SEC ownership of Silence Therapeutics plc

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001479615.

Comparable stake leader

Richard Ian Griffiths

Disclosed value leader

Invus Global Management, LLC

Comparable rows

50/50

Latest evidence

12 Aug 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
Richard Ian Griffiths
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
12 Aug 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001479615
Issuer location
London

Ownership snapshot

Top shareholders of Silence Therapeutics plc (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Richard Ian Griffiths
Disclosed value leader
Invus Global Management, LLC
Comparable rows
50/50
Latest evidence
12 Aug 2026
13D/G 3/4/5 13F Lead comparable stake: 8% 13D/G row: Richard Ian Griffiths Showing 1-8 of 50 holder rows.

Quick read

Richard Ian Griffiths leads the comparable SEC ownership view at 8%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Richard Ian Griffiths's linked filing trail.
Comparable ownership Top 5
Richard Ian Griffiths 8%
Invus Global Management, LLC 7%
Redmile Group, LLC 4.7%
Lombard Odier Asset Management (U... 4.2%
Siren, L.L.C. 2.3%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Richard Ian Griffiths
13D/G 3/4/5
Richard Griffiths · 10%+ Owner
8%
14,391,498 shares
$0 12 Aug 2026
Invus Global Management, LLC
13D/G
Raymond Debbane
7%
$90,302,914
9,934,314 shares
$0 30 Jun 2026
Redmile Group, LLC
13F 13D/G
Company
4.7%
from 13D/G
$23,769,251
2,164,777 shares
30 Jun 2026
Lombard Odier Asset Management (USA) Corp
13D/G
4.2%
5,935,955 shares
$0 31 Dec 2025
Siren, L.L.C.
13F
Individual
13F
2.3%
$36,359,589
3,311,438 shares
30 Jun 2026
TCG Crossover Management, LLC
13F
Company
13F
2.1%
$33,308,489
3,033,560 shares
30 Jun 2026
Nantahala Capital Management, LLC
13F
Company
13F
0.95%
$14,787,106
1,346,731 shares
30 Jun 2026
CITADEL ADVISORS LLC
13F
Company
13F
0.94%
$14,599,282
1,329,625 shares
30 Jun 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Insider buy and sell flow is broadly balanced over the last 12 months. No Buy or Sell transactions have been reported since 28 Aug 2025.

Buys
$0
Insiders: 0
Sells
$0
Insiders: 0
Net
$0
Shares: 0
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 0
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 0 0 $0 $0 $0
9-12 0 0 $0 $0 $0

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-9 of 9 reporting-owner rows connected to Silence Therapeutics plc. Open a relationship link for the CIK-to-CIK filing trail.

Rows
9
Largest Forms 3/4/5 holder
Steven J. Romano
Net 12M change
$0
Latest report
10 Aug 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Steven J. Romano EVP and Chief R&D Officer Mixed 02 Jan 2026
David Lemus Director Mixed 02 Jan 2026
Rhonda Lynette Hellums Chief Financial Officer, Director Mixed 02 Jan 2026
Michael H. Davidson Director Mixed 02 Jan 2025
James Ede-Golightly Director Mixed 02 Jan 2026
Iain Ross Interim PEO, Director Mixed 18 Dec 2025
Craig A. Tooman President and CEO, Director Mixed 02 Jan 2025
Timothy Mcinerney Director Mixed 02 Jan 2026
Richard Ian Griffiths 10%+ Owner Mixed 10 Aug 2026

Recent insider transactions for Silence Therapeutics plc

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Richard Ian Griffiths SLN American Depositary Shares Sale 273.6% 5,484,320 7,488,660 10 Aug 2026 See footnote
Richard Ian Griffiths SLN American Depositary Shares Sale 9.19% 865,112 10,281,486 06 Jul 2026 See footnote
Richard Ian Griffiths SLN American Depositary Shares Sale 0.45% 50,082 11,146,598 02 Jul 2026 See footnote
Richard Ian Griffiths SLN American Depositary Shares Sale 1.16% 129,180 11,246,680 01 Jul 2026 See footnote
Richard Ian Griffiths SLN American Depositary Shares Sale 1.52% 169,928 11,325,860 30 Jun 2026 See footnote
Richard Ian Griffiths SLN American Depositary Shares Sale 2.96% 330,072 11,495,788 29 Jun 2026 See footnote
James Ede-Golightly SLN Share Option (Right to Buy) Award 90,000 90,000 02 Jan 2026 Direct
Timothy Mcinerney SLN Share Option (Right to Buy) Award 90,000 90,000 02 Jan 2026 Direct
Steven J. Romano SLN Employee Share Option (Right to Buy) Award 300,000 300,000 02 Jan 2026 Direct
Rhonda Lynette Hellums SLN Employee Share Option (Right to Buy) Award 375,000 375,000 02 Jan 2026 Direct
David Lemus SLN Share Option (Right to Buy) Award 90,000 90,000 02 Jan 2026 Direct
James Ede-Golightly SLN Share Option (Right to Buy) Award 90,000 90,000 22 Dec 2025 Direct
Iain Ross SLN Employee Share Option (Right to Buy) Award 900,000 900,000 18 Dec 2025 Direct
Richard Ian Griffiths SLN American Depositary Shares Purchase 0.02% 2,000 11,825,861 27 Oct 2025 See footnote
Richard Ian Griffiths SLN American Depositary Shares Sale 0.02% 2,000 11,819,861 27 Oct 2025 See footnote
* marks a reported price that did not pass the local price check.
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