Comparable stake leader
Opaleye Management Inc.
SEC ownership of CODEXIS, INC.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001200375.
Disclosed value leader
Opaleye Management Inc.
Comparable rows
50/50
Latest evidence
30 Jun 2026
- Public ticker
- CDXS on Nasdaq
- Parsed ownership sources
-
3/4/5, 13D/G, and 13F
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
- Largest SEC-reported holder
-
Opaleye Management Inc.
Ranking: Comparable ownership first, then disclosed value
- Comparable ownership rows
-
50 of 50
Meaning: Rows with safely comparable ownership %
- Latest 13D/G holder
-
Opaleye Management Inc.
Source: Latest parsed Schedule 13D/G stake
- Latest parsed ownership date
-
30 Jun 2026
Freshness: Most recent filing date in this holder set
- Issuer CIK
- 0001200375
- Issuer location
- Redwood City, CA
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
3 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of CODEXIS, INC. (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
Opaleye Management Inc.
Disclosed value leader
Opaleye Management Inc.
Comparable rows
50/50
Latest evidence
30 Jun 2026
3/4/5
13D/G
13F
Lead comparable stake: 7.5%
13D/G row: Opaleye Management Inc.
Showing 1-8 of 50 holder rows.
Quick read
Opaleye Management Inc. leads the comparable SEC ownership view at 7.5%.
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens Opaleye Management Inc.'s linked filing trail.
Comparable ownership
Top 5
Opaleye Management Inc.
7.5%
Aberdeen Group plc
7.4%
BlackRock, Inc.
7.2%
INTEGRATED CORE STRATEGIES (US) LLC
5.2%
Laurence W. Lytton
5%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 50 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Opaleye Management Inc. |
3/4/5
13D/G
13F
10%+ Owner · Company
|
7.5%
from 13D/G
|
$16,900,093
10,134,989 shares
|
-$1,142,779 | 26 Nov 2025 |
| Aberdeen Group plc |
13D/G
13F
Company
|
7.4%
|
$15,300,096
6,769,954 shares
|
-$2,704,189 | 30 Jun 2026 |
| BlackRock, Inc. |
13D/G
13F
Company
|
7.2%
|
$13,752,804
5,979,480 shares
|
$0 | 31 Mar 2025 |
| INTEGRATED CORE STRATEGIES (US) LLC |
13D/G
|
5.2%
|
$7,812,135
4,734,627 shares
|
$0 | 09 Apr 2026 |
| Laurence W. Lytton |
13D/G
LYTTON LAURENCE W
|
5%
|
$5,347,841
4,532,069 shares
|
$0 | 06 Mar 2026 |
| Nantahala Capital Management, LLC |
13D/G
13F
Company
|
4.3%
|
$6,825,958
2,967,808 shares
|
$0 | 30 Sep 2024 |
| FMR LLC |
13D/G
13F
Company
|
0.6%
|
$1,425,855
584,367 shares
|
$0 | 30 Sep 2025 |
| Dennis P. Wolf |
3/4/5
Director
|
0.15%
|
$217,124
138,951 shares
|
-$13,988 | 21 Nov 2025 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$1,224,507.
Buys
$1,980,189
Insiders: 1
Sells
$3,204,697
Insiders: 6
Net
-$1,224,507
Shares: -831,150
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 985,000
Shares: 1,816,150
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 2,605 | $0 | $6,174 | -$6,174 |
| 3-6 | 0 | 16,006 | $0 | $19,900 | -$19,900 |
| 6-9 | 890,000 | 1,785,061 | $1,724,108 | $3,147,365 | -$1,423,257 |
| 9-12 | 95,000 | 12,478 | $256,081 | $31,258 | +$224,823 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 21-22 of 22 reporting-owner rows connected to CODEXIS, INC.. Open a relationship link for the CIK-to-CIK filing trail.
Rows
22
Largest Forms 3/4/5 holder
Opaleye Management Inc.
Net 12M change
-$1,224,507
Latest report
17 Jun 2026
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Georgia Erbez | Chief Financial Officer and Chief Business Officer | $87,327 | -$20,630 | -19% | Filing P/S | 23 Feb 2026 |
| Dean Ross Taylor Jr. | Advisor | $81,287 | Mixed | 07 Feb 2023 |
Recent insider transactions for CODEXIS, INC.
