Security key
00773J202
Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (SYRE)
CUSIP: 00773J202
Q3 2024 13F Holders as of 30 Sep 2024
- Type / Class
- Equity / Common Stock, $0.0001 Par Value Per Share
- Shares outstanding
- 86,389,920
- Total 13F shares
- 51,375,323
- Share change
- +732,563
- Total reported value
- $1,511,815,633
- Put/Call ratio
- 217%
- Price per share
- $29.41
- Number of holders
- 118
- Value change
- +$36,820,905
- Number of buys
- 70
- Number of sells
- 42
Report period
Q3 2024
Institutions
118
Top holders
10
SYRE full security history
Newer quarter: Q4 2024
Previous quarter: Q2 2024
Spyre Therapeutics, Inc. SEC filings
Spyre Therapeutics, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 00773J202
Recent filing periods:
Top shareholders of SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| FMR LLC |
13F
|
Company |
8.7%
|
7,507,983
|
$176,512,680 | — | 30 Jun 2024 | |
| Fairmount Funds Management LLC |
13F
|
Company |
4.7%
|
4,018,101
|
$94,465,555 | — | 30 Jun 2024 | |
| RTW INVESTMENTS, LP |
13F
|
Company |
3.8%
|
3,258,360
|
$76,604,044 | — | 30 Jun 2024 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
3.5%
|
3,031,018
|
$71,259,233 | — | 30 Jun 2024 | |
| Venrock Adviser, LLC |
13F
|
Company |
3.1%
|
2,685,448
|
$63,134,882 | — | 30 Jun 2024 | |
| BRAIDWELL LP |
13F
|
Company |
2.9%
|
2,514,538
|
$59,116,788 | — | 30 Jun 2024 | |
| BlackRock Finance, Inc. |
13F
|
Company |
2.8%
|
2,403,441
|
$56,504,899 | — | 30 Jun 2024 | |
| Commodore Capital LP |
13F
|
Company |
2.3%
|
1,988,084
|
$46,739,855 | — | 30 Jun 2024 | |
| VANGUARD GROUP INC |
13F
|
Company |
2.2%
|
1,911,566
|
$44,940,916 | — | 30 Jun 2024 | |
| Avoro Capital Advisors LLC |
13F
|
Company |
2.1%
|
1,839,138
|
$43,238,134 | — | 30 Jun 2024 | |
| Deep Track Capital, LP |
13F
|
Company |
2%
|
1,756,667
|
$41,299,241 | — | 30 Jun 2024 | |
| STATE STREET CORP |
13F
|
Company |
1.6%
|
1,409,659
|
$33,141,083 | — | 30 Jun 2024 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
1.3%
|
1,152,411
|
$27,093,183 | — | 30 Jun 2024 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
1%
|
893,083
|
$20,996,381 | — | 30 Jun 2024 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
0.92%
|
795,946
|
$18,712,691 | — | 30 Jun 2024 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.89%
|
765,834
|
$18,008,295 | — | 30 Jun 2024 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.86%
|
741,904
|
$17,442,163 | — | 30 Jun 2024 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.82%
|
707,586
|
$16,635,347 | — | 30 Jun 2024 | |
| Boxer Capital, LLC |
13F
|
Company |
0.81%
|
696,480
|
$16,374,245 | — | 30 Jun 2024 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.8%
|
687,080
|
$16,153,251 | — | 30 Jun 2024 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
0.78%
|
673,867
|
$15,916,739 | — | 30 Jun 2024 | |
| FARALLON CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.77%
|
666,000
|
$15,657,660 | — | 30 Jun 2024 | |
| Logos Global Management LP |
13F
|
Company |
0.67%
|
575,000
|
$13,518,250 | — | 30 Jun 2024 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
0.59%
|
513,420
|
$12,070,504 | — | 30 Jun 2024 | |
| Polar Capital Holdings Plc |
13F
|
Company |
0.58%
|
500,000
|
$11,755,000 | — | 30 Jun 2024 | |
| First Turn Management, LLC |
13F
|
Company |
0.54%
|
464,435
|
$10,918,867 | — | 30 Jun 2024 | |
| Darwin Global Management, Ltd. |
13F
|
Company |
0.52%
|
452,040
|
$10,265,828 | — | 30 Jun 2024 | |
| MORGAN STANLEY |
13F
|
Company |
0.47%
|
408,853
|
$9,612,133 | — | 30 Jun 2024 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.45%
|
386,617
|
$9,089,366 | — | 30 Jun 2024 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
0.36%
|
307,976
|
$7,242,000 | — | 30 Jun 2024 | |
| Blackstone Inc. |
13F
|
Company |
0.34%
|
292,995
|
$6,888,312 | — | 30 Jun 2024 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.32%
|
275,226
|
$6,470,563 | — | 30 Jun 2024 | |
| BALYASNY ASSET MANAGEMENT L.P. |
13F
|
Company |
0.32%
|
272,636
|
$6,409,672 | — | 30 Jun 2024 | |
| Woodline Partners LP |
13F
|
Company |
0.3%
|
262,616
|
$6,174,102 | — | 30 Jun 2024 | |
| Ghost Tree Capital, LLC |
13F
|
Company |
0.29%
|
250,237
|
$5,883,072 | — | 30 Jun 2024 | |
| Avidity Partners Management LP |
13F
|
Company |
0.23%
|
195,000
|
$4,584,450 | — | 30 Jun 2024 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.22%
|
191,169
|
$4,494,383 | — | 30 Jun 2024 | |
| Walleye Capital LLC |
13F
|
Company |
0.17%
|
150,820
|
$3,545,778 | — | 30 Jun 2024 | |
| STEMPOINT CAPITAL LP |
13F
|
Company |
0.17%
|
150,450
|
$3,537,080 | — | 30 Jun 2024 | |
| SOROS FUND MANAGEMENT LLC |
13F
|
Company |
0.17%
|
145,000
|
$3,408,950 | — | 30 Jun 2024 | |
| ARMISTICE CAPITAL, LLC |
13F
|
Company |
0.16%
|
136,000
|
$3,197,360 | — | 30 Jun 2024 | |
| GREAT POINT PARTNERS LLC |
13F
|
Company |
0.16%
|
134,612
|
$3,164,728 | — | 30 Jun 2024 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.14%
|
117,686
|
$2,766,798 | — | 30 Jun 2024 | |
| Nuveen Asset Management, LLC |
13F
|
Company |
0.14%
|
117,140
|
$2,753,962 | — | 30 Jun 2024 | |
| HighVista Strategies LLC |
13F
|
Company |
0.13%
|
113,550
|
$2,669,561 | — | 30 Jun 2024 | |
| SUVRETTA CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.12%
|
107,310
|
$2,522,858 | — | 30 Jun 2024 | |
| S.c.a. Candriam |
13F
|
Individual |
0.12%
|
105,000
|
$2,468,435 | — | 30 Jun 2024 | |
| Integral Health Asset Management, LLC |
13F
|
Company |
0.12%
|
100,000
|
$2,351,000 | — | 30 Jun 2024 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.11%
|
98,181
|
$2,308,235 | — | 30 Jun 2024 | |
| Jefferies Financial Group Inc. |
13F
|
Company |
0.11%
|
97,573
|
$2,293,941 | — | 30 Jun 2024 |
Institutional Holders of Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (SYRE) as of Q3 2024
As of 30 Sep 2024,
Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (SYRE) was held by
118 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
51,375,323 shares.
The largest 10 holders included
FMR LLC, Fairmount Funds Management LLC, RTW INVESTMENTS, LP, PERCEPTIVE ADVISORS LLC, VR Adviser, LLC, BlackRock, Inc., VANGUARD GROUP INC, BRAIDWELL LP, COMMODORE CAPITAL LP, and STATE STREET CORP.
This page lists
118
institutional shareholders reporting positions in this security
for the Q3 2024 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q3 2024 vs Q2 2024 Across Filers
Q2 2024 holders
106
Q3 2024 holders
118
Holder diff
12
| Investor | Q2 2024 Shares | Q3 2024 Shares | Share Diff | Share Chg % | Q2 2024 Value $ | Q3 2024 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.