Type / Class
Equity / Common Stock, par value $0.0001 per share
Shares outstanding
78,841,667
Total 13F shares
62,108,053
Share change
+2,172,589
Total reported value
$1,004,204,799
Put/Call ratio
58%
Price per share
$16.14
Number of holders
128
Value change
+$22,237,875
Number of buys
70
Number of sells
56

Institutional Holders of Spyre Therapeutics, Inc. - Common Stock, par value $0.0001 per share (SYRE) as of Q1 2025

As of 31 Mar 2025, Spyre Therapeutics, Inc. - Common Stock, par value $0.0001 per share (SYRE) was held by 128 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 62,108,053 shares. The largest 10 holders included FMR LLC, Fairmount Funds Management LLC, RTW INVESTMENTS, LP, BlackRock, Inc., VANGUARD GROUP INC, Driehaus Capital Management LLC, VR ADVISER, LLC, BRAIDWELL LP, Capital International Investors, and PERCEPTIVE ADVISORS LLC. This page lists 128 institutional shareholders reporting positions in this security for the Q1 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.