Comparable stake leader
RTW INVESTMENTS, LP
SEC ownership of Zai Lab Ltd
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001704292.
Disclosed value leader
Qiming Venture Partners IV, L.P.
Comparable rows
50/50
Latest evidence
02 Jun 2026
- Public ticker
- ZLAB on Nasdaq
- Parsed ownership sources
-
13D/G and 13F
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
- Largest SEC-reported holder
-
RTW INVESTMENTS, LP
Ranking: Comparable ownership first, then disclosed value
- Comparable ownership rows
-
50 of 50
Meaning: Rows with safely comparable ownership %
- Latest 13D/G holder
-
RTW INVESTMENTS, LP
Source: Latest parsed Schedule 13D/G stake
- Latest parsed ownership date
-
02 Jun 2026
Freshness: Most recent filing date in this holder set
- Issuer CIK
- 0001704292
- Issuer location
- Shanghai
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
3 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of Zai Lab Ltd (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
RTW INVESTMENTS, LP
Disclosed value leader
Qiming Venture Partners I...
Comparable rows
50/50
Latest evidence
02 Jun 2026
13D/G
13F
Lead comparable stake: 6.3%
13D/G row: RTW INVESTMENTS, LP
Showing 1-8 of 50 holder rows.
Quick read
RTW INVESTMENTS, LP leads the comparable SEC ownership view at 6.3%.
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens RTW INVESTMENTS, LP's linked filing trail.
Comparable ownership
Top 5
RTW INVESTMENTS, LP
6.3%
Qiming Venture Partners IV, L.P.
6%
TCG Crossover GP II, LLC
5.3%
RA CAPITAL MANAGEMENT, L.P.
5.2%
Qiming Corporate GP IV, Ltd
4.4%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 50 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| RTW INVESTMENTS, LP |
13D/G
13F
Company
|
6.3%
|
$1,258,888,889
69,590,320 shares
|
+$844,379,694 | 31 Dec 2025 |
| Qiming Venture Partners IV, L.P. |
13D/G
Qiming Corporate GP IV, Ltd.
|
6%
|
$2,365,303,551
66,329,320 shares
|
$0 | 30 Jun 2025 |
| TCG Crossover GP II, LLC |
13D/G
Chen Yu
|
5.3%
|
$1,210,406,452
59,130,750 shares
|
$0 | 02 Jun 2026 |
| RA CAPITAL MANAGEMENT, L.P. |
13D/G
13F
Company
|
5.2%
|
$1,083,804,677
57,435,330 shares
|
$0 | 30 Mar 2026 |
| Qiming Corporate GP IV, Ltd |
13D/G
|
4.4%
|
$884,305,102
48,883,643 shares
|
$0 | 31 Dec 2025 |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
|
4.3%
|
—
48,112,590 shares
|
$0 | 31 Dec 2025 |
| FMR LLC |
13F
13D/G
Company
|
3.9%
from 13D/G
|
$23,745,575
1,262,391 shares
|
— | 31 Mar 2026 |
| JANUS HENDERSON GROUP PLC |
13D/G
|
3.6%
|
—
39,501,040 shares
|
$0 | 31 Mar 2025 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$19,361,166.
Buys
$321,833
Insiders: 2
Sells
$19,682,999
Insiders: 6
Net
-$19,361,166
Shares: -779,240
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 11,731
Shares: 790,971
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 248,496 | $0 | $4,978,658 | -$4,978,658 |
| 3-6 | 1,731 | 245,330 | $32,733 | $4,667,847 | -$4,635,114 |
| 6-9 | 0 | 23,675 | $0 | $453,742 | -$453,742 |
| 9-12 | 10,000 | 273,470 | $289,100 | $9,582,752 | -$9,293,652 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-20 of 20 reporting-owner rows connected to Zai Lab Ltd. Open a relationship link for the CIK-to-CIK filing trail.
