Comparable stake leader
Richard Ian Griffiths
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001479615.
Comparable stake leader
Richard Ian Griffiths
Disclosed value leader
Invus Global Management, LLC
Comparable rows
50/50
Latest evidence
12 Aug 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Richard Ian Griffiths |
13D/G
3/4/5
Richard Griffiths · 10%+ Owner
|
8%
|
—
14,391,498 shares
|
$0 | 12 Aug 2026 |
| Invus Global Management, LLC |
13D/G
Raymond Debbane
|
7%
|
$90,302,914
9,934,314 shares
|
$0 | 30 Jun 2026 |
| Redmile Group, LLC |
13F
13D/G
Company
|
4.7%
from 13D/G
|
$23,769,251
2,164,777 shares
|
— | 30 Jun 2026 |
| Lombard Odier Asset Management (USA) Corp |
13D/G
|
4.2%
|
—
5,935,955 shares
|
$0 | 31 Dec 2025 |
| Siren, L.L.C. |
13F
Individual
|
2.3%
|
$36,359,589
3,311,438 shares
|
— | 30 Jun 2026 |
| TCG Crossover Management, LLC |
13F
Company
|
2.1%
|
$33,308,489
3,033,560 shares
|
— | 30 Jun 2026 |
| Nantahala Capital Management, LLC |
13F
Company
|
0.95%
|
$14,787,106
1,346,731 shares
|
— | 30 Jun 2026 |
| CITADEL ADVISORS LLC |
13F
Company
|
0.94%
|
$14,599,282
1,329,625 shares
|
— | 30 Jun 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider buy and sell flow is broadly balanced over the last 12 months. No Buy or Sell transactions have been reported since 28 Aug 2025.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 0 | $0 | $0 | $0 |
| 3-6 | 0 | 0 | $0 | $0 | $0 |
| 6-9 | 0 | 0 | $0 | $0 | $0 |
| 9-12 | 0 | 0 | $0 | $0 | $0 |
Reporting owners
Showing 1-9 of 9 reporting-owner rows connected to Silence Therapeutics plc. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Steven J. Romano | EVP and Chief R&D Officer | Mixed | 02 Jan 2026 | |||
| David Lemus | Director | Mixed | 02 Jan 2026 | |||
| Rhonda Lynette Hellums | Chief Financial Officer, Director | Mixed | 02 Jan 2026 | |||
| Michael H. Davidson | Director | Mixed | 02 Jan 2025 | |||
| James Ede-Golightly | Director | Mixed | 02 Jan 2026 | |||
| Iain Ross | Interim PEO, Director | Mixed | 18 Dec 2025 | |||
| Craig A. Tooman | President and CEO, Director | Mixed | 02 Jan 2025 | |||
| Timothy Mcinerney | Director | Mixed | 02 Jan 2026 | |||
| Richard Ian Griffiths | 10%+ Owner | Mixed | 10 Aug 2026 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Richard Ian Griffiths | SLN | American Depositary Shares | Sale | 273.6% | 5,484,320 | 7,488,660 | 10 Aug 2026 | See footnote | ||
| Richard Ian Griffiths | SLN | American Depositary Shares | Sale | 9.19% | 865,112 | 10,281,486 | 06 Jul 2026 | See footnote | ||
| Richard Ian Griffiths | SLN | American Depositary Shares | Sale | 0.45% | 50,082 | 11,146,598 | 02 Jul 2026 | See footnote | ||
| Richard Ian Griffiths | SLN | American Depositary Shares | Sale | 1.16% | 129,180 | 11,246,680 | 01 Jul 2026 | See footnote | ||
| Richard Ian Griffiths | SLN | American Depositary Shares | Sale | 1.52% | 169,928 | 11,325,860 | 30 Jun 2026 | See footnote | ||
| Richard Ian Griffiths | SLN | American Depositary Shares | Sale | 2.96% | 330,072 | 11,495,788 | 29 Jun 2026 | See footnote | ||
| James Ede-Golightly | SLN | Share Option (Right to Buy) | Award | 90,000 | 90,000 | 02 Jan 2026 | Direct | |||
| Timothy Mcinerney | SLN | Share Option (Right to Buy) | Award | 90,000 | 90,000 | 02 Jan 2026 | Direct | |||
| Steven J. Romano | SLN | Employee Share Option (Right to Buy) | Award | 300,000 | 300,000 | 02 Jan 2026 | Direct | |||
| Rhonda Lynette Hellums | SLN | Employee Share Option (Right to Buy) | Award | 375,000 | 375,000 | 02 Jan 2026 | Direct | |||
| David Lemus | SLN | Share Option (Right to Buy) | Award | 90,000 | 90,000 | 02 Jan 2026 | Direct | |||
| James Ede-Golightly | SLN | Share Option (Right to Buy) | Award | 90,000 | 90,000 | 22 Dec 2025 | Direct | |||
| Iain Ross | SLN | Employee Share Option (Right to Buy) | Award | 900,000 | 900,000 | 18 Dec 2025 | Direct | |||
| Richard Ian Griffiths | SLN | American Depositary Shares | Purchase | 0.02% | 2,000 | 11,825,861 | 27 Oct 2025 | See footnote | ||
| Richard Ian Griffiths | SLN | American Depositary Shares | Sale | 0.02% | 2,000 | 11,819,861 | 27 Oct 2025 | See footnote |