Security key
00773J202
Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (SYRE)
CUSIP: 00773J202
Q3 2024 13F Holders as of 30 Sep 2024
- Security type / class
- Equity / Common Stock, $0.0001 par value
- Total 13F shares
- 51,375,323
- Total 13F value
- $1,511,815,633
- Share change
- +732,563
- Put/Call ratio
- 217%
- SEC-reported price per share
- $29.41
- Number of holders
- 118
- Value change
- +$36,820,905
- Number of buys
- 70
- Number of sells
- 42
- Shares outstanding
- 101,961,572
Holder snapshot
7 signals
Open additional details 1 more signal available
Security identity
Names, identifiers, and filing context for this profile.
1 source field
Report period
Q3 2024
Institutions
118
Top holders
10
SYRE full security history
Ownership snapshot
Full 13F holder table
Newer quarter: Q3 2026
Spyre Therapeutics, Inc. SEC filings
Spyre Therapeutics, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 00773J202
Recent filing periods:
Ownership snapshot
Top reported holders of SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 par value (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
FMR LLC
Disclosed value leader
FMR LLC
Comparable rows
0/15
Latest evidence
30 Jun 2024
13F
Highest disclosed value: $176,512,680
15 rows are not safely comparable across share classes.
Showing 1-6 of 15 holder rows.
Quick read
FMR LLC has the largest disclosed position value at $176.51M.
0 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens FMR LLC's linked filing trail.
Disclosed position value
Top 5
FMR LLC
$176.51M
Fairmount Funds Management LLC
$94.47M
RTW INVESTMENTS, LP
$76.6M
PERCEPTIVE ADVISORS LLC
$71.26M
Venrock Adviser, LLC
$63.13M
Value bars compare disclosed positions; verify each figure against the linked filing evidence.
Detailed SEC evidence table Showing 1-6 of 15 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| FMR LLC |
13F
Company
|
—
denominator unverified
|
$176,512,680
7,507,983 shares
|
— | 30 Jun 2024 |
| Fairmount Funds Management LLC |
13F
Company
|
—
denominator unverified
|
$94,465,555
4,018,101 shares
|
— | 30 Jun 2024 |
| RTW INVESTMENTS, LP |
13F
Company
|
—
denominator unverified
|
$76,604,044
3,258,360 shares
|
— | 30 Jun 2024 |
| PERCEPTIVE ADVISORS LLC |
13F
Company
|
—
denominator unverified
|
$71,259,233
3,031,018 shares
|
— | 30 Jun 2024 |
| Venrock Adviser, LLC |
13F
Company
|
—
denominator unverified
|
$63,134,882
2,685,448 shares
|
— | 30 Jun 2024 |
| BRAIDWELL LP |
13F
Company
|
—
denominator unverified
|
$59,116,788
2,514,538 shares
|
— | 30 Jun 2024 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Institutional holders as of Q3 2024
Investor-level positions for this CUSIP, loaded as an interactive table.
Institutions
118
Shares
51,375,323
Rows available
118
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
Compare Q3 2024 vs Q2 2024 Across Filers
Q2 2024 holders
106
Q3 2024 holders
118
Holder diff
12
| Investor | Q2 2024 Shares | Q3 2024 Shares | Share Diff | Share Chg % | Q2 2024 value | Q3 2024 value | Value change | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend