

Top holders

SYRE full security history Ownership snapshot Full 13F holder table Previous quarter: Q1 2026 Spyre Therapeutics, Inc. SEC filings Spyre Therapeutics, Inc. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 00773J202

Previous quarter: Q1 2026

Recent filing periods:

Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024

Ownership snapshot

Top reported holders of SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

Fairmount Funds Managemen...

Disclosed value leader

Fairmount Funds Managemen...

Comparable rows

15/15

Latest evidence

23 Jun 2026

13D/G 3/4/5 13F Lead comparable stake: 10% 13D/G row: Fairmount Funds Management LLC Showing 1-6 of 15 holder rows.

Quick read

Fairmount Funds Management LLC leads the comparable SEC ownership view at 10%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Fairmount Funds Management LLC's linked filing trail.

Comparable ownership Top 5

Fairmount Funds Management LLC 10%

BlackRock, Inc. 6.6%

RTW INVESTMENTS, LP 6.2%

PERCEPTIVE ADVISORS LLC 5%

Venrock Healthcare Capital Partne... 4.6%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
Fairmount Funds Management LLC	13D/G 3/4/5 13F Peter Evan Harwin · Director · Company 13D/G 3/4/5 13F	10%	$697,101,864 9,667,201 shares	+$46,907,483	23 Jun 2026
BlackRock, Inc.	13F 13D/G Company 13F 13D/G	6.6% from 13D/G	$278,490,385 5,521,221 shares	—	31 Mar 2026
RTW INVESTMENTS, LP	13F 13D/G Company 13F 13D/G	6.2% from 13D/G	$210,435,478 4,171,996 shares	—	31 Mar 2026
PERCEPTIVE ADVISORS LLC	13D/G 13F Company 13D/G 13F	5%	$217,875,378 4,319,496 shares	+$88,006,350	15 Apr 2026
Venrock Healthcare Capital Partners III, L.P.	13D/G 13D/G	4.6%	$40,335,429 2,685,448 shares	$0	31 Dec 2024
TANG CAPITAL MANAGEMENT LLC	13F 13D/G Company 13F 13D/G	2.4% from 13D/G	$95,442,568 1,892,200 shares	—	31 Mar 2026

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q2 2026

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

30,674

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q2 2026 vs Q1 2026 Across Filers

Q1 2026 holders

196

Q2 2026 holders

Holder diff

-192

Investor	Q1 2026 Shares	Q2 2026 Shares	Share Diff	Share Chg %	Q1 2026 value	Q2 2026 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend