Insider Transactions Reported by 22 Insiders of CODEXIS, INC.

Symbol: CDXS on Nasdaq
Location: Redwood City, CA

Key facts

CDXS - CODEXIS, INC. has 22 insiders with reported activity on this page.
Net insider value flow over the last year: +$5,349,675.
Recent transaction rows are available for direct filing-level review.

Change

Buy value: $8,548,198; sell value: $3,198,522.
Net share flow: +1,946,455.

Research use

This page gives a plain-language issuer insider context before you inspect transaction-level evidence.
Use the filing links below to verify timestamps, codes, and ownership impacts directly from SEC forms.

Evidence

Filed on Form 4

Issuer insider activity is sourced from SEC Forms 3, 4, and 5.

See Original Filing

Insider trading overview

Last 12 months

Net insider flow leans to buying over the last 12 months. Net value: +$5,349,675.

Buys

$8,548,198

Shares: 3,760,000

Insiders: 1

Sells

$3,198,523

Shares: 1,813,545

Insiders: 6

Net

+$5,349,675

Shares: +1,946,455

Insiders: -5

Window (months)	Buy shares	Sell shares	Buy $	Sell $	Net $
0-3	0	5,862	$0	$6,641	-$6,641
3-6	0	529,170	$0	$899,055	-$899,055
6-9	890,000	1,278,513	$1,724,108	$2,292,827	-$568,719
9-12	2,870,000	0	$6,824,090	$0	+$6,824,090

CODEXIS, INC. executives and other stock owners filed with the SEC include:

Name	Relationship	Holdings Value	Past Year Net Change	Change %	Valuation	Report Date
Opaleye Management Inc.	10%+ Owner	$16,900,093	+$5,425,230	+47%	Filing P/S	26 Nov 2025
John J. Nicols	Director	$1,652,912			Mixed	17 Apr 2023
Stephen G. Dilly	Director	$1,343,085			Mixed	11 Nov 2025
Kevin Norrett	Chief Operating Officer	$761,265			Mixed	05 Feb 2025
David V Smith	Director	$489,572			Mixed	10 Jun 2025
Byron L. Dorgan	Director	$471,398			Mixed	11 Jun 2024
Bernard J. Kelley	Director	$434,617			Mixed	10 Aug 2021
Sriram Ryali	Chief Financial Officer	$370,638			Mixed	01 Jan 2024
PARKER H STEWART	Director	$361,829			Mixed	10 Jun 2025
Rahul Singhvi	Director	$345,371			Mixed	10 Jun 2025
Alison Moore	President and CEO, Director	$327,436	-$20,630	-5.9%	Filing P/S	23 Feb 2026
Esther Martinborough	Director	$325,170			Mixed	10 Jun 2025
Cynthia Collins	Director	$282,635			Mixed	10 Jun 2025
Margaret Nell Fitzgerald	Chief Legal and Compliance Officer	$282,041			Mixed	01 Jan 2024
Dennis P. Wolf	Director	$217,124	-$13,988	-6.1%	Filing P/S	21 Nov 2025
Christos Richards	Director	$214,535			Mixed	10 Jun 2025
Raymond de Vre	Director	$152,103	-$2,459	-1.6%	Filing P/S	11 Nov 2025
Stefan Lutz	Chief Scientific Officer	$147,753	-$17,848	-11%	Filing P/S	23 Feb 2026
Jennifer Aaker	Director	$139,599			Mixed	13 Jun 2023
Patrick Y. Yang	Director	$113,400			Mixed	14 Jun 2022
Georgia Erbez	Chief Financial Officer and Chief Business Officer	$87,327	-$20,630	-19%	Filing P/S	23 Feb 2026
Dean Ross Taylor Jr.	Advisor	$81,287			Mixed	07 Feb 2023

Top shareholders of CODEXIS, INC. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Opaleye Management Inc.	3/4/5 13D/G 13F	10%+ Owner · Company	7.5% from 13D/G	10,134,989	$16,900,093	+$5,425,230	26 Nov 2025	3/4/5 13D/G 13F
Aberdeen Group plc	13F 13D/G	Company	8.8% from 13D/G	8,680,368	$14,149,000	—	31 Mar 2026	13F 13D/G
BlackRock, Inc.	13D/G 13F	Company	7.2%	5,979,480	$13,752,804	$0	31 Mar 2025	13D/G 13F
INTEGRATED CORE STRATEGIES (US) LLC	13D/G	—	5.2%	4,734,627	$7,812,135	$0	09 Apr 2026	13D/G
Nantahala Capital Management, LLC	13D/G 13F	Company	4.3%	2,967,808	$6,825,958	$0	30 Sep 2024	13D/G 13F
MILLENNIUM MANAGEMENT LLC	13F	Company	4.4%	3,998,130	$6,516,952	—	31 Mar 2026	13F
Telemark Asset Management, LLC	13F	Company	4.2%	3,846,411	$6,269,650	—	31 Mar 2026	13F
VANGUARD CAPITAL MANAGEMENT LLC	13F	Company	4%	3,668,507	$5,979,666	—	31 Mar 2026	13F
AMERIPRISE FINANCIAL INC	13F	Company	3.7%	3,400,496	$5,542,809	—	31 Mar 2026	13F
Laurence W. Lytton	13D/G	LYTTON LAURENCE W	5%	4,532,069	$5,347,841	$0	06 Mar 2026	13D/G
UBS Group AG	13F	Company	2.4%	2,183,775	$3,559,554	—	31 Mar 2026	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	2.1%	1,885,353	$3,073,787	—	31 Mar 2026	13F
STATE STREET CORP	13F	Company	1.8%	1,666,954	$2,717,135	—	31 Mar 2026	13F
JACOBS LEVY EQUITY MANAGEMENT, INC	13F	Company	1.2%	1,088,027	$1,773,484	—	31 Mar 2026	13F
John J. Nicols	3/4/5	Director	— mixed-class rows	926,821 mixed-class rows	$1,652,912	—	17 Apr 2023	3/4/5
D. E. Shaw & Co., Inc.	13F	Company	1.1%	979,847	$1,597,151	—	31 Mar 2026	13F
JANE STREET GROUP, LLC	13F	Company	1%	919,964	$1,499,541	—	31 Mar 2026	13F
VANGUARD PORTFOLIO MANAGEMENT LLC	13F	Company	0.97%	879,339	$1,433,323	—	31 Mar 2026	13F
FMR LLC	13D/G 13F	Company	0.6%	584,367	$1,425,855	$0	30 Sep 2025	13D/G 13F
Private Advisor Group, LLC	13F	Company	0.93%	847,001	$1,380,612	—	31 Mar 2026	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.91%	824,870	$1,344,537	—	31 Mar 2026	13F
Stephen G. Dilly	3/4/5	Director	— mixed-class rows	1,259,553 mixed-class rows	$1,343,085	—	11 Nov 2025	3/4/5
Assenagon Asset Management S.A.	13F	Company	0.83%	751,170	$1,224,407	—	31 Mar 2026	13F
FRANKLIN RESOURCES INC	13F	Company	0.76%	688,210	$1,121,782	—	31 Mar 2026	13F
NORTHERN TRUST CORP	13F	Company	0.72%	657,139	$1,071,136	—	31 Mar 2026	13F
AQR CAPITAL MANAGEMENT LLC	13F	Company	0.67%	608,601	$992,021	—	31 Mar 2026	13F
Post Resch Tallon Group Inc.	13F	Company	0.63%	571,478	$974,941	—	31 Mar 2026	13F
VANGUARD FIDUCIARY TRUST CO	13F	Company	0.61%	551,008	$898,143	—	31 Mar 2026	13F
TUDOR INVESTMENT CORP ET AL	13F	Company	0.59%	537,833	$876,668	—	31 Mar 2026	13F
PERKINS CAPITAL MANAGEMENT INC	13F	Company	0.58%	527,500	$859,825	—	31 Mar 2026	13F
MORGAN STANLEY	13F	Company	0.52%	472,841	$770,731	—	31 Mar 2026	13F
Kevin Norrett	3/4/5	Chief Operating Officer	— mixed-class rows	338,577 mixed-class rows	$761,265	—	05 Feb 2025	3/4/5
Stonepine Capital Management, LLC	13F	Company	0.46%	417,994	$681,330	—	31 Mar 2026	13F
Nuveen, LLC	13F	Company	0.4%	367,443	$598,932	—	31 Mar 2026	13F
Diametric Capital, LP	13F	Company	0.4%	359,268	$585,606	—	31 Mar 2026	13F
David V Smith	3/4/5	Director	0.21%	194,275	$489,572	—	10 Jun 2025	3/4/5
Byron L. Dorgan	3/4/5	Director	— class O/S missing	223,581	$471,398	—	11 Jun 2024	3/4/5
CITADEL ADVISORS LLC	13F	Company	0.32%	287,595	$468,780	—	31 Mar 2026	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.31%	284,636	$463,390	—	31 Mar 2026	13F
LAZARD ASSET MANAGEMENT LLC	13F	Company	0.31%	282,380	$460,279	—	31 Mar 2026	13F
Potomac Capital Management, Inc.	13F	Company	0.3%	274,200	$446,946	—	31 Mar 2026	13F
Bernard J. Kelley	3/4/5	Director	— class O/S missing	206,136	$434,617	—	10 Aug 2021	3/4/5
PLATINUM INVESTMENT MANAGEMENT LTD	13F	Company	0.29%	264,464	$431,076	—	31 Mar 2026	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.27%	242,211	$394,804	—	31 Mar 2026	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.27%	241,955	$394,387	—	31 Mar 2026	13F
Sriram Ryali	3/4/5	Chief Financial Officer	— mixed-class rows	489,916 mixed-class rows	$370,638	—	01 Jan 2024	3/4/5
PARKER H STEWART	3/4/5	Director	0.16%	143,583	$361,829	—	10 Jun 2025	3/4/5
ROYAL BANK OF CANADA	13F	Company	0.24%	215,301	$351,000	—	31 Mar 2026	13F
Rahul Singhvi	3/4/5	Director	0.15%	137,052	$345,371	—	10 Jun 2025	3/4/5
Bank of New York Mellon Corp	13F	Company	0.23%	209,645	$341,720	—	31 Mar 2026	13F

Recent Insider Transactions by Companies or Individuals for CODEXIS, INC.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider	Symbol	Class	Transaction	%	Value $	* Price $	Shares	Shares Owned	Date	Ownership
Stefan Lutz	CDXS	Common Stock	Sale	-4.3%	$6,641	$1.13	-5,862	130,421	24 Feb 2026	Direct
Stefan Lutz	CDXS	Stock Option (Right to Buy)	Award				316,100	316,100	23 Feb 2026	Direct
Alison Moore	CDXS	Stock Option (Right to Buy)	Award				993,000	993,000	23 Feb 2026	Direct
Georgia Erbez	CDXS	Stock Option (Right to Buy)	Award				316,100	316,100	23 Feb 2026	Direct
Stefan Lutz	CDXS	Common Stock	Sale	-1.8%	$3,257	$1.31	-2,492	136,283	06 Feb 2026	Direct
Georgia Erbez	CDXS	Common Stock	Sale	-5.42%	$5,001	$1.31	-3,826	66,810	06 Feb 2026	Direct
Alison Moore	CDXS	Common Stock	Sale	-1.5%	$5,001	$1.31	-3,826	250,506	06 Feb 2026	Direct
Stefan Lutz	CDXS	Common Stock	Sale	-3.27%	$7,950	$1.70	-4,685	138,775	07 Jan 2026	Direct
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-4.53%	$14,229	$1.67	-8,533	179,989	01 Dec 2025	By Managed Account
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-2.4%	$408,538	$1.67	-245,000	9,955,000	01 Dec 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-1.3%	$4,358	$1.75	-2,490	188,522	28 Nov 2025	By Managed Account
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-1.02%	$183,750	$1.75	-105,000	10,200,000	28 Nov 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-2.55%	$8,706	$1.74	-5,000	191,012	26 Nov 2025	By Managed Account
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-1.42%	$258,266	$1.74	-148,318	10,305,000	26 Nov 2025	By Opaleye, L.P.
Dennis P. Wolf	CDXS	Common Stock	Sale	-6.05%	$13,988	$1.56	-8,952	138,951	21 Nov 2025	Direct
Alison Moore	CDXS	Common Stock	Award	50.2%			85,000	254,332	13 Nov 2025	Direct
Alison Moore	CDXS	Stock Option (Right to Buy)	Award				500,000	500,000	13 Nov 2025	Direct
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-1.55%	$323,730	$1.96	-165,000	10,453,318	12 Nov 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-12.3%	$53,194	$1.94	-27,459	196,012	12 Nov 2025	By Managed Account
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	9.15%	$1,724,108	$1.94	890,000	10,618,318	12 Nov 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-5.58%	$23,772	$1.80	-13,211	223,461	11 Nov 2025	By Managed Account
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-4.44%	$962,679	$1.80	-535,000	11,508,318	11 Nov 2025	By Opaleye, L.P.
Raymond de Vre	CDXS	Common Stock	Sale	-1.59%	$2,459	$1.74	-1,413	87,416	11 Nov 2025	Direct
Stephen G. Dilly	CDXS	Common Stock	Award	7.38%			50,000	727,053	11 Nov 2025	Direct
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-1.38%	$5,756	$1.73	-3,318	236,682	10 Nov 2025	By Managed Account
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-1.67%	$355,614	$1.73	-205,000	12,043,318	10 Nov 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-4%	$16,968	$1.70	-10,000	240,000	07 Nov 2025	By Managed Account
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Sale	-2.36%	$503,410	$1.70	-296,682	12,248,318	07 Nov 2025	By Opaleye, L.P.
Alison Moore	CDXS	Common Stock	Sale	-3.55%	$15,629	$2.51	-6,239	169,332	13 Oct 2025	Direct
Georgia Erbez	CDXS	Common Stock	Sale	-8.12%	$15,629	$2.50	-6,239	70,636	13 Oct 2025	Direct
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.01%	$2,211	$2.84	780	12,545,000	04 Aug 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.68%	$225,710	$2.68	84,220	12,544,220	31 Jul 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.01%	$4,411	$2.80	1,578	12,460,000	30 Jul 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.07%	$23,750	$2.82	8,422	12,458,422	29 Jul 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.81%	$282,000	$2.82	100,000	12,450,000	18 Jul 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.82%	$239,000	$2.39	100,000	12,350,000	27 Jun 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.42%	$114,012	$2.24	50,898	12,250,000	16 Jun 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.82%	$220,997	$2.23	99,102	12,199,102	13 Jun 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.83%	$225,000	$2.25	100,000	12,100,000	12 Jun 2025	By Opaleye, L.P.
Dennis P. Wolf	CDXS	Common Stock	Award	38.3%			40,983	147,903	10 Jun 2025	Direct
David V Smith	CDXS	Common Stock	Award	63.3%			40,983	105,705	10 Jun 2025	Direct
Rahul Singhvi	CDXS	Common Stock	Award	42.7%			40,983	137,052	10 Jun 2025	Direct
Christos Richards	CDXS	Common Stock	Award	92.8%			40,983	85,133	10 Jun 2025	Direct
Parker H Stewart	CDXS	Common Stock	Award	39.9%			40,983	143,583	10 Jun 2025	Direct
Esther Martinborough	CDXS	Common Stock	Award	46.5%			40,983	129,036	10 Jun 2025	Direct
Raymond de Vre	CDXS	Common Stock	Award	85.7%			40,983	88,829	10 Jun 2025	Direct
Cynthia Collins	CDXS	Common Stock	Award	57.6%			40,983	112,157	10 Jun 2025	Direct
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	0.04%	$11,800	$2.36	5,000	12,000,000	28 May 2025	By Opaleye, L.P.
Opaleye Management Inc.	CDXS	Common Stock, par value $0.001 per share	Purchase	24%	$5,475,200	$2.36	2,320,000	11,995,000	23 May 2025	By Opaleye, L.P.

* An asterisk sign (*) next to the price indicates that the price is likely invalid.