Insider Transactions Reported by 18 Insiders of Caris Life Sciences, Inc.

Symbol: CAI on Nasdaq
Location: Irving, TX

Key facts

CAI - Caris Life Sciences, Inc. has 18 insiders with reported activity on this page.
Net insider value flow over the last year: -$1,042,702.
Recent transaction rows are available for direct filing-level review.

Change

Buy value: $611,759; sell value: $1,654,461.
Net share flow: -26,616.

Research use

This page gives a plain-language issuer insider context before you inspect transaction-level evidence.
Use the filing links below to verify timestamps, codes, and ownership impacts directly from SEC forms.

Evidence

Filed on Form 4

Issuer insider activity is sourced from SEC Forms 3, 4, and 5.

See Original Filing

Insider trading overview

Last 12 months

Net insider flow leans to selling over the last 12 months. Net value: -$1,042,702.

Buys

$611,759

Shares: 35,634

Insiders: 3

Sells

$1,654,461

Shares: 62,250

Insiders: 1

Net

-$1,042,702

Shares: -26,616

Insiders: 2

Window (months)	Buy shares	Sell shares	Buy $	Sell $	Net $
0-3	31,050	0	$501,426	$0	+$501,426
3-6	0	62,250	$0	$1,654,461	-$1,654,461
6-9	4,584	0	$110,333	$0	+$110,333
9-12	0	0	$0	$0	$0

Caris Life Sciences, Inc. executives and other stock owners filed with the SEC include:

Name	Relationship	Holdings Value	Past Year Net Change	Change %	Valuation	Report Date
David D. Halbert	Founder, Chairman, and Chief Executive Officer, Director, 10%+ Owner	$2,209,959,685			Median	15 May 2026
Peter M. Castleman	Director	$275,313,217			Mixed	26 Feb 2026
Jon Halbert	Director	$35,504,537			Mixed	26 Feb 2026
George Poste	Director	$14,706,366			Mixed	11 Aug 2025
Brian J. Brille	Vice Chairman and Executive Vice President, Director	$13,057,817			Median	15 May 2026
David Baxley Spetzler	President	$9,477,884	+$9,540	+0.1%	Median	15 May 2026
J. Russel Denton	Senior Vice President, General Counsel, and Secretary	$3,409,697	+$100,793	+3%	Median	15 May 2026
Luke Thomas Power	Senior Vice President, Chief Financial Officer, and Chief Accounting Officer	$2,749,425	-$1,654,461	-38%	Median	15 May 2026
Phillips T. Danny	Director	$2,404,552			Mixed	26 Feb 2026
Jeff L. Vacirca	Director	$802,136	+$501,426	+167%	Filing P/S	11 May 2026
David Paul Fredrickson	Director	$373,537			Mixed	26 Feb 2026
Lloyd Minor	Director	$373,537			Mixed	26 Feb 2026
Joseph E. Gilliam	Director				Mixed	17 Jun 2025
Jonathan Kenneth Charles Knowles	Director				Mixed	17 Jun 2025
Laura I. Johansen	Director				Mixed	17 Jun 2025
J H Whitney VI L P	10%+ Owner				Mixed	20 Jun 2025
TSSP Sub-Fund HoldCo LLC	Former 10% Owner				Mixed	20 Jun 2025
ADAPT I Ltd.	10%+ Owner				Mixed	20 Jun 2025

Top shareholders of Caris Life Sciences, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
David D. Halbert	13D/G 3/4/5	Founder, Chairman, and Chief Executive Officer, Director, 10%+ Owner	44%	124,906,296	$3,311,265,907	$0	30 Jun 2025	13D/G 3/4/5
FMR LLC	13F 13D/G	Company	11% from 13D/G	30,785,585	$550,446,260	—	31 Mar 2026	13F 13D/G
J H Whitney VI L P	13D/G 3/4/5	10%+ Owner	6.5%	18,256,615	$329,531,901	-$36,100,000	31 Mar 2026	13D/G 3/4/5
J. H. Whitney Equity Partners VI, LLC	13F	Company	6.5%	18,256,615	$326,428,276	—	31 Mar 2026	13F
Peter M. Castleman	3/4/5	Director	3.7%	10,395,044	$275,313,217	—	26 Feb 2026	3/4/5
TSSP Sub-Fund HoldCo LLC	13D/G 3/4/5	Alan Waxman · Former 10% Owner	5.1%	14,385,399	$259,656,452	-$90,250,000	31 Mar 2026	13D/G 3/4/5
Sixth Street Partners Management Company, L.P.	13F	Company	5.1%	14,385,399	$257,210,934	—	31 Mar 2026	13F
COATUE MANAGEMENT LLC	13F	Company	3.5%	9,819,992	$175,581,457	—	31 Mar 2026	13F
BRAIDWELL LP	13F	Company	2.8%	8,009,447	$143,208,912	—	31 Mar 2026	13F
PointState Capital LP	13F	Company	2.6%	7,360,446	$131,604,774	—	31 Mar 2026	13F
T. Rowe Price Investment Management, Inc.	13F	Company	2%	5,588,257	$99,919,000	—	31 Mar 2026	13F
BlackRock, Inc.	13F	Company	1.7%	4,857,112	$86,845,162	—	31 Mar 2026	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	1.5%	4,371,771	$78,168,000	—	31 Mar 2026	13F
VANGUARD PORTFOLIO MANAGEMENT LLC	13F	Company	1.3%	3,758,462	$67,201,301	—	31 Mar 2026	13F
Neuberger Berman Group LLC	13F	Company	1.3%	3,590,586	$64,199,677	—	31 Mar 2026	13F
VANGUARD CAPITAL MANAGEMENT LLC	13F	Company	1.2%	3,329,021	$59,522,895	—	31 Mar 2026	13F
JPMORGAN CHASE & CO	13F	Company	1.2%	3,460,215	$58,304,631	—	31 Mar 2026	13F
ORBIMED ADVISORS LLC	13F	Company	1%	2,806,811	$50,185,781	—	31 Mar 2026	13F
UBS Group AG	13F	Company	0.97%	2,745,811	$49,095,101	—	31 Mar 2026	13F
LOS ANGELES CAPITAL MANAGEMENT LLC	13F	Company	0.81%	2,289,602	$40,938,083	—	31 Mar 2026	13F
Jon Halbert	3/4/5	Director	0.49%	1,368,621	$35,504,537	—	26 Feb 2026	3/4/5
Duquesne Family Office LLC	13F	Company	0.67%	1,894,450	$33,873,000	—	31 Mar 2026	13F
BNP PARIBAS FINANCIAL MARKETS	13F	Company	0.57%	1,614,286	$28,863,434	—	31 Mar 2026	13F
Clearbridge Investments, LLC	13F	Company	0.55%	1,551,774	$27,745,714	—	31 Mar 2026	13F
FIL Ltd	13F	Company	0.55%	1,546,091	$27,644,107	—	31 Mar 2026	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.54%	1,527,756	$27,316,277	—	31 Mar 2026	13F
CANADA PENSION PLAN INVESTMENT BOARD	13F	Company	0.47%	1,322,752	$23,650,806	—	31 Mar 2026	13F
Invesco Ltd.	13F	Company	0.43%	1,222,278	$21,854,331	—	31 Mar 2026	13F
Champlain Investment Partners, LLC	13F	Company	0.43%	1,207,963	$21,598,378	—	31 Mar 2026	13F
Capital World Investors	13F	Company	0.42%	1,180,173	$21,101,493	—	31 Mar 2026	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	0.41%	1,149,133	$20,546,499	—	31 Mar 2026	13F
MORGAN STANLEY	13F	Company	0.38%	1,079,417	$19,299,976	—	31 Mar 2026	13F
STATE STREET CORP	13F	Company	0.35%	984,953	$17,610,960	—	31 Mar 2026	13F
Point72 Asset Management, L.P.	13F	Company	0.33%	918,331	$16,419,758	—	31 Mar 2026	13F
George Poste	3/4/5	Director	0.19%	527,831	$14,706,366	—	11 Aug 2025	3/4/5
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.28%	778,532	$13,920,151	—	31 Mar 2026	13F
Gotham Asset Management, LLC	13F	Company	0.26%	744,426	$13,310,337	—	31 Mar 2026	13F
Brian J. Brille	3/4/5	Vice Chairman and Executive Vice President, Director	0.26%	730,303	$13,057,817	—	15 May 2026	3/4/5
Woodline Partners LP	13F	Company	0.26%	723,163	$12,930,154	—	31 Mar 2026	13F
TD ASSET MANAGEMENT INC	13F	Company	0.24%	670,388	$11,986,537	—	31 Mar 2026	13F
Nuveen, LLC	13F	Company	0.24%	663,578	$11,864,775	—	31 Mar 2026	13F
ZEVENBERGEN CAPITAL INVESTMENTS LLC	13F	Company	0.22%	610,233	$10,910,966	—	31 Mar 2026	13F
SEI INVESTMENTS CO	13F	Company	0.21%	598,712	$10,704,973	—	31 Mar 2026	13F
Rock Springs Capital Management LP	13F	Company	0.2%	563,000	$10,066,440	—	31 Mar 2026	13F
David Baxley Spetzler	3/4/5	President	0.19%	530,083	$9,477,884	+$9,540	15 May 2026	3/4/5
BANK OF AMERICA CORP /DE/	13F	Company	0.19%	523,268	$9,356,031	—	31 Mar 2026	13F
Trexquant Investment LP	13F	Company	0.17%	490,536	$8,770,784	—	31 Mar 2026	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	0.16%	449,900	$8,044,212	—	31 Mar 2026	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.15%	410,340	$7,336,880	—	31 Mar 2026	13F
AMERIPRISE FINANCIAL INC	13F	Company	0.14%	408,079	$7,296,452	—	31 Mar 2026	13F

