Comparable stake leader
Opaleye Management Inc.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001655923.
Comparable stake leader
Opaleye Management Inc.
Disclosed value leader
Opaleye Management Inc.
Comparable rows
28/38
Latest evidence
26 Jun 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
28 of 38 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Opaleye Management Inc. |
13D/G
3/4/5
13F
10%+ Owner · Company
|
13%
|
$18,615,538
2,895,107 shares
|
+$1,766,565 | 26 Jun 2026 |
| AWM Investment Company, Inc. |
13D/G
13F
Company
|
9.9%
|
$14,118,234
2,172,036 shares
|
+$7,335,627 | 31 Dec 2025 |
| Solas Capital Management, LLC |
13F
13D/G
Company
|
8.7%
from 13D/G
|
$10,566,147
1,924,617 shares
|
— | 31 Mar 2026 |
| James E. Besser |
13D/G
BESSER JAMES E
|
6.2%
|
$5,176,527
1,003,203 shares
|
$0 | 15 Jan 2025 |
| Funicular Funds, LP |
13D/G
|
5.1%
|
$6,632,745
1,114,747 shares
|
+$324,483 | 11 Feb 2026 |
| Ikarian Capital, LLC |
13D/G
13F
Company
|
4.9%
|
$6,865,684
1,056,259 shares
|
+$574,548 | 31 Dec 2025 |
| MANCHESTER MANAGEMENT CO LLC |
13D/G
James E. Besser
|
4.9%
|
$6,493,918
1,076,935 shares
|
-$302,983 | 31 Mar 2026 |
| Cable Car Capital, LP |
13F
Company
|
6.4%
|
$7,589,041
1,382,339 shares
|
— | 31 Mar 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to buying over the last 12 months. Net value: +$4,313,859.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 336,657 | 0 | $2,055,979 | $0 | +$2,055,979 |
| 3-6 | 368,850 | 0 | $2,130,553 | $0 | +$2,130,553 |
| 6-9 | 0 | 0 | $0 | $0 | $0 |
| 9-12 | 42,778 | 27,778 | $377,330 | $250,002 | +$127,328 |
Reporting owners
Showing 1-11 of 11 reporting-owner rows connected to Alpha Cognition Inc.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Opaleye Management Inc. | 10%+ Owner | $18,451,553 | +$4,166,372 | +29% | Mixed | 25 Jun 2026 |
| Leonard Powell Mertz | Director | $1,737,053 | +$250,002 | +17% | Mixed | 14 Jan 2026 |
| Kenneth Anthony Cawkell | Director | $1,467,160 | Mixed | 14 Jan 2026 | ||
| Michael E. McFadden | Chief Executive Officer, Director | $1,330,491 | Mixed | 09 Jan 2026 | ||
| Lauren D'Angelo | Chief Operating Officer | $810,403 | +$20,160 | +2.6% | Filing P/S | 19 May 2026 |
| Phillip Joseph Mertz | Director | $274,709 | -$250,002 | -48% | Mixed | 14 Jan 2026 |
| Robert James Wills | Director | $144,566 | +$127,328 | +739% | Mixed | 14 Jan 2026 |
| Huy du Henry | VP Finance and Accounting | $133,763 | Mixed | 09 Jan 2026 | ||
| Rajeev Kumar Baskhi | Director | $124,045 | Mixed | 14 Jan 2026 | ||
| Bethany Sensenig | Director | $32,887 | Mixed | 16 Apr 2026 | ||
| John Prentiss Havens | Director | Mixed | 25 Feb 2025 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 5.74% | $975,209 | $6.40 | 152,336 | 2,805,107 | 26 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.01% | $1,280 | $6.50 | 197 | 2,652,771 | 25 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.17% | $27,253 | $5.99 | 4,550 | 2,652,574 | 15 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.01% | $1,619 | $5.93 | 273 | 2,648,024 | 12 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.11% | $16,901 | $5.91 | 2,862 | 2,647,751 | 11 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.22% | $35,157 | $5.99 | 5,872 | 2,644,889 | 10 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.95% | $148,534 | $5.98 | 24,856 | 2,639,017 | 09 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.39% | $58,596 | $5.83 | 10,054 | 2,614,161 | 05 Jun 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 2.79% | $416,397 | $5.90 | 70,577 | 2,604,107 | 29 May 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.08% | $11,664 | $5.83 | 2,000 | 2,533,530 | 28 May 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.05% | $6,653 | $5.73 | 1,161 | 2,531,530 | 27 May 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.63% | $90,886 | $5.70 | 15,945 | 2,530,369 | 21 May 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.34% | $49,659 | $5.89 | 8,431 | 2,514,424 | 20 May 2026 | By Opaleye, L.P. |
| Lauren D'Angelo | ACOG | Common Shares | Purchase | 2.55% | $20,160 | $5.76 | 3,500 | 140,695 | 19 May 2026 | Direct |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.7% | $99,023 | $5.69 | 17,395 | 2,505,993 | 18 May 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.67% | $96,986 | $5.83 | 16,648 | 2,488,598 | 15 May 2026 | By Opaleye, L.P. |
| Bethany Sensenig | ACOG | Common Shares | Award | 5,489 | 5,489 | 16 Apr 2026 | Direct | |||
| Bethany Sensenig | ACOG | Common Share Options | Award | 6,991 | 6,991 | 16 Apr 2026 | Direct | |||
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.07% | $9,227 | $4.99 | 1,850 | 2,471,850 | 30 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.41% | $50,792 | $5.08 | 10,000 | 2,470,000 | 27 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.3% | $38,675 | $5.28 | 7,319 | 2,460,000 | 26 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.35% | $46,579 | $5.43 | 8,581 | 2,452,681 | 25 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.17% | $23,377 | $5.59 | 4,182 | 2,444,100 | 24 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.09% | $11,950 | $5.71 | 2,094 | 2,439,918 | 19 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.1% | $14,263 | $5.75 | 2,481 | 2,437,824 | 18 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.05% | $7,696 | $5.78 | 1,331 | 2,435,343 | 16 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.3% | $42,286 | $5.75 | 7,358 | 2,434,012 | 13 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.24% | $33,416 | $5.85 | 5,708 | 2,426,654 | 12 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.09% | $12,742 | $5.85 | 2,179 | 2,420,946 | 09 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.08% | $11,018 | $5.80 | 1,900 | 2,418,767 | 06 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 5.88% | $28,988 | $5.80 | 5,000 | 90,000 | 05 Mar 2026 | By Managed Account |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 1.77% | $243,633 | $5.80 | 42,023 | 2,416,867 | 05 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.84% | $115,001 | $5.81 | 19,795 | 2,374,844 | 04 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 6.25% | $28,751 | $5.75 | 5,000 | 85,000 | 03 Mar 2026 | By Managed Account |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 2.01% | $266,873 | $5.75 | 46,411 | 2,355,049 | 03 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.87% | $116,000 | $5.80 | 20,000 | 2,308,638 | 02 Mar 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.16% | $21,797 | $5.99 | 3,638 | 2,288,638 | 27 Feb 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.03% | $3,531 | $5.98 | 590 | 2,285,000 | 26 Feb 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 6.67% | $29,002 | $5.80 | 5,000 | 80,000 | 24 Feb 2026 | By Managed Account |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 2.4% | $310,849 | $5.80 | 53,591 | 2,284,410 | 24 Feb 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 5.9% | $24,636 | $5.89 | 4,181 | 75,000 | 23 Feb 2026 | By Managed Account |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 4.49% | $564,594 | $5.89 | 95,819 | 2,230,819 | 23 Feb 2026 | By Opaleye, L.P. |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 4.15% | $16,466 | $5.84 | 2,819 | 70,819 | 20 Feb 2026 | By Managed Account |
| Opaleye Management Inc. | ACOG | Common Stock, no par value | Purchase | 0.47% | $58,411 | $5.84 | 10,000 | 2,135,000 | 20 Feb 2026 | By Opaleye, L.P. |
| Phillip Joseph Mertz | ACOG | Common Shares | Award | 32.2% | 7,241 | 29,703 | 14 Jan 2026 | Direct | ||
| Phillip Joseph Mertz | ACOG | Common Share Options | Award | 8,437 | 8,437 | 14 Jan 2026 | Direct | |||
| Robert James Wills | ACOG | Common Shares | Award | 48.3% | 7,241 | 22,241 | 14 Jan 2026 | Direct | ||
| Robert James Wills | ACOG | Common Share Options | Award | 8,437 | 8,437 | 14 Jan 2026 | Direct | |||
| Leonard Powell Mertz | ACOG | Common Shares | Award | 5.23% | 7,241 | 145,736 | 14 Jan 2026 | Direct | ||
| Leonard Powell Mertz | ACOG | Common Share Options | Award | 8,437 | 8,437 | 14 Jan 2026 | Direct |