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Parker H Stewart | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| Cynthia Collins | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| Christos Richards | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| David V Smith | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| Rahul Singhvi | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| Esther Martinborough | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| Stephen G. Dilly | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| Raymond de Vre | CDXS | Stock Option (Right to Buy) | Award | 66,350 | 66,350 | 17 Jun 2026 | Direct | |||
| Raymond de Vre | CDXS | Common Stock | Sale | -2.98% | $6,174 | $2.37 | -2,605 | 84,811 | 11 Jun 2026 | Direct |
| Stefan Lutz | CDXS | Common Stock | Sale | -4.3% | $6,641 | $1.13 | -5,862 | 130,421 | 24 Feb 2026 | Direct |
| Stefan Lutz | CDXS | Stock Option (Right to Buy) | Award | 316,100 | 316,100 | 23 Feb 2026 | Direct | |||
| Alison Moore | CDXS | Stock Option (Right to Buy) | Award | 993,000 | 993,000 | 23 Feb 2026 | Direct | |||
| Georgia Erbez | CDXS | Stock Option (Right to Buy) | Award | 316,100 | 316,100 | 23 Feb 2026 | Direct | |||
| Stefan Lutz | CDXS | Common Stock | Sale | -1.8% | $3,257 | $1.31 | -2,492 | 136,283 | 06 Feb 2026 | Direct |
| Georgia Erbez | CDXS | Common Stock | Sale | -5.42% | $5,001 | $1.31 | -3,826 | 66,810 | 06 Feb 2026 | Direct |
| Alison Moore | CDXS | Common Stock | Sale | -1.5% | $5,001 | $1.31 | -3,826 | 250,506 | 06 Feb 2026 | Direct |
| Stefan Lutz | CDXS | Common Stock | Sale | -3.27% | $7,950 | $1.70 | -4,685 | 138,775 | 07 Jan 2026 | Direct |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -4.53% | $14,229 | $1.67 | -8,533 | 179,989 | 01 Dec 2025 | By Managed Account |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -2.4% | $408,538 | $1.67 | -245,000 | 9,955,000 | 01 Dec 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -1.3% | $4,358 | $1.75 | -2,490 | 188,522 | 28 Nov 2025 | By Managed Account |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -1.02% | $183,750 | $1.75 | -105,000 | 10,200,000 | 28 Nov 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -2.55% | $8,706 | $1.74 | -5,000 | 191,012 | 26 Nov 2025 | By Managed Account |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -1.42% | $258,266 | $1.74 | -148,318 | 10,305,000 | 26 Nov 2025 | By Opaleye, L.P. |
| Dennis P. Wolf | CDXS | Common Stock | Sale | -6.05% | $13,988 | $1.56 | -8,952 | 138,951 | 21 Nov 2025 | Direct |
| Alison Moore | CDXS | Common Stock | Award | 50.2% | 85,000 | 254,332 | 13 Nov 2025 | Direct | ||
| Alison Moore | CDXS | Stock Option (Right to Buy) | Award | 500,000 | 500,000 | 13 Nov 2025 | Direct | |||
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -1.55% | $323,730 | $1.96 | -165,000 | 10,453,318 | 12 Nov 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -12.3% | $53,194 | $1.94 | -27,459 | 196,012 | 12 Nov 2025 | By Managed Account |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | 9.15% | $1,724,108 | $1.94 | 890,000 | 10,618,318 | 12 Nov 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -5.58% | $23,772 | $1.80 | -13,211 | 223,461 | 11 Nov 2025 | By Managed Account |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -4.44% | $962,679 | $1.80 | -535,000 | 11,508,318 | 11 Nov 2025 | By Opaleye, L.P. |
| Raymond de Vre | CDXS | Common Stock | Sale | -1.59% | $2,459 | $1.74 | -1,413 | 87,416 | 11 Nov 2025 | Direct |
| Stephen G. Dilly | CDXS | Common Stock | Award | 7.38% | 50,000 | 727,053 | 11 Nov 2025 | Direct | ||
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -1.38% | $5,756 | $1.73 | -3,318 | 236,682 | 10 Nov 2025 | By Managed Account |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -1.67% | $355,614 | $1.73 | -205,000 | 12,043,318 | 10 Nov 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -4% | $16,968 | $1.70 | -10,000 | 240,000 | 07 Nov 2025 | By Managed Account |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Sale | -2.36% | $503,410 | $1.70 | -296,682 | 12,248,318 | 07 Nov 2025 | By Opaleye, L.P. |
| Alison Moore | CDXS | Common Stock | Sale | -3.55% | $15,629 | $2.51 | -6,239 | 169,332 | 13 Oct 2025 | Direct |
| Georgia Erbez | CDXS | Common Stock | Sale | -8.12% | $15,629 | $2.50 | -6,239 | 70,636 | 13 Oct 2025 | Direct |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Purchase | 0.01% | $2,211 | $2.84 | 780 | 12,545,000 | 04 Aug 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Purchase | 0.68% | $225,710 | $2.68 | 84,220 | 12,544,220 | 31 Jul 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Purchase | 0.01% | $4,411 | $2.80 | 1,578 | 12,460,000 | 30 Jul 2025 | By Opaleye, L.P. |
| Opaleye Management Inc. | CDXS | Common Stock, par value $0.001 per share | Purchase | 0.07% | $23,750 | $2.82 | 8,422 | 12,458,422 | 29 Jul 2025 | By Opaleye, L.P. |
* marks a reported price that did not pass the local price check.