Lombard Odier Asset Management (USA) Corp - 31 Dec 2025 SCHEDULE 13G/A Report for Silence Therapeutics plc Ordinary Shares, par value GBP 0.05 per share (the "Shares")

Filing Manager: Lombard Odier Asset Management (USA) Corp
Reporting Manager: Lombard Odier Asset Management (USA) Corp
Security: Silence Therapeutics plc Ordinary Shares, par value GBP 0.05 per share (the "Shares")
Shares outstanding: 141,332,262 shares
Disclosed Ownership: 5,935,955 shares
Ownership: 4.2%
Form type: SCHEDULE 13G/A
Filing time: 09 Feb 2026, 13:16:36 UTC
Date of event: 31 Dec 2025
Previous filing: 11 Feb 2025
SEC: View on sec.gov

Reporting Managers (1)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
Lombard Odier Asset Management (USA) Corp	4.2%	5,935,955	0	5,935,955	/s/ Elyse Strauss	Authorized Signatory