Rows
20
Largest Forms 3/4/5 holder
Du Ying
Net 12M change
-$19,361,165
Latest report
26 May 2026
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Du Ying | Chairperson & CEO, Director | $21,995,054 | -$16,196,727 | -42% | Mixed | 26 May 2026 |
| Fu Tao | President & COO, Director | $13,303,479 | Mixed | 28 Oct 2021 | ||
| WIRTH PETER | Director | $8,169,424 | Mixed | 18 Jun 2025 | ||
| Joshua L. Smiley | President and Chief Operating Officer | $2,877,838 | -$245,887 | -7.9% | Mixed | 06 Apr 2026 |
| Alan B. Sandler | Head of Global Dev., Oncology | $1,906,906 | Mixed | 25 Jun 2022 | ||
| John D. Diekman | Director | $1,897,457 | Mixed | 18 Jun 2025 | ||
| Harald Reinhart | President and Head of Global Development for Neuroscience, Autoimmune and Infectious Diseases | $1,774,330 | Mixed | 25 Jun 2024 | ||
| William Ki Chul Cho | Chief Financial Officer | $1,603,316 | Mixed | 03 Apr 2023 | ||
| Rafael Amado | President, Head of Global Oncology Research and Development | $1,552,994 | -$779,994 | -33% | Mixed | 06 Apr 2026 |
| Moulder Leon O Jr. | Director | $1,317,860 | Mixed | 18 Jun 2025 | ||
| William Lis | Director | $1,252,231 | -$492,745 | -28% | Filing P/S | 18 Jun 2025 |
| Richard Gaynor | Director | $1,070,873 | +$32,733 | +3.2% | Filing P/S | 17 Mar 2026 |
| Kai-Xian Chen | Director | $1,038,757 | Mixed | 31 Dec 2024 | ||
| Michel Vounatsos | Director | $844,530 | Mixed | 18 Jun 2025 | ||
| Yi Liang | CCO & President, Greater China | $817,619 | Mixed | 25 Jun 2022 | ||
| Yajing Chen | Chief Financial Officer | $813,843 | -$464,119 | -36% | Mixed | 06 Apr 2026 |
| Frazor Titus Edmondson III | Chief Legal Officer | $733,917 | -$1,214,426 | -62% | Mixed | 14 May 2026 |
| Scott W. Morrison | Director | $712,171 | Mixed | 18 Jun 2025 | ||
| Nisa Leung | Director | Mixed | 18 Jun 2025 | |||
| Yizhe Wang | Operating Partner | Mixed | 11 May 2026 |
Recent insider transactions for Zai Lab Ltd
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Du Ying | ZLAB | American Depositary Shares | Gift | -7.05% | -87,843 | 1,158,583 | 27 May 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Gift | -1.57% | -19,857 | 1,246,426 | 26 May 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Tax liability | -8.49% | -117,435 | 1,266,283 | 19 May 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Options Exercise | 23.3% | 261,092 | 1,383,718 | 19 May 2026 | Direct | ||
| Du Ying | ZLAB | Stock Options (Right to Buy) | Options Exercise | -100% | -261,092 | 0 | 19 May 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Sale | -4.26% | $949,765 | $19.00 | -50,000 | 1,122,626 | 18 May 2026 | Direct |
| Du Ying | ZLAB | American Depositary Shares | Options Exercise | 4.45% | 50,000 | 1,172,626 | 18 May 2026 | Direct | ||
| Du Ying | ZLAB | Stock Options (Right to Buy) | Options Exercise | -16.1% | -50,000 | 261,092 | 18 May 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Sale | -4.26% | $1,037,110 | $20.74 | -50,000 | 1,122,626 | 15 May 2026 | Direct |
| Du Ying | ZLAB | American Depositary Shares | Options Exercise | 4.45% | 50,000 | 1,172,626 | 15 May 2026 | Direct | ||
| Du Ying | ZLAB | Stock Options (Right to Buy) | Options Exercise | -13.8% | -50,000 | 311,092 | 15 May 2026 | Direct | ||
| Frazor Titus Edmondson III | ZLAB | American Depositary Shares | Sale | -15% | $71,008 | $20.19 | -3,517 | 19,849 | 14 May 2026 | Direct |
| Du Ying | ZLAB | American Depositary Shares | Sale | -4.26% | $1,004,575 | $20.09 | -50,000 | 1,122,626 | 14 May 2026 | Direct |
| Du Ying | ZLAB | American Depositary Shares | Options Exercise | 4.45% | 50,000 | 1,172,626 | 14 May 2026 | Direct | ||
| Du Ying | ZLAB | Stock Options (Right to Buy) | Options Exercise | -12.2% | -50,000 | 361,092 | 14 May 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Sale | -4.26% | $998,469 | $19.97 | -50,000 | 1,122,626 | 13 May 2026 | Direct |
| Du Ying | ZLAB | American Depositary Shares | Options Exercise | 4.45% | 50,000 | 1,172,626 | 13 May 2026 | Direct | ||
| Du Ying | ZLAB | Stock Options (Right to Buy) | Options Exercise | -10.8% | -50,000 | 411,092 | 13 May 2026 | Direct | ||