Recent Insider Transactions by Companies or Individuals for Caris Life Sciences, Inc.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider	Symbol	Class	Transaction	%	Value $	* Price $	Shares	Shares Owned	Date	Ownership
J. Russel Denton	CAI	Common Stock	Tax liability	-3.22%			-6,047	181,515	15 May 2026	Direct
Luke Thomas Power	CAI	Common Stock	Tax liability	-5.97%			-9,771	153,771	15 May 2026	Direct
David Baxley Spetzler	CAI	Common Stock	Tax liability	-2.55%			-13,856	530,083	15 May 2026	Direct
Brian J. Brille	CAI	Common Stock	Tax liability	-5.73%			-13,987	230,303	15 May 2026	Direct
David D. Halbert	CAI	Common Stock	Tax liability	-1.56%			-40,712	2,574,533	15 May 2026	Direct
Jeff L. Vacirca	CAI	Common Stock	Purchase	166.8%	$501,426	$16.15	31,050	49,671	11 May 2026	Direct
J. Russel Denton	CAI	Common Stock	Award	51.8%			63,971	187,562	06 Mar 2026	Direct
David Baxley Spetzler	CAI	Common Stock	Award	18%			83,162	543,939	06 Mar 2026	Direct
Brian J. Brille	CAI	Common Stock	Award	51.6%			83,162	244,290	06 Mar 2026	Direct
Luke Thomas Power	CAI	Common Stock	Award	64.2%			63,971	163,542	06 Mar 2026	Direct
David D. Halbert	CAI	Common Stock	Award	14%			320,112	2,615,245	06 Mar 2026	Direct
Lloyd Minor	CAI	Common Stock	Award	15.4%			2,492	18,621	26 Feb 2026	Direct
Jeff L. Vacirca	CAI	Common Stock	Award	15.4%			2,492	18,621	26 Feb 2026	Direct
David Paul Fredrickson	CAI	Common Stock	Award	15.4%			2,492	18,621	26 Feb 2026	Direct
Jon Halbert	CAI	Common Stock	Award	2.15%			2,492	118,621	26 Feb 2026	Direct
Phillips T. Danny	CAI	Common Stock	Award	3.22%			3,739	119,868	26 Feb 2026	Direct
Peter M. Castleman	CAI	Common Stock	Award	29.6%			5,509	24,138	26 Feb 2026	Direct
Peter M. Castleman		Common Stock	Options Exercise	15.5%			2,500	18,629	09 Jan 2026	Direct
Peter M. Castleman		Stock Option	Options Exercise	-100%			-2,500	0	09 Jan 2026	Direct
Luke Thomas Power		Common Stock	Sale	-38.5%	$1,654,461	$26.58	-62,250	99,571	11 Dec 2025	Direct
Luke Thomas Power		Common Stock	Options Exercise	62.5%			62,250	161,821	11 Dec 2025	Direct
Luke Thomas Power		Stock Option	Options Exercise	-100%			-62,250	0	11 Dec 2025	Direct
Brian J. Brille		Common Stock	Gift	-0.4%			-650	161,128	11 Dec 2025	Direct
Brian J. Brille		Common Stock	Gift	-0.4%			-650	161,778	10 Dec 2025	Direct
David Baxley Spetzler		Common Stock	Purchase	0.09%	$9,540	$23.85	400	460,777	07 Nov 2025	Direct
J. Russel Denton		Common Stock	Purchase	83.7%	$100,793	$24.09	4,184	9,184	07 Nov 2025	By Trust
Phillips T. Danny		Common Stock	Options Exercise	620%			100,000	116,129	11 Sep 2025	Direct
Phillips T. Danny		Stock Option	Options Exercise	-100%			-100,000	0	11 Sep 2025	Direct
George Poste		Common Stock	Tax liability	-38.8%			-139,517	220,237	11 Aug 2025	Direct
George Poste		Common Stock	Options Exercise	53.2%			125,000	359,754	11 Aug 2025	Direct
George Poste		Stock Option	Options Exercise				125,000	0	11 Aug 2025	Direct
David Baxley Spetzler		Common Stock	Tax liability	-12.1%			-63,509	460,377	11 Aug 2025	Direct
David D. Halbert		Common Stock	Tax liability	-5.82%			-141,956	2,295,133	11 Aug 2025	Direct
David Baxley Spetzler		Common Stock	Tax liability	-6.23%			-34,782	523,886	20 Jun 2025	Direct
David Baxley Spetzler		Common Stock	Options Exercise	15.5%			75,000	558,668	20 Jun 2025	Direct
David Baxley Spetzler		Stock Option	Options Exercise	-100%			-75,000	0	20 Jun 2025	Direct
Jon Halbert		Common Stock	Conversion of derivative security				1,250,000	1,250,000	20 Jun 2025	By Ke'Ohana Ventures, LLC
Jon Halbert		Series A Preferred Stock	Conversion of derivative security	-100%			-5,000,000	0	20 Jun 2025	By Ke'Ohana Ventures, LLC
J H Whitney VI L P		Common Stock	Conversion of derivative security	161.7%			12,516,834	20,256,615	20 Jun 2025	See Footnote
J H Whitney VI L P		Series A Preferred Stock	Conversion of derivative security	-100%			-50,067,334	0	20 Jun 2025	See Footnote
J. Russel Denton		Common Stock	Purchase	6.46%			7,500	123,591	20 Jun 2025	Direct
David D. Halbert		Common Stock	Conversion of derivative security	644.2%			104,761,535	121,025,002	20 Jun 2025	See Footnotes
David D. Halbert		Series B Preferred Stock	Conversion of derivative security	-100%			-29,629,630	0	20 Jun 2025	See Footnotes
David D. Halbert		Series A Preferred Stock	Conversion of derivative security	-100%			-389,416,484	0	20 Jun 2025	See Footnotes
ADAPT I Ltd.		Common Stock	Conversion of derivative security	26%			3,500,003	16,943,232	20 Jun 2025	See Footnotes
ADAPT I Ltd.		Series A Preferred Stock	Conversion of derivative security	-100%			-14,000,000	0	20 Jun 2025	See Footnotes
Peter M. Castleman		Common Stock	Conversion of derivative security	40983.6%			10,245,906	10,270,906	20 Jun 2025	By CLS-PF-SPE, LLC
Peter M. Castleman		Series A Preferred Stock	Conversion of derivative security	-100%			-40,983,607	0	20 Jun 2025	By CLS-PF-SPE, LLC
Brian J. Brille		Common Stock	Purchase	22.6%			30,000	162,428	20 Jun 2025	Direct
TSSP Sub-Fund HoldCo LLC		Common Stock	Exercise of in-the-money or at-the-money derivative security	20.7%			208,746	1,219,271	20 Jun 2025	Held by Sixth Street Specialty Lending, Inc.

* An asterisk sign (*) next to the price indicates that the price is likely invalid.