| Yizhe Wang | ZLAB | Restricted Share Units | Award | 59,288 | 59,288 | 11 May 2026 | Direct | |||
| Yizhe Wang | ZLAB | Stock Option (Right to Buy) | Award | 136,819 | 136,819 | 11 May 2026 | Direct | |||
| Joshua L. Smiley | ZLAB | American Depositary Shares | Sale | -2.5% | $61,692 | $20.45 | -3,017 | 117,602 | 06 Apr 2026 | Direct |
| Frazor Titus Edmondson III | ZLAB | American Depositary Shares | Sale | -4.98% | $25,028 | $20.45 | -1,224 | 23,366 | 06 Apr 2026 | Direct |
| Du Ying | ZLAB | American Depositary Shares | Sale | -0.24% | $54,249 | $20.45 | -2,653 | 1,122,626 | 06 Apr 2026 | Direct |
| Yajing Chen | ZLAB | American Depositary Shares | Sale | -2.62% | $17,442 | $20.45 | -853 | 31,705 | 06 Apr 2026 | Direct |
| Rafael Amado | ZLAB | American Depositary Shares | Sale | -4.58% | $56,007 | $20.45 | -2,739 | 57,022 | 06 Apr 2026 | Direct |
| Joshua L. Smiley | ZLAB | American Depositary Shares | Sale | -7.38% | $196,029 | $20.39 | -9,614 | 120,619 | 02 Apr 2026 | Direct |
| Joshua L. Smiley | ZLAB | American Depositary Shares | Options Exercise | 5.8% | 7,145 | 130,233 | 02 Apr 2026 | Direct | ||
| Joshua L. Smiley | ZLAB | Restricted Share Units | Options Exercise | -50% | -7,145 | 7,145 | 02 Apr 2026 | Direct | ||
| Frazor Titus Edmondson III | ZLAB | American Depositary Shares | Sale | -14.6% | $85,516 | $20.39 | -4,194 | 24,590 | 02 Apr 2026 | Direct |
| Frazor Titus Edmondson III | ZLAB | American Depositary Shares | Options Exercise | 21.2% | 5,031 | 28,784 | 02 Apr 2026 | Direct | ||
| Frazor Titus Edmondson III | ZLAB | Restricted Share Units | Options Exercise | -50% | -5,031 | 5,032 | 02 Apr 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Sale | -0.49% | $113,695 | $20.39 | -5,576 | 1,125,279 | 02 Apr 2026 | Direct |
| Du Ying | ZLAB | American Depositary Shares | Options Exercise | 0.6% | 6,750 | 1,130,855 | 02 Apr 2026 | Direct | ||
| Du Ying | ZLAB | Restricted Share Units | Options Exercise | -33.3% | -6,750 | 13,500 | 02 Apr 2026 | Direct | ||
| Yajing Chen | ZLAB | American Depositary Shares | Sale | -13.8% | $106,008 | $20.39 | -5,199 | 32,558 | 02 Apr 2026 | Direct |
| Yajing Chen | ZLAB | American Depositary Shares | Options Exercise | 7.09% | 2,500 | 37,757 | 02 Apr 2026 | Direct | ||
| Yajing Chen | ZLAB | Restricted Share Units | Options Exercise | -50% | -2,500 | 2,500 | 02 Apr 2026 | Direct | ||
| Rafael Amado | ZLAB | American Depositary Shares | Sale | -14.2% | $202,065 | $20.39 | -9,910 | 59,761 | 02 Apr 2026 | Direct |
| Rafael Amado | ZLAB | American Depositary Shares | Options Exercise | 8.39% | 5,391 | 69,671 | 02 Apr 2026 | Direct | ||
| Rafael Amado | ZLAB | Restricted Share Units | Options Exercise | -50% | -5,391 | 5,391 | 02 Apr 2026 | Direct | ||
| Joshua L. Smiley | ZLAB | American Depositary Shares | Options Exercise | 35.2% | 32,062 | 123,088 | 01 Apr 2026 | Direct | ||
| Joshua L. Smiley | ZLAB | Restricted Share Units | Options Exercise | -33.3% | -32,062 | 64,125 | 01 Apr 2026 | Direct | ||
| Frazor Titus Edmondson III | ZLAB | American Depositary Shares | Options Exercise | 265.8% | 17,259 | 23,753 | 01 Apr 2026 | Direct | ||
| Frazor Titus Edmondson III | ZLAB | Restricted Share Units | Options Exercise | -100% | -17,259 | 0 | 01 Apr 2026 | Direct | ||
| Du Ying | ZLAB | American Depositary Shares | Options Exercise | 1.28% | 14,200 | 1,124,105 | 01 Apr 2026 | Direct | ||
| Du Ying | ZLAB | Restricted Share Units | Options Exercise | -100% | -14,200 | 0 | 01 Apr 2026 | Direct | ||
| Yajing Chen | ZLAB | American Depositary Shares | Options Exercise | 76.3% | 15,258 | 35,257 | 01 Apr 2026 | Direct | ||
| Yajing Chen | ZLAB | Restricted Share Units | Options Exercise | -91% | -15,258 | 1,500 | 01 Apr 2026 | Direct | ||
| Rafael Amado | ZLAB | American Depositary Shares | Options Exercise | 43.6% | 19,523 | 64,280 | 01 Apr 2026 | Direct | ||
| Rafael Amado | ZLAB | Restricted Share Units | Options Exercise | -33.3% | -19,523 | 39,046 | 01 Apr 2026 | Direct |
* marks a reported price that did not pass the local